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Vol 10, No 3 (2013)

Articles
Peanut allergy: update concepts
Ogorodova L.M., Fedorova O.S., Fedotova M.M., Evdokimova T.A.
Abstract
Allergy to peanuts is an actual problem of practical health care associated with a significant prevalence and severity of peanut-allergic reactions, which can include anaphylaxis. The characteristic of peanut allergen components is presented in the review. Modern approaches to the diagnosis of allergy to peanuts reflected in the article. The article presents research findings on development and natural history of allergy to peanuts, clinical mmanifestations, also considered the priority therapeutic approaches.
Russian Journal of Allergy. 2013;10(3):3-10
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Current understanding of drug`s hypersensitivity reactions classification and pathogenesis
Zhukova D.G., Fedenko E.S., Yudin A.A., Tsyvkina E.A., Goncharov N.G.
Abstract
Drug’s side effects are considered to be a difficult area of medicine. This review covers adverse drugs reactions classification, current understanding of pathogenesis and pharmacovigilance.
Russian Journal of Allergy. 2013;10(3):11-16
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Food anaphylaxis in children: diagnosis and treatment
Esakova N.V., Pampura A.N.
Abstract
The proper diagnose of anaphylaxis is based on the early recognition of symptoms, term definitions and the reasons of anaphylaxis reaction development. Modern data on the diagnostics of food anaphylaxis and a number of symptoms’ features are given in the article. The basic principles of treatment and anaphylaxis prevention are considered.
Russian Journal of Allergy. 2013;10(3):17-24
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Moscow newborns: a demand of primary dietary prophylaxis of allergy
Geneva M.S., Pampura A.N.
Abstract
Background. Primary prevention of allergic diseases in children is specified by the increase of allergic diseases prevalence in a population and may be mediated through the special milk formulas. The study aimed to evaluate the prevalence of allergic symptoms in families of Moscow newborns and to evaluate the hypothetic demand in a special milk formula dietary supplement. Methods. 18 visits to the Postnatal Department of Moscow No.1 Maternity Hospital were carried out. All women delivered in the preceding 48 hours were questioned on each visit. Information on relatives of a newborns family and on allergic manifestations in them has been obtained from the mothers. Information on 3534 relatives of 393 newborns was collected. Results. Moscow newborns-2011 cohort have allergy manifestations in one close relative within 41,7% families, in two or more relatives within 14,5% families. In case of all relatives studied the respective prevalence is 59% and 25,1%. Conclusion. Moscow newborns-2011 primary prevention of allergy (including special formula supplement) is probable in 14,5 % families in case of two or more close relatives with allergies and in 25% families in case two or more relatives with allergy within the wide range of them.
Russian Journal of Allergy. 2013;10(3):24-29
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Influence of the Рriorix vaccination on cytokine profile and IgE level in healthy children and patients with atopic dermatitis
Toptygina A.P., Alioshkin V.A.
Abstract
Background. The aim of the study was to investigate peculiarities of immune responses on the vaccination with Priorix in healthy children and patients with atopic dermatitis. Methods. Thirty five healthy children aged 1-2 years old (Group 1) and 15 children the same age with atopic dermatitis (Group 2) were vaccinated with Priorix. Serum level of IgE was measured by ELISA, and serum concentrations of 7 cytokines: IL-4, IL-5, IL-6, IL-8, IL-10, IFN-γ, and TNF-α were measured by BioPlex technology before vaccination, 7 days, and 30 days after. Serum level of IgE was measured by ELISA. Results. The level of serum IgE relatively decreased or increased on seventh day after vaccination. In a month IgE level returned back. It was found that in group1 51,4% children demonstrated Th1 type response and 48,6% children showed Th2 type response on the vaccination. Similar distribution was obtained in group 2 (53,3% children showed Th1 type response and 46,7% children demonstrated Th2 type). A significant positive correlation was observed between IgE level increasing and Th2 type of immune response. It was shown that 68,6% of children of group 1 and 66,7% of children of group 2 demonstrated after vaccination the superiority of anti-inflammatory IL-10 over pro-inflammatory TNF-α. We suppose that children with atopic dermatitis can be vaccinated with Priorix.
Russian Journal of Allergy. 2013;10(3):30-34
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Features of delayed hypersensitivity reactions to iodinated contrast media diagnosis. Clinical cases
Lebedeva N.V., Myasnikova T.N., Latysheva T.V.
Abstract
The article presents the proprietary data of the survey of patients who had undergone a history of hypersensitivity reactions after administration of iodinated contrast media (RCM), the estimation of skin tests with RCM in these patients and two clinical cases of patients who had a history of delayed-type hypersensitivity.
Russian Journal of Allergy. 2013;10(3):35-40
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Skin care products for sensitive skin
Filimonova T.M., Shtyrbul O.V., Fedenko E.S.
Abstract
This article deals with skin care of sensitive, irritated skin. Application of the daily basic skin care products improves the effectiveness of treatment and quality of life of patients with sensitive skin.
Russian Journal of Allergy. 2013;10(3):41-44
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Safety and physiological action of probiotics as remedies for immune correction
Kalyuzhin O.V.
Abstract
Disclosure of mechanisms that are used by the intestinal microbiota to maintain host immune homeostasis has established a scientific basis for the use of probiotics as immunomodulators. From the standpoint of physiological action, probiotics seem to be attractive targets for the search of effective remedies to strengthen antiinfectious immune response. The potential to cause intestinal and extraintestinal infections and to disseminate genes of antimicrobial resistance necessitates careful monitoring of probiotic strains safety. WHO, FAO, EFSA and some other international organizations have formulated the principles for assessment of probiotic safety and efficacy, which contribute to the appearance on the market of reliable remedies for the correction of immune disorders.
Russian Journal of Allergy. 2013;10(3):45-56
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Epidermal barrier disfunction correction in atopic dermatitis patients
Shvets S.M., Elisyutina O.G.
Abstract
In the article data about epidermal barrier disfunction in atopic dermatitis patients and modern approaches to their correction with use of modern skin-care products are submitted.
Russian Journal of Allergy. 2013;10(3):57-60
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XII International Congress «Modern problems of Immunology, Allergology and Immunophar-macology»
Ilina N.I., Goudima G.O.
Russian Journal of Allergy. 2013;10(3):61-65
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Congresses, Conferences
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Russian Journal of Allergy. 2013;10(3):66-66
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To the memory of Kovalchuk Leonid Vasilievich
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Russian Journal of Allergy. 2013;10(3):67-71
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Instructions for Authors
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Russian Journal of Allergy. 2013;10(3):72-75
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