Email this article 
THE IMPACT OF SUBLINGUAL ALLERGEN IMMUNOTHERAPY ON ASTHMA CONTROL AND THE QUALITY OF LIFE LEVEL IN PATIENTS WITH ALLERGIC ASTHMA AND SENSITIZATION TO TREES POLLEN
- Authors: NAGATKIN DA1, ZHESTKOV AV1
-
Affiliations:
- Samara state medical university
- Issue: Vol 11, No 4 (2014)
- Pages: 50-54
- Section: Articles
- URL: https://rusalljournal.ru/raj/article/view/616
- DOI: https://doi.org/10.36691/RJA616
- ID: 616
Cite item
Open Access
Access granted
Abstract
Background. To Evaluate the effects of trees pollen sublingual products on the control and quality of life in patients with allergic asthma and proven sensitization to pollens of trees. Methods. We enrolled 56 patients in open prospective study and divided into 2 groups to assess the effectiveness of therapy with sublingual allergen. Groups were matched on estimated parameters of quality of life, level of control and forced expiratory volume in the first second. Results. Statistically significant improvement of quality of life parameters and the level of control within the group receiving sublingual immunotherapy was obtained. Significant difference in the average dose of received inhaled corticosteroids was established in the treatment group comparing to control. Conclusion. Sublingual allergen specific immunotherapy has a positive impact on quality of life and level of control in patients with allergic asthma and proven sensitization to pollens of trees, and decreasing the dose of inhaled corticosteroids.
Full Text
About the authors
D A NAGATKIN
Samara state medical university
Email: dmitrynagatkin@gmail.com
A V ZHESTKOV
Samara state medical university
References
- Pajno G.B., Caminiti L., Passalacqua G. Changing the route of immunotherapy administration: An 18-year survey in pediatric patients with allergic rhinitis and asthma. Allergy Asthma Proc. 2013, v. 34, p. 523-526.
- Calderon M.A., Casale T.B., Nelson H.S., Demoly P. An evidence based analysis of house dust mite allergen immunotherapy: A call for more rigorous clinical studies. J. Allergy Clin. Immunol. 2013, v. 132, p. 1322-1336.
- Wood R.A., Togias A., Wildfire J. et al. Development of cock- roach immunotherapy by the InnerCity Asthma Consortium. J. Allergy Clin. Immunol. 2014, v. 133, p. 846-852.
- Yukselen A., Kendirli S.G., Yilmaz M. et al. Two year fol- low-up of clinical and inflammation parameters in children monosensitized to mites undergoing subcutaneous and sub- lingual immunotherapy. Asian Pac. J. Allergy Immunol.2013, v. 31, p. 233-241.
Supplementary files
