The role of atopy patch test with aeroallergens in allergic diseases diagnostics

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Allergic diseases are increasingly becoming a global epidemic and pose a considerable and growing public health burden. Allergy is a systemic T2-dependent inflammatory reaction to an allergen that results from a complex interaction between genetic and environmental factors. Allergic diseases occur through a T2-dependent type of allergic reaction, some of them, in particular atopic dermatitis (AD) and asthma, develop involving different types of hypersensitivity or their combination and require revision of allergy diagnostics. Atopy patch test (APT) can be informative in establishing a role of cell-mediated hypersensitivity in pathogenesis of allergic diseases.

The review presents the recent data on the significance of APT in the diagnostics of skin and respiratory allergies.

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About the authors

Eugeniy V. Smolnikov

NRCI Institute of Immunology FMBA of Russia

Author for correspondence.
ORCID iD: 0000-0003-1302-4178

Graduate student in the Department of Skin Allergy and Immunopathology

Russian Federation, Moscow

Alla O. Litovkina

NRCI Institute of Immunology FMBA of Russia

ORCID iD: 0000-0002-5021-9276

Graduate student in the Department of Skin Allergy and Immunopathology

Russian Federation, Moscow

Ksenia I. Kolykhalova

I.M. Sechenov First Moscow State Medical University (Sechenov University)

ORCID iD: 0000-0002-1389-5566


Russian Federation, Moscow

Olga G. Elisyutina

NRCI Institute of Immunology FMBA of Russia

ORCID iD: 0000-0002-4609-2591

Leading researcher of the Department of Skin Allergy and Immunopathology

Russian Federation, Moscow

Elena S. Fedenko

NRCI Institute of Immunology FMBA of Russia

ORCID iD: 0000-0003-3358-5087
SPIN-code: 5012-7242
Scopus Author ID: 6603386923
ResearcherId: P-6912-2015

Head of the Department of Skin Allergy and Immunopathology

Russian Federation, Moscow


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