Russian Journal of AllergyRussian Journal of AllergyРоссийский Аллергологический Журнал1810-88302686-682XPublishing House ABV Press135510.36691/RJA1355ReviewsНаучные обзорыResearch ArticleThe role of atopy patch test with aeroallergens in allergic diseases diagnosticsДиагностическая значимость аппликационного теста с ингаляционными аллергенами у больных аллергическими заболеваниямиhttps://orcid.org/0000-0003-1302-4178SmolnikovEugeniy V.СмольниковЕвгений Валентинович
Russian Federation

Graduate student in the Department of Skin Allergy and Immunopathology

аспирант отделения аллергологии и иммунопатологии кожи

qwertil2010@yandex.ruhttps://orcid.org/0000-0002-5021-9276LitovkinaAlla O.ЛитовкинаАлла Олеговна
Russian Federation

Graduate student in the Department of Skin Allergy and Immunopathology

студентка

dr.litovkina@gmail.comhttps://orcid.org/0000-0002-1389-5566KolykhalovaKsenia I.КолыхаловаКсения Игоревна
Russian Federation

Student

студентка

kolykhalovaaa@yandex.ruhttps://orcid.org/0000-0002-4609-2591ElisyutinaOlga G.ЕлисютинаОльга Гурьевна
Russian Federation

Leading researcher of the Department of Skin Allergy and Immunopathology

в.н.с. отделения аллергологии и иммунопатологии кожи

el-olga@yandex.ruhttps://orcid.org/0000-0003-3358-50876603386923P-6912-20155012-7242FedenkoElena S.ФеденкоЕлена Сергеевна
Russian Federation

Head of the Department of Skin Allergy and Immunopathology

зав. отделением аллергологии и иммунопатологии кожи

efedks@gmail.comNRCI Institute of Immunology FMBA of RussiaГНЦ «Институт иммунологии» ФМБА РоссииI.M. Sechenov First Moscow State Medical University (Sechenov University)Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет)2912202017430371304202008062020Copyright ©; 2021, Pharmarus Print MediaCopyright ©; 2021, Фармарус Принт Медиа2021Pharmarus Print MediaФармарус Принт Медиаhttps://rusalljournal.ru/raj/article/view/1355

Allergic diseases are increasingly becoming a global epidemic and pose a considerable and growing public health burden. Allergy is a systemic T2-dependent inflammatory reaction to an allergen that results from a complex interaction between genetic and environmental factors. Allergic diseases occur through a T2-dependent type of allergic reaction, some of them, in particular atopic dermatitis (AD) and asthma, develop involving different types of hypersensitivity or their combination and require revision of allergy diagnostics. Atopy patch test (APT) can be informative in establishing a role of cell-mediated hypersensitivity in pathogenesis of allergic diseases.

The review presents the recent data on the significance of APT in the diagnostics of skin and respiratory allergies.

Эпидемический рост распространенности аллергических заболеваний в мире представляет большую социально-экономическую проблему. Аллергия возникает в результате сложного взаимодействия между генетическими факторами и факторами окружающей среды и является системной Т2-зависимой воспалительной реакцией на аллерген. Большинство аллергических заболеваний протекают по Т2-зависимому типу аллергических реакций. Вместе с тем в развитии некоторых заболеваний, таких как атопический дерматит (АтД) и бронхиальная астма (БА), могут лежать разные типы гиперчувствительности, что требует пересмотра алгоритмов аллергодиагностики. Атопический кожный аппликационный тест (АКАТ) может дать дополнительную информацию о возможной роли клеточно-опосредованного типа гиперчувствительности в патогенезе этих заболеваний.

В статье представлен обзор современных данных о значимости АКAT в диагностике кожной и респираторной аллергии.

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