Vol 6, No 2 (2009)

Actual level of Bronchial Asthma (BA) control is not perfect now, despite of modern effective treatment and increase in quantity of their consumption. It testifies that in addition to correction of volume of pharmacological loading for BA patients the account of negative influence of external factors (allergens, an infection) and correction of the comorbidities which potentially worsening an asthma condition is necessary. Besides, there are different ways for an estimation of a condition of BA control: based as on objective datas (ventilation parameters, sputum eosinophilia, tests for airway hyperreactivity) and the subjective data (the various questionnaires filled with patients) are used. The analysis of the reasons for full BA control absence in the majority of patients and search of an optimum combination for an estimation of a condition of patients with BA is an actual problem of modern medicine.

The aim of the study. To study 26 kinds of medicinal vegetative raw material to reveal their antianaphy lactic activity. Materials and methods. Comparative studying of antianaphylactic activity of vegetative objects was carried out with use of ovalbumin models of systemic anaphylactic shock and passive skin anaphylaxis. Results. All kinds of the investigated vegetative raw material had a suppressing action on the development and the degree of suppression the passive skin anaphylaxis. The most active were liquorices, leaves of a birch, cowberry, nettle, mint, walnut, tea green, St.-Gohn's wort, horsetail herb, hop cones, linden flowers, chamomile flowers, styles with stigmata of maydays. The influence of water extractions on the development of system anaphylactic shock has been shown, as well as some vegetative objects extended the time of beginning anaphylactic reactions and reduced the degree of their expressiveness. The most active were liquorices, leaves of birch, cowberry, nettle, mint, walnut, grass of violet, horsetail, hop cones and lindens flowers. The conclusion. Liquorices, leaves of birch, nettle, mint, walnut, tea green, grass of horsetail, violet, styles with stigmata of maydays possess antianaphylactic activity

In this article the authors represent data of self experience of new method of parasites examination - histocoprology used in 192 allergodermatoses patients and the efficacy of antihelminthic treatment.

According to the statistics data about 40% of the population of the world suffer from allergic diseases. A variety of the factors participate in activation and formation of allergic illnesses, assume the use of a wide spectrum of medical products for correction and changes arising at an allergic inflammation. It is necessary to note that a basis of treatment of these diseases is preventive maintenance. We will stop in detail at the group of preparations of cromoglicate acid, which is widely used in clinical practice for prevention of exacebrations and treatment of allergic diseases. Some features of cromons such as a high profile ofsafety, good tolerance, possibility of long using in pediatrics and during pregnancy, low system bioavailability and economic advisability will be discussed.

Цель. Оценить клиническую эффективность и безопасность препарата эбастин 20 мг у больных атопическим дерматитом (АтД) в сочетании с круглогодичным аллергическим ринитом (КАР). Материалы и методы. Под наблюдением находилось 20 больных с АтД с признаками КАР в возрасте от 18 до 46 лет. Длительность курса лечения эбастином 20 мг в комплексной терапии АтД и КАР составляла 21 день. Больные принимали препарат в таблетках по 20 мг 1 раз в день. Оценка эффективности лечения проводилась до начала приема эбастина (0 день), в течение курса лечения (7- и 14-й дни) и после курса лечения (22-й день). Результаты. На фоне проведенной терапии отмечено достоверное уменьшение индекса SCORAD во всех исследуемых группах. Также отмечено уменьшение индекса респираторных симптомов. Заключение. Препарат эбастин 20 мг является эффективным антигистаминным средством, как в отношении симптомов аллергического ринита, так и основных симптомов АтД, включая кожный зуд.