Reasons and mechanisms of organ remodeling in kidney, cardiovascular diseases and bronchialasthma



Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Organ and system remodeling is a very common process and is observed in some kidney, cardiovascular, GI, liver diseases and bronchial asthma. Main mechanism is tissue fibrosis in organs with excessive function.

About the authors

V I Pytsky

References

  1. Фрейдлин И.С, Соколов Д.И. Кооперативные эффекты цитокинов. Конгресс РААКИ, М., 2001 (1), с. 311-324.
  2. Wolf G. Angiotensin II: a pivotal factor in the progression of renal diseases. Nephrol. Dial. Transplant. 1999, v. 14 (1), p. 41-44.
  3. Liu J. Renal fibrosis: new insights into the pathogenesis and therapeutics. Kindey Int. 2006, v. 69, p. 213-217.
  4. Ruiz-Ortega M., RuperezM., EstebanV, Rodriguez-vita J.. Angiotensin II: a kay factor in the inflammatory and fibrotic response in kidney diseases. Nephrol. Dial. Transplant. 2006, v. 21, p. 12-20.
  5. Negri AL. Prevention of progressive fibrosis in chronic renal diseases: antifibiotic agents. J. Nephrol. 2004, v. 17, p. 496-503.
  6. Danielson L.A, Welford A., Harris A. Relaxin improves renal function and histology in aging Munich Wistar rats. J.Am. Soc. Nephrol. 2006, v. 17, p. 1325-1333.
  7. Арутюнов Г.П., Костюкевич О.И. Морфофункциональные изменения тонкой кишки у больныхс хронической сердечной недостаточностью. Тер. Архив. 2004, № 2, с. 40-44.
  8. Matsusaka Т, Katori Н., Miyazaki et al. Angiotensin II as a player in fibrosis. Nephrol. Dial. Transplant. 2000, v. 15 (6), p. 64-65.
  9. Nunez Е., Hosoya К., Susik D., Frohlich D. Enalapril and losartan reduced mass and improved coronary hemodynamics in SHR. Hypertension. 1997, v. 29 (2), p. 519-524.
  10. Kim S., Zhan Yu., Izumi Ya., Iwao H. Cardiovascular effects of combination of perindopril, candesartan, and amlodipine in hypertensive rats. Hypertension. 2000, v. 35, p. 769-774.
  11. Овчинников А.Г., СербулВ.М., Агеев Ф.Т. Влияние блокаторов ренин-ангиотензивной системы на гипертрофию левого желудочка и биохимические маркеры баланса коллагена у больных с гипертонической гипертрофией Тер. Архив. 2009, № 5, с. 64-70.
  12. Shu Hashimoto, Ken Matsumoto Yasuhiro Gon, Toshio Ichivata et al. Update on Airway Inflammation and Remodeling in Asthma. Allergy Clin. Immunol Int. J. World Allergy Org. 2007, v. 19 (5), p. 178-184.
  13. Barbato A, Turato G. Barlso S. et al. Airway Inflammation in childhood asthma. Am. J. Respir. Crit Care-med. 2003, v. 168, p. 789-803.
  14. Saglany S., Malmstrom K., Pelconene A.S. et al. Airway remodeling and inflammation in symptomatic infants with reversible airflow obstruction Am. J. Respir. Crit Care Med. 2005, v. 171, p. 722-777.
  15. Martinez F.D., MorganW.J., Wright A.L., HolbergC.J., Taussing U.M. Diminished lung function as a predisposing factor for wheezing respiratory illness in infants. New Engl. J. Med. 1988, v. 319, p. 1112-1117.
  16. Holgate S.T, Davies D.E. Воспаление дыхательных путей и структурные изменения их стенок - причина или следствие? Астма. 2001, т. 2, № 1, с. 9-16.
  17. Lew D.B., Lieberman P. Lung remodeling in asthma Allergy Clin. Immunol. Intern. 2003, v. 15 (1), p. 4-10.
  18. Scow CY, Schellenberg R.R., Pare P.D. Structural and functional changes in the airway smooth muscle of asthmatic subjects. Am. J. Respir. Crit. Care Med. 1998, v. 158, p. 179-186.
  19. Brightling C.F., Bradding P., Symon F.A, Holgate S.T et al. Mast cell infiltration of airway smooth muscle in asthma. New Engl. J. Med. 2002, v. 346 (22), p. 1699-1705.
  20. Vrugt В., Wilson S., Bronchihi A, Holgate S.T. Bronchial angiogenesis in severe glucocorticoid-dependent asthma. Eur. respir. J. 2000, v. 45, p. 1014-1021.
  21. Глобальная стратегия лечения и профилактики бронхиальной астмы. Перевод с англ. Пересмотр 2002 г. Москва, Изд. «Атмосфера». 2002 г., 160 с.
  22. Мейл Д., Бростофф Дж., Рот Д.Б., Ройт А. Иммунология. М., Изд. «Логосфера». 2007, 556 с.
  23. Пыцкий В.И. Механизмы возникновения и развития бронхиальных астм и основные принципы их лечения. М., «Фармарус Принт Медиа». 2008, 54 с.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright © Pharmarus Print Media, 2009



This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies