Email this article 
The level of immunoglobulin E in patients with pyoinflammatory diseases
- Authors: Druzhinina TA1, Alekseeva NU1, Molotilov BA1, Ivachov AS1, Peskov AV1
-
Affiliations:
- The state educational institution of additional vocational training «The Penza institute of advanced medical studies» of The Federal public health and social development agency
- Issue: Vol 7, No 2 (2010)
- Pages: 23-27
- Section: Articles
- URL: https://rusalljournal.ru/raj/article/view/872
- DOI: https://doi.org/10.36691/RJA872
- ID: 872
Cite item
Open Access
Access granted
Subscription or Fee Access
Abstract
pyoinplammatory diseases.
Materials and methods. 80 patients with acute appendicitis, 51 patients with chronic recurrent furunculosis, 27
patients with chronic osteomyelitis aged 16 to 60 years old have been examined. The patients with the increased
IgE level underwent clinical and allergologycal assessment. Patients with chronic pyoinplammatory diseases
had been skin tested with the Staphylococcus aureus allergens.
Results. Total IgE level was increased in all nosologic groups of patients. In patients with the increased IgE level
atopy or antihelminths antibodies have been established. In patients with chronic pyoinflammatory total IgE
level was not changed but negative correlative connections between the level of immunoglobulin and the late
phase of immediate hypersensitivity reaction have been shown. Increased level of serum immunoglobulin E in
patients with acute appendicitis confirmed more serious involvement of appendix and surrounding tissues and
the higher indexes of white blood cells count before the operation.
Conclusion. Increased IgE level in patients with pyoinflammatory diseases reflects Th2 type of immune response
mostly due to the condition of atopy or parasites. The higher rate of development of destructive and complicated
forms of appendicitis is typical for the patients with acute appendicitis and the increased IgE level.
Keywords
About the authors
T A Druzhinina
The state educational institution of additional vocational training «The Penza institute of advanced medical studies» of The Federal public health and social development agency
Email: giuv@penza.ru
The state educational institution of additional vocational training «The Penza institute of advanced medical studies» of The Federal public health and social development agency
N U Alekseeva
The state educational institution of additional vocational training «The Penza institute of advanced medical studies» of The Federal public health and social development agencyThe state educational institution of additional vocational training «The Penza institute of advanced medical studies» of The Federal public health and social development agency
B A Molotilov
The state educational institution of additional vocational training «The Penza institute of advanced medical studies» of The Federal public health and social development agencyThe state educational institution of additional vocational training «The Penza institute of advanced medical studies» of The Federal public health and social development agency
A S Ivachov
The state educational institution of additional vocational training «The Penza institute of advanced medical studies» of The Federal public health and social development agencyThe state educational institution of additional vocational training «The Penza institute of advanced medical studies» of The Federal public health and social development agency
A V Peskov
The state educational institution of additional vocational training «The Penza institute of advanced medical studies» of The Federal public health and social development agencyThe state educational institution of additional vocational training «The Penza institute of advanced medical studies» of The Federal public health and social development agency
References
- Азимов А.Г. О роли иммуноглобулина Е в патологии. Иммунопатология, аллергология, инфектология. 2002, № 2, с. 73-78.
- Гущин И.С. Физиология иммуноглобулина Е. Аллергология и иммунология. 2000, № 1, с. 76-86.
- Raif S. Geha, Haifa H. Jabata, Scott R. Brodeur. Регуляция механизма рекомбинации переключения на синтез иммуноглобулина Е. Аллергология и иммунология. 2005, № 1, с. 23-37.
- Железникова Г.Ф. Иммуноглобулин Е: биологическая роль при инфекционных заболеваниях. Мед. иммунол. 2002, № 4-5, с. 515-534.
- Вишневский А.А., Орлов Б.А., Тиходеев С.А. Выбор иммуномодулирующей терапии при неспецифическом остеомиелите позвоночника. Вестн. хирургии. 2006, № 2, с. 32-36.
- Дружинина ТА., Молотилов Б.А., Ивачев А.С., Баранова Н.И. Определение общего иммуноглобулина Е у больных с острым аппендицитом. Вестн. хирургии. 2001, № 2, с. 28-30.
- Сетдикова Н.Х., Латышева ТВ. Комплексные механизмы развития хронического рецидивирующего фурункулеза и пути их коррекции. Иммунология. 2000, № 3, с. 48-58.
- Суходоева Г.С, Мошкевич B.C., Каральниик Б.В., Нугманова Д.С. Аллергия к стафилококкам. Алма-Ата, «Наука», 1984, 176 с.
- Федосеева В.Н., Молотилов Б.А., Ларина О.Н., Федос-кова ТТ. Бактериальная аллергия. Пенза, 2004, 40 с. Хирургические инфекции. Под ред. Ерюхина И.А., Гельфанда Б.Р., Шляпникова С.А М., «Литтерра». 2006, 736 с.
- Гущин И. С. Аллергическое воспаление и его фармакологический контроль. М., «Фармарус Принт», 1998, 250 с.
- Пыцкий В.И. Обоснование классификации форм бронхиальной астмы и анализ их патогенеза. Астма, 2000, № 1, с. 14-26.
- Симбирцев А.С. Цитокины в иммунопатогенезе и лечении аллергии. Рос. Аллергол. Журн., 2007, № 1, с. 5-19.
- Чернышева Е.С., Моршнева Е.С. Морфологическая диагностика некоторых гельминтозов при анализе оперированных червеобразных отростков. Арх. патол., 2002, № 1, с. 37-41.
- Беклемишев Н.Д. Иммунопатология и иммунорегуляция. М., «Медицина», 1986, 256 с.
Supplementary files
