The retrospective analysis of the anamnestic, clinical and laboratory data in patients with chronicidiopathic urticaria

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Background. analysis of the anamnestic, clinical laboratory findings in patients with chronic idiopathic urticaria.
Methods. The retrospective study of the anamnestic clinical laboratory findings in patients with chronic idiopathic.
Results. women are predominant (3,4:1), 72% chronic idiopathic urticaria in the course of less or equal 5 years,
73% of patients suffer from urticaria and angioedema, triggers of urticaria are stress in 62% of patients, food in
27%, medications in 24%, acute respiratory disease in 12%, premenstrual syndrome in 6%. The part of patients
with autoimmune thyroiditis is 21%. 46% of patients had signs of autoimmune pathology. 20% have antiparasitic
antibodies. 100% of patients have gastrointestinal problems, 67% - chronic tonsillitis, 14% - atopic disease, 9% -
parasitosis. in 43% of patients H. pylori infection was found. changed parameters of bacteriological studies of
feces were detected in 85% of patients. There were no health hazard conditions.

About the authors

R N Golubchikova

I V Danilycheva

Email: ivdanilycheva@mail.ru

O Yu Rebrova

R N Golubchikova

Institute of Immunology

Institute of Immunology

I V Danilycheva

Institute of Immunology

Institute of Immunology

O Yu Rebrova

Institute of Immunology

Institute of Immunology

References

  1. Kaplan A.P. Clinical practice. Chronic urticaria and angioedema. N. Engl. J. Med. 2002, v. 30, p. 381.
  2. Zuberbier T. et al. EAACI/CA2LEN/EDF guideline: management of urticaria. Allergy. 2006, v. 61, p. 321-331.
  3. Roger W., Fox M.D. Chronic urticaria: mechanism and treatment. Allergy and Asthma proc. 2001, v. 22 (2), p. 97-100.
  4. Greaves M.W., Hussein S.H. Drug-induced urticaria and angioedema: pathomechanisms and frequencies in a developing country and in developed countries. Int. Arch. Allergy Immunol. 2002, v. 13 (1), p. 23-26.
  5. Liutu M., Kalimo K., Uksila J. Etiologic aspects of chronic urticaria. Int. J. Dermatol. 1998, v. 37 (7), p. 515-519.
  6. Gaig P., Garcia-Ortega P., Enrique E. et al. Efficacy of the eradication of Helicobacter pylori infection in patients witch chronic urticaria. A placebo-controled double blind study. Allergol. Immunol. (Madr.) 2002, v. 30, p. 255-258.
  7. Koehn G.G., Thorne E.G. Urticaria and viral hepatitis. Arch. Dermatol. 1972, v. 106, p. 422.
  8. Williams C.M., Galli S.J. The diverse potential effector and immunoregulatory rolles of mast cells in allergic disease. J. Allergy. Clin. Immunol. 2000, v. 105 (5), p. 847-859.
  9. James J., Warin R.P. An assessment of the role of Candida albicans and food yeasts in chronic urticaria. Br. J. Dermatol. 1971, v. 84, p. 227.
  10. Kikuchi Y., Fann T., Kaplan A.P. Antithyroid antiboides in chronic urticaria and angioedema. J. Allergy Clin. Immunol. 2003, v. 112 (1), p. 218.
  11. Samochocki Z. Diagnostic problem of ordinary chronic urticaria. Pol. Merkuriusz Lek. 2003, v. 14 (84), p. 557-558.
  12. Niimi N., Francis D.M., Kermani F. et al. Dermal mast cell activation by autoantibodies against the high affinity IgE receptor in chronic urticaria. J. Invest. Dermatol. 1996, v. 106, p. 1001-1006.
  13. Ferrer M., Nakazawa K., Kaplan A.P. Complement dependence of histamine release in chronic urticaria. J. Allergy Clin. Immunol. 1999, v. 104, p. 169-172.
  14. Kozel M.D., Martina M.A., Patrick M.M. et al. Laboratory tests and identified diagnoses in patients with physical and chronic urticaria and angioedema: A systematic review. J. Am. Acad. Dermatol. 2003, v. 48, p. 409-415.
  15. Ortone J.P. Chronic idiopathic urticaria for the generalist. Eur. J. Intern. Med. 2003, v. 14 (3), p. 148-157.
  16. Медицинские стандарты (протоколы) диагностики и лечения больных с аллергическими заболеваниями и нарушениями иммунной системы. Изд. 2-е (дополненное и переработанное). Под ред. Р.М. Хаитова. М., 2001, 120 c.
  17. Российский Национальный согласительный документ: Крапивница и ангиоотек: рекомендации для практических врачей. М., «Фармарус Принт Медиа». 2007, с. 68-70.
  18. Miller D.A., Freeman G.L., Akers W.A. Chronic urticaria: a clinical study of fifty patients. Am. J. Med. 1968, v. 44, p. 68-86.
  19. Trachel C., Pichler W.J., Helbling A. Importance of laboratory investigation and trigger factors in chronic urticaria. Schweiz Med. Wochenschr. 1999, v. 129, p. 1271-1279.
  20. Schnyder B., Helbling A., Pichler W.J. Chronic idiopathic urticaria: natural course and association with Helicobacter pylori infection. Int. Arch. Allergy Immunol. 1999, v. 119, p. 60-63.
  21. Wedi B., Wagner S., Werfel T.H. Prevalence of Helicobacter pylori-associated gastritis in chronic urticaria. Int. Arch. Allrgy Immunol. 1998, v. 116, p. 288-294.
  22. Meynadier J., Guilhou J.J., Lavanture N. Chronic urticaria: etiology and therapeutic evaluation of 150 cases. Ann. Dermatol. Venerol. 1979, v. 106, p. 153-158.
  23. Kleine-Natrop H.E., Sebastian G. Analyse und kritik der urticaria-diagnostik. Dermatol. Monatsschr. 1973, v. 159, p. 769-778.
  24. Schultz-Ehrenberg U., Gilde O. Results of examination in chronic urticaria with special consideration of nutrition factors. Z. Hautkr. 1987 (suppl 1), p. 88-95; Jacobson MKW.,Branch L.B., Nelson H.S. Laboratory tests in chronic urticaria.JAMA. 1980, v. 243, p. 1644-1646.
  25. Pigatto P.D., Valsecchi R.N. Chronic urticaria: a mystery. Allergy. 2000, v. 55, p. 306-308.
  26. Small P., Barrett D.,Biskin N., Champlin E. Chronic urticaria and angioedema. Clin. Allergy. 1982, v. 12, p. 131-136.
  27. Zuberbier T., Maurer M. Urticaria: Current Opinions about Etiology, Diagnosis and Therapy. Acta Derm. Venerol. 2007, v. 87, p. 196-205.
  28. Тиц Н. Клиническое руководство по лабораторным тестам. М., «Юнимед-пресс». 2003.
  29. Zuberbier T. et al. EAACI/CA2LEN/EDF guideline: definition, сlassification and diagnosis of urticaria. Allergy. 2006, v. 61, p. 316-320.
  30. http://www.graphpad.com/quickcalcs/ConfInterval2.cfm. Agresti. A., Coull B.A. Approximate is better than «Exact» for interval estimation of binomial proportion. The American Statistician. 1998, c. 52, p. 119-126.
  31. Реброва О.Ю. Статистический анализ медицинских данных. М., «Медиа Сфера». 2006, c. 157-159.
  32. Реброва О.Ю. Статистический анализ медицинских данных. М., «Медиа Сфера». 2006, c. 83-91.
  33. Ляпин С.В., Тотолян А.А. Антинуклеарные антитела: лабораторные тесты и диагностическое значение. Мед. иммунол. 2001, № 1, с. 35-50.
  34. Потехин О.Е., Малышев В.С. Современное состояние иммунологической диагностики аутоиммунных заболеваний. Иммунол., аллергол., инфектол. 2000, № 1, с. 44-49.
  35. Buss Y.A. et al. Chronic urticaria - which clinical parameters are pathogenetically relevant? A retrospective investigation of 339 patients. JDDG. 2007, v. 1, p. 22-27.
  36. Silvares M.R.C. et al. Sociodemographic and clinical characteristics, causal factors and evolution of a group of patients with chronic urticaria-angioedema, San Paulo Med. J. 2007, v. 125.
  37. Toubi E., Kessel A., Avshovich N. Clinical and laboratory parameters in predicting chronic urticaria duration: a prospective study of 139 patients. Allergy. 2004, v. 59, p. 896-873.
  38. Kozel M.M., Ansari Moein M.C., Mekkes J.R. et al. Evaluation of a clinical guideline for the diagnoses of physical and chronic urticaria and angioedema. Acta Derm. Venerol. 2002, v. 82, p. 270-274.
  39. Kozel M.M., Mekkes J.R., Bossuyt P.M.M., Bos J.D. The effectiveness of history-based diagnostic approach in chronic urticaria and angioedrma. Arch. Dermatol. 1998, v. 134, p. 1575-1580.
  40. Champion R.H., Highet A.S. Investigation and management of chronic urticaria and angioedema. Clin. Exp. Dermatol. 1982, v. 7, p. 291-300.
  41. Ormerod A.D. Urticaria and angioedema. BMJ. 1984; 289:903-6; Juhlin L. Additives in chronic urticaria. Ann. Allergy. 1987, v. 59, p. 119-123.
  42. Soter N.A. Acute and chronic urticaria and angioedema. J. Am. Acad. Dermatol. 1991, v. 25, p. 146-154.
  43. Wanderer A.A., Bernstein I.L., Goodman D.L. et al. The diagnosis and management of urticaria: a practice parameter part II: chronic urticaria/angioedema. Ann. Allergy Asthma Immunol. 2000, v. 85, p. 532-544.
  44. Zuberbier T., Greaves M.W., Juhlin L. et al. Definition, classification and routine diagnosis of urticaria: a consensus report. J. Invest. Dermatol. Symp. Proc. 2001, v. 6, p. 123-127.
  45. Козинец Г.И., Макарова В.А. Исследования системы крови в клинической практике. М., «Триада Х». 1997.
  46. Hidvegi B., Nagy E., Szabo T. et al. Correlation between N-cells and mast cell activity in patients with chronic urticaria. Int. Arch. Allergy Immunol. 2003, v. 132 (2), p. 177.
  47. Zauli D., Deleonardi G., Grassi A. et al. Thyroid autoimmunity in chronic urticaria. Allergy Asthma Proc. 2001, v. 22 (2), p. 93-95.
  48. Гервазиева В.Б., Сверановская В.В., Сибгатулина Н.А. Патогенетические механизмы хронической крапивницы. Вестн. РАМН. 2003, № 4, с. 49-53.
  49. Сибгатулина Н.А. Клинико-иммунологические особенности хронической рецидивирующей крапивницы и методы ее диагностики. Автореферат диссертации канд. мед. наук. М., 2003, 27 с.
  50. Вeltrani V.S. An overview of chronic urticaria. Clin. Rev. Allergy Immunol. 2002, v. 32 (2), p. 147-169.
  51. Wai Y.C., Sussman G.L. Evaluating chronic urticaria patients for allergies, infections, or autoimmune disordes. Clin. Rev. Allergy Immunol. 2003, v. 130, p. 1115-1118.

Statistics

Views

Abstract: 127

Article Metrics

Metrics Loading ...

Dimensions

PlumX


Copyright © Pharmarus Print Media, 2011



This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies