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The problems of clinical efficiency and safety of application of tacrolimus (Protopik) at various skin diseases are discussed in this review. High efficiency of this drug, allows to use it in treatment of different dermatosis. The clinical effect is comparable with topical corticosteroids, and the rate of adverse effects is lower. It is possible to use long applications of calcineurin inhibitors in patients with resistant forms of atopic dermatitis. Positive effects of application of tacrolimus in vitiligo, balanitis, alopecia areata etc. are described.

About the authors

S A Ochelenko

Email: ochelenko-v@yandex.ru <mailto:ochelenko-v@yandex.ru>

K N Monakhov

S A Ochelenko

Рavlov State Мedical University of St .Petersburg

Рavlov State Мedical University of St .Petersburg

K N Monakhov

Рavlov State Мedical University of St .Petersburg

Рavlov State Мedical University of St .Petersburg


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