Email this article 
Levocetirizine in allergic rhinitis and rhinoconjunctivitis treatment(review)
- Authors: Lopatin AS1, Latysheva EN1, Lopatin AS2, Latisheva EN2
-
Affiliations:
- First Moscow State Medical University named after Setchenov, ENT Devision
- Issue: Vol 8, No 6 (2011)
- Pages: 47-52
- Section: Articles
- URL: https://rusalljournal.ru/raj/article/view/807
- DOI: https://doi.org/10.36691/RJA807
- ID: 807
Cite item
Open Access
Access granted
Subscription or Fee Access
Abstract
This review is devoted to efficacy and safety of levocetirizine in allergic rhinitis treatment. Levocetirize has been
shown to be able to control all symptoms of allergic rhinitis including nasal obstruction, it has anti-inflammatory
and immunomodulatory activity. Levocetirizine has been proven to be safe even in long-term administration
and has less adverse reactions in comparison with other antihistamine drugs. So, levocetirizine is efficacious
and safe medication for treatment patients with mild-to-moderate seasonal and perennial allergic rhinitis and
rhinoconjunctivitis.
shown to be able to control all symptoms of allergic rhinitis including nasal obstruction, it has anti-inflammatory
and immunomodulatory activity. Levocetirizine has been proven to be safe even in long-term administration
and has less adverse reactions in comparison with other antihistamine drugs. So, levocetirizine is efficacious
and safe medication for treatment patients with mild-to-moderate seasonal and perennial allergic rhinitis and
rhinoconjunctivitis.
Keywords
About the authors
A S Lopatin
Email: lopatin@lor.ru
E N Latysheva
A S Lopatin
First Moscow State Medical University named after Setchenov, ENT DevisionFirst Moscow State Medical University named after Setchenov, ENT Devision
E N Latisheva
First Moscow State Medical University named after Setchenov, ENT DevisionFirst Moscow State Medical University named after Setchenov, ENT Devision
References
- Sibbald В., Rink E. Epidemiology of seasonal and perennial rhinitis: clinical presentation and medical history. Thorax. 1991, v. 46, p. 895-901.
- Katelaris C.H., Lee B W., Potter P. С., Maspero J.F., Cingi C., Lopatin A. et al. Prevalence and diversity of allergic rhinitis in regions ofthe world beyond Europe and North America. Clin. Exp. Allergy. 2011 (в печати).
- Лопатин А.С. Ринит. М., «Литтерра». 2010.
- ARIA. Allergic rhinitis and its impact on asthma. WHO initiative, 2001.
- Гущин И.С. Аллергическое воспаление и его фармакологический контроль. М., «Фармарус Принт». 1998, 252 с.
- Ciprandi G., Cirillo I., Vizzaccaro A., Tosca M.A. Levocetirizine improves nasal obstruction and modulates cytokine pattern in patients with seasonal allergic rhinitis: a pilot study Clin. Exp. Allergy. 2004, v. 34, p. 958-964.
- Ciprandi G., Cirillo I., Vizzaccaro A., Civardi E. et al. Dezloratadine and levocetirizine improve nasal symptoms, airflow, and allergic inflammation in patients with perennialallergic rhinitis: A pilot study. International Immunopharmacology 2005, v. 5, p. 1800-1808.
- Mahmound F., Arifhodzic N., Haines D., Novotney L. Levocetirizine modulates lymphocyte activation in patients with allergic rhinitis. J. Pharmacol. Sci. 2008, v. 108, p. 149-156.
- Day J.H., Briscoe M.R., Rafeiro E., Ratz J.D. Comparative clinical efficacy, onset and duration of action levocetirizine and dezloratadine for symptoms of seasonal allergic rhinitis in subject evaluated in the Environmental Exposure Unit (EEU). Int. J. Clin. Pract. 2004, v. 58, 2, p. 109-118.
- Jorissen M., Bertrand B., Stiels B., Vandenbulcke K. Levocetirizine as treatment for symptoms of seasonal allergic rhinitis. B-ENT 2006, v. 2, p. 55-62.
- Canonica G.W., Fumagalli F., Guerra L., Baiardini I. et al. Levocetirizine in persistent allergic rhinitis: continuos or on-demand use? A pilot study. Current medical research and opinion. 2008, v. 24, 10, p. 2829-2839.
- Lombardo G., Quattrocchi P., Lombardo G.R., Galati P. et al. Concomitant levocetirizine and montelukast in the treatment of seasonal allergic rhinitis: influence on clinical symptoms. J. Allergy Clin. Immunol. 2006, v. 16, p. 63-68.
- Patel P., Patel D. Efficacy comparison of levocetirizine vs montelucast in ragweed sensitized patients. Ann. Allergy Asthma Immunol. 2008, v. 101, p. 287-294.
Supplementary files
