DECLINE DYNAMICS OF STAHPYLOCOCCUS AUREUS SUSCEPTIBILITY TO ANTIBIOTICS IN CHILDREN WITH ATOPICDERMATITIS



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Abstract

Background. Staphylococus aureus (S. aureus) colonization is revealed in 87-90% patients with atopic dermatitis
(aD). S. aureus antibiotic susceptibility differs within time. the study is aimed to investigate the dynamics of
S.aureus susceptibility to antibiotics and time limitation of this process in children with aD.
Methods. S. aureus susceptibility to 19 antibiotics was analyzed with 72 resistance patterns (31 initial and 41 repeated
in 0,5-30 months) of 203 performed in 647 children with aD tested in 2007-2009 years.
results. in a three year period (2007-2009) a negative correlation of S. aureus antibiotic susceptible strains prevalence
versus months since initial pattern was revealed (R=−0,29 p<0,01; г=−0,29, p<0,003; ф=−0,23 p<0,003). prevalence of
antibiotic susceptible strains prevailed initially more than two times over resistant one has become not reliable in 12
months.
conclusion. a child with aD is needed to be set and clear up with anti-inflammatory and antibacterial therapy in a 12
months period past hospital check-up. the decrease of S. aureus antibiotic susceptible strains within this period could
probably reduce the effect of the following antibacterial therapy.

About the authors

M S Treneva

A N Pampura

Z V Zaporozhtseva

M S Treneva

Federal state institution «Moscow Science Research Institute of pediatrics and child surgery by Federal agency of advanced technology medical help»

Federal state institution «Moscow Science Research Institute of pediatrics and child surgery by Federal agency of advanced technology medical help»

A N Pampura

Federal state institution «Moscow Science Research Institute of pediatrics and child surgery by Federal agency of advanced technology medical help»

Federal state institution «Moscow Science Research Institute of pediatrics and child surgery by Federal agency of advanced technology medical help»

Z V Zaporozhtseva

Federal state institution «Moscow Science Research Institute of pediatrics and child surgery by Federal agency of advanced technology medical help»

Federal state institution «Moscow Science Research Institute of pediatrics and child surgery by Federal agency of advanced technology medical help»

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