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Background. To study informativeness, clinical significance and relationship between objective and subjective methods of assessing asthma control and creation an optimal algorithm.
Methods. The study involved 40 patients of both sex, aged from 18 to 75 years old suffering from persistent, moderate and severe asthma , having no control.
Results. All patients were assessed asthma control using methods based on subjective data (medical history, filling the questionnaires: the ACT and AQLQ; survey on the presence of comorbidity) and objective methods of examination (auscultation, PEV, spirometry, ECP in blood, content of eosinophils in induced sputum and peripheral blood). All patients were assigned to anti-asthma therapy combination therapy (ICS+LABA). The main reasons for lack of asthma control is the inadequacy of basic therapy and concomitant diseases. Symptoms and normalization of ERF occur much earlier (on day 30 of therapy) than the relief of bronchial inflammation. Adequate methods to assess asthma control are objective methods, subjective can only be used as an extra.
Conclusion. The analysis of the causes of asthma control in each individual case, increased medical supervision over appointments and continuous monitoring by means of subjective and objective ways of assessing control, avoid excessive use of pharmaceutical loads, to minimize the side effects of treatment, faster to achieve better results by optimizing costs treatment.

About the authors

E V Nazarova

Oksana Mikhaylovna Kurbacheva

Email: <>

N I Il'ina

E V Nazarova

Institute of immunology, Moscow, Russia

Institute of immunology, Moscow, Russia

O M Kurbacheva

Institute of immunology, Moscow, Russia

Institute of immunology, Moscow, Russia

N I Ilina

Institute of immunology, Moscow, Russia

Institute of immunology, Moscow, Russia


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