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Assessment of Rosaceae sensitisation diagnostics in allergic children
- Authors: Pampura AN1, Konjukova NG1, Fedenko ES2, Havkin AI1, Okuneva TS1
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Affiliations:
- Moscow Research Institute of Pediatric and Child Surgery
- Institute of Immunology
- Issue: Vol 9, No 1 (2012)
- Pages: 66-72
- Section: Articles
- Submitted: 10.03.2020
- Published: 15.12.2012
- URL: https://rusalljournal.ru/raj/article/view/732
- DOI: https://doi.org/10.36691/RJA732
- ID: 732
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Abstract
Background. Sensitization to the fruits of the family Rosaceae is widespread in children population, but its diagnostics is often difficult. Methods. The study included 190 children with suspected allergy to the fruit family of Rosaceae. Results. The presence of sensitization was found in 148 patients. Qualitatively, the results of in vitro and in vivo tests with allergens differed approximately one third of cases. Among children with sensitization to the fruits of a family Rosaceae specific IgE to rBet v 1 was identified approximately in 3/4, rPru p 3 — in 2/3, rBet v 2 — in 1/5 of patients. Conclusion. The results indicate a high informative determination of specific IgE (ImmunoCap, Phadia AB) to the fruits of Rosaceae (apple, pear, peach) and a recombinant allergens (rBet v 1, rBet v 2, rPru p 3).
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About the authors
A N Pampura
Moscow Research Institute of Pediatric and Child Surgery
Email: apampura@pedklin.ru
Russia
N G Konjukova
Moscow Research Institute of Pediatric and Child SurgeryRussia
E S Fedenko
Institute of ImmunologyMoskow, Russia
A I Havkin
Moscow Research Institute of Pediatric and Child SurgeryRussia
T S Okuneva
Moscow Research Institute of Pediatric and Child SurgeryRussia
References
- Боровик Т.Э., Скворцова В.А., Семенова Т.Т. и соавт. Эффективность фруктовых соков и пюре в питании детей раннего возраста с пищевой аллергией. Рос. вестн. перинатол. и педиатрии. 2010, № 3, с. 94-99.
- Витеу Р., Summeгs C., Chinn S. et al. Ргеvalеnсе and distri-bution of sensitization to foods in the Euгopean Community Respirator Health Survey: a EuгoPrevall analysis. Allergy. 2010, v. 65, p. 1182-1188.
- International Union of Immunological Societies Allergen Nomenclature: IUIS official list http://www.allergen.org/search. php?allergensource.
- Marzban G., Puehringer H., Dey R. et al. Localization and distribution of the major allergens in apple fruits. Plant Sci. 2005, v. 169 (2), p. 387-394.
- Hsieh L.S., Moos M. Jr., Lin Y Characterization of apple 18 and 31 kd allergens by micro sequencing and evaluation of their content during storage and ripening. J. Allergy Clin. Immunol. 1995, v. 96 (6 Pt 1), p. 960-970.
- Vieths S., Schoening B., Jankiewicz A. Occurrence of IgE binding allergens during ripening of apple fruits. Food Agric Immunol. 1993, v. 5, p. 93-105.
- Vieths S., Jankiewicz A., Schoning B., Aulepp H. Apple allergy: the IgE-binding potency of apple strains is related to the occurrence of the 18-kDa allergen. Allergy. 1994, v. 49 (4), p. 262-271.
- De Groot H., de Jong N.W, Vuijk M.H., Gerth van Wijk R. Birch pollinosis and atopy caused by apple, peach, and hazelnut; comparison of three extraction procedures with two apple strains. Allergy. 1996, v. 51 (10), p. 712-718.
- Elfman L., Svensson M., Lidholm J. et al. Different profiles in specific IgE to rBet v 1 and rBet v 2 in patients allergic to birch pollen from six countries. Int. Arch. Allergy Immunol. 1997, v. 113 (1-3), p. 249-251.
- Мокроносова М.А., Сергеев А.В., Коровкина Е.С., Ко-нюкова Н.Г Выявление IgE-антител к рекомбинантным аллергенам rBet v 1 и rBet v 2 у больных с сенсибилизацией к пыльце березы. Рос. Аллергол. Журн. 2011, № 4, с. 45-48.
- Wensing M., Akkerdaas J.H., van Leeuwen W.A. et al. IgE to Bet v 1 and profilin: cross-reactivity patterns and clinical relevance. J. Allergy Clin. Immunol. 2002, v. 110, p. 435-442.
- Schmid-Grendelmeier P. Recombinant allergens. For routine use or still only science? Hautarzt. 2010, v. 61 (11), p. 946-953.
- Gonzalez-Mancebo E., Fernandez-Rivas M. Outcome and safety of double-blind, placebo-controlled food challenges in 111 patients sensitized to lipid transfer proteins. J. Allergy Clin. Immunol. 2008, v. 121, p. 1507-1508.
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