Assessment of Rosaceae sensitisation diagnostics in allergic children

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Abstract

Background. Sensitization to the fruits of the family Rosaceae is widespread in children population, but its diagnostics is often difficult. Methods. The study included 190 children with suspected allergy to the fruit family of Rosaceae. Results. The presence of sensitization was found in 148 patients. Qualitatively, the results of in vitro and in vivo tests with allergens differed approximately one third of cases. Among children with sensitization to the fruits of a family Rosaceae specific IgE to rBet v 1 was identified approximately in 3/4, rPru p 3 — in 2/3, rBet v 2 — in 1/5 of patients. Conclusion. The results indicate a high informative determination of specific IgE (ImmunoCap, Phadia AB) to the fruits of Rosaceae (apple, pear, peach) and a recombinant allergens (rBet v 1, rBet v 2, rPru p 3).

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About the authors

A N Pampura

Moscow Research Institute of Pediatric and Child Surgery

Email: apampura@pedklin.ru
Russia

N G Konjukova

Moscow Research Institute of Pediatric and Child Surgery

Russia

E S Fedenko

Institute of Immunology

Moskow, Russia

A I Havkin

Moscow Research Institute of Pediatric and Child Surgery

Russia

T S Okuneva

Moscow Research Institute of Pediatric and Child Surgery

Russia

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