Skin microflora in atopic dermatitis patients and treatment of it's complications
- Authors: Voronina VR1, Pampura AN1, Fedenko ES1, Voronina VR1, N P.1, Fedenko ES1
-
Affiliations:
- Issue: Vol 4, No 3 (2007)
- Pages: 3-11
- Section: Articles
- Submitted: 10.03.2020
- Published: 15.09.2007
- URL: https://rusalljournal.ru/raj/article/view/61
- DOI: https://doi.org/10.36691/RJA61
- ID: 61
Cite item
Abstract
The digest is dedicated to the influence of skin microflora and secondary skin infections on atopic dermatitis clinical course. It covers the influence of St. aureus on allergic inflammation in atopic dermatitis. The digest shows the data of pyoderma clinical features and therapy solutions in patients with this disorder.
Keywords
References
- Leung D.Y.M. Atopic dermatitis: New insights and opportunities for therapeutic intervention. J. Allergy Clin. Immunol., 2000, v. 105 (5), p. 860-76.
- Мокроносова М.А. Влияние золотистого стафилококка и дрожжеподобных грибов на течение атопического дерматита. Диссертация докт. мед. наук. М., 1999.
- Елисютина О.Г., Феденко Е.С. Роль Staphylococcus aureus в патогенезе атопического дерматита. Рос. аллергол. журн., 2004, № 1, с. 17-21.
- Нобл У.К. Микроэкология кожи человека. Пер. с англ., М., «Медицина», 1986, 493 с.
- Клемпарская Н.Н. Изменения микрофлоры кожи при действии на организм экзогенных и эндогенных факторов. Материалы научно-практической конференции «Микрофлора кожи человека - ее клинико-диагностическое значение», М., 1989, с. 3-11.
- Иванов А.А. Микроэкология кожи человека и взаимосвязь с иммунным статусом организма. Материалы научно-практической конференции «Микрофлора кожи человека - ее клинико-диагностическое значение», М., 1989, с. 3-11.
- Солнцева В.К., Быков А.С., Воробьев А.А. и соавт. К вопросу микробиоценоза кожи больных хроническими дерматозами. Российский журнал кожных и венерических болезней, 2000, № 5, с. 28-31.
- Brook I., Frazier E.H., Yeager J.K. Microbiology of infected atopic dermatitis. Intern. J. Dermatology, 1996, v. 35 (11), p. 791-793.
- Ohnishi Y., Okino N., Ito M, Imayama S. Ceramidase activity in bacterial skin flora as a possible cause of ceramide deficiency in atopic dermatitis. Clin. Diagn. Lab. Immunol., 1999, v. 6 (1), p. 101-104.
- Abeck D., Mempel M. Staphylococcus aureus colonization in atopic dermatitis and its therapeutic implications. Br. J. Dermatol., 1998, v. 139, p. 13-16.
- Leyden J.E., Marples R.R., Kligmann A.M. Staphylococcus aureus in the lesions of atopic dermatitis. Br. J. Dermatol., 1974, v. 90, p. 525-530.
- Ricci G., Patrici A., Neri I. et al. Frequency and clinical role of Staphylococcus aureus overinfection in atopic dermatitis in children. Pediatr. Dermatol., 2003, v. 20 (5), p. 389-392.
- Monti G., Tonetto P., Oggero R. Staphylococcus aureus colonization in infants with atopic dermatitis. Dermatology, 1996, v. 193 (2), p. 83-87.
- Aly R. Microflora of atopic dermatitis. Arch. Derm., 1977, v. 113 (6), p. 780-782.
- Мокроносова М.А., Максимова А.Е., Батуро А.П. и соавт. Значение колонизации кожи Staphylococcus aureus для дифференциальной диагностики атопического дерматита. Вестник дерматологии и венерологии, 1997, № 5, с. 37-39.
- David T.J., Cambridge G.C. Bacterial infection and atopic eczema. Arch. Dis. Child., 1986, v. 1, p. 20-23.
- Szakos E., Lakos G. Aleksza M. et al. Relationship between skin bacterial colonization and the occurrence of allergen-specific and non-allergen-specific antibodies in sera of children with atopic eczema/dermatitis syndrome. Acta Derm. Venereol., 2004, v. 84 (1), p. 32-36.
- Neuber K., Konig W., Ring I. Staphylococcus aureus und atopisches ekzem. Hautartzt, 1993, v. 44, p. 135-142.
- Williams R.E.A., Mac Kie R.M. The staphylococci: importance of their controlling the management of skin disease. Dermatol. Clin., 1993, v. 11, p. 201-206.
- Mempel M., Schmidt T. , Weidinger S. et al. Role of Staphylococcus aureus surface-associated proteins in the attachment to cultured NaCaT keratinocytes in a new adhesion assay. J. Invest. Dermatol., 1998, v. 111 (3), p. 452-456.
- Rippke F., Schreiner V., Doering T. , Maibach H.I. Stratum corneum pH in atopic dermatitis: impact on skin barrier function and colonization with Staphylococcus aureus. Am. J. Clin. Dermatol., 2004, v. 5 (4), p. 217-223.
- Arikawa J. Decreased levels of sphingosine, a natural antimicrobial agent, may be associated with vulnerability of the stratum corneum from patients with atopic dermatitis to colonization by Staphylococcus aureus. J. Invest Dermatol., 2002, v. 119 (2), p. 433-439.
- Ong P.Y. Endogenous antimicrobial peptides and skin infections in atopic dermatitis. Engl. J. Med., 2002, v. 347 (15), p. 1151-1160.
- Imayama S., Shimozono Y., Hoashi M. et al. Reduced secretion of IgA to skin surface of patients with atopic dermatitis. J. Allergy Clin. Immunol., 1994, v. 94 (2 Pt 1), p. 195-200.
- Cho S.H., Strickland J., Boguniewicz M., Leung D.Y.M. Fibronectin and fibrinogen contribute to the enhanced binding of Staphylococcus aureus to atopic skin. J. of Allergy and Clin. Immunol., 2001, v. 108 (2), p. 269-274.
- Cho S.H., Strickland I., Tomkinson A. et al. Preferential binding of Staphy-lococcus aureus to skin sites of Th2-mediated inflammation in a murine model. J. Invest Dermatol., 2001, v. 116 (5), p. 658-663.
- Коротяев А.И., Бабичев С. А. Медицинская микробиология, иммунология и вирусология. Учебник для мед. вузов. СПб, «Специальная литература», 1998, 580 с.
- Neuber K., Konig W. Effects of Staphylococcus aureus cell wall products (teichoic acid, peptidoglycan) and enterotoxin B on immunoglobulin (IgE, IgA, IgG) synthesis and CD23 expression in patients with atopic dermatitis. Immunology, 1992, v. 75 (1), p. 23-28.
- Campbell D.E., Kemp A.S. Production of antibodies to staphylococcal superantigen in atopic dermatitis. Arch. Dis. Child., 1998, v. 79 (5), p. 400-404.
- Leung D.Y.M. Atopic dermatitis and the immune system: the role of superantigens and bacteria. J. Am. Acad. Dermatol., 2001, v. 45 (1 Suppl), p. 13-16.
- Taskapan M.O., Kumar P. Role of staphylococcal superantigens in atopic dermatitis: from colonization to inflammation. Ann. Allergy Asthma Immunol., 2000, v. 84, p. 3-10.
- Bunikowski R., Mielke M.E., Skarabis H. et al. Evidence for a disease promoting effect of Staphylococcus aureus derived exotoxins in atopic dermatitis. J. Allergy Clin. Immunol., 2000, v. 105 (4), p. 814-819.
- Zollner T.M., Wichelhaus T.A., Hartung A. et al. Colonization with superantigen producing Staphylococcus aureus associated with increased severity of atopic dermatitis. Clin. Exp. Allergy, 2000, v. 30 (7), p. 994-1000.
- Leung D.Y.M., Harbeck R., Bina P. et al. Presence of IgE antibodies to staphylococcal exotoxins on the skin of patients with atopic dermatitis. Evidence for a new group of allergens. J. Clin. Invest., 1993, v. 92, p. 1374-1380.
- Matsui K., Nishikawa A., Suto H. et al. Comparative study of Staphylococcus aureus isolated from lesional and non-lesional skin of atopic dermatitis patients. Microbiol. Immunol., 2000, v. 44 (11), p. 945-947.
- Labrecque N., Thibodeau J., Sekaly R.P. Interaction between staphylococcal superantigens and MHC class II molecules. Semin. Immunol., 1993, v. 5 (1), p. 23-32
- Ройт А., Бростофф Дж., Мейл Д. Иммунология. Пер. с англ., 2000, М., «Мир», 592 с.
- Saloga J., Knop J. Superantigens in skin diseases. Eur. J. Dermatol., 1999, v. 9 (7), p. 586-590.
- Travers J.B., Norris D.A., Leung D.Y.M. The keratinocyte as a target for staphylococcal bacterial toxins. J. Invest. Dermatol., 2001, v. 6 (3), p. 225-230.
- Exepchuk Y.V., Leung D.Y.M., Hiddleton M.H. et al. Staphylococcal toxins and protein A differentially induce cytotoxicity and release of tumor necrosis factor alpha from human keratinocytes. J. Invest. Dermatol., 1996, v. 107, p. 603-609.
- Saloga J., Leung D.Y.M., Reardon C. et al. Cutaneous exposure to the superantigen staphylococcal enterotoxin B elicits a T cell dependent inflammatory response. J. Invest. Dermatol., 1996, v. 106 (5), p. 982-988.
- Davison S., Allen M., Vaughan R., Barker J. Staphylococcal toxin induced T cell proliferation in atopic eczema correlates with increased use of superantigen reactive V-beta in cutaneous lymphocyte-associated antigen (CLA) - positive lymphocytes. Clin. Exp. Immunol., 2000, v. 121(2), p. 181-186.
- Skov L., Baadsgaard O. Superantigens do they have a role in skin diseases? Arch. Dermatol., 1995, v. 131, p. 829-832.
- Wedi B., Wieczorek D., Stunkel T. et al. Staphylococcal exotoxins exert proinflammatory effects through inhibition of eosinofil apoptosis, increased surface antigen expression (CD116, CD45, CD54 and CD69) and enhanced cytokine-activated oxidative burst, thereby trigging allergic, inflammatory reactions. J. of Allergy and Clin. Immunol., 2002, v. 109 (3), p. 477-484.
- Campbell D.E., Kemp A.S. Proliferation and production of interferon gamma and IL4 in response to Staphylococcus aureus and staphylococcal superantigen in childhood atopic dermatitis. Clin. Exp. Immunol., 1997, v. 107 (2), p. 392-397.
- Ou L.S., Goleva E., Hall C., Leung D.Y.M. T regulatory cells in atopic dermatitis and subversion of their activity by superantigens. J. Allergy Clin. Immunol., 2004, v. 113 (4), p. 756-763.
- Bunikowski R., Mielke M.E., Skarabis H. et al. Prevalence and role of serum IgE antibodies to the Staphylo-coccus aureus derived superantigens SEA and SEB in children with atopic dermatitis. J. Allergy Clin. Immunol., 1999, v. 103 (1 Pt. 1), p. 119-124.
- Nissen D., Pedersen L.J., Skov P.S. et al. IgE binding components of Staphylococcal exotoxins in patients with atopic dermatitis. Ann. Allergy Asthma Immunol., 1997, v. 79, p. 403-408.
- Ide F., Matsubara T., Kaneko M. et al. Staphylococcal enterotoxin-specific IgE antibodies in atopic dermatitis. Pediatr. Int., 2004, v. 46 (3), p. 337-341.
- Nomura Y., Tanaka K., Tomita H. et al. Evaluation of staphylococcal exotoxins and their specific IgE in childhood atopic dermatitis. J. Allergy Clin. Immunol., 1999, v. 104 (2Pt1), p. 441-446.
- Hauk D.J., Hamid Q.A., Chrousos G.P., Leung D.Y.M. Induction of corticosteroid insensitivity in human PBMCs by microbial superantigens. J. Allergy Clin. Immunol., 2000, v. 105 (4), p. 782-787.
- Ревякина В.А. Атопический дерматит у детей. Осложненные формы. Лечащий врач, 2003, № 3, с. 53-56.
- Научно-практическая программа «Атопический дерматит и инфекции кожи у детей: диагностика, лечение и профилактика». Руководитель программы Баранов А.А., Москва, 2004, 47 с.
- Смирнова Г.И. Современные подходы к лечению, реабилитации атопического дерматита, осложненного вторичной инфекцией. Аллергология и иммунология в педиатрии, 2004, № 1, с. 34-39.
- Кожные и венерические болезни. Руководство для врачей в 4-х т. Т. 1. Под ред. Ю.К. Скрипкина, 1995, М., Медицина, 576 с.
- Hoeger P.H. Antimicrobial susceptibility of skin-colonizing S. aureus strains in children with atopic dermatitis. Pediatr. Allergy Immunol., 2004, v. 15 (5), p. 474-477.
- Ревякина В.А., Дорохова Н.Ф., Катосова Л.К. и соавт. Некоторые подходы к терапии осложненных форм атопического дерматита у детей. Вестник дерматологии и венерологии, 2000, № 4, с. 38-40.
- Смирнова Г.И. Герпетиформная экзема Капоши при тяжелом течении атопического дерматита у детей. Актуальные вопросы инфекционной патологии у детей. М., 2003 (8-10 декабря), с. 181-182.
- Arkwright P.D., Daniel T.O., Sanyal D. et al. Age-related prevalence and antibiotic resistance of pathogenic staphylococci and streptococci in children with infected atopic dermatitis at a single-specialty center. Arch. Dermatol., 2002, v. 138, p. 939-941.
- Leung D.Y.M. Infection in atopic dermatitis. Curr. Opin. Pediatr., 2003, v. 15 (4), p. 399-404.
- Hanifin J.M., Tofte S.J. Atopic dermatitis - an update for the next millennium. J. Allergy Clin. Immunol., 1999, v. 104 (3), p. 56-78.
- Лечение кожных болезней: Руководство для врачей. Под ред. А.Л. Машкиллейсона, 1990, М., «Медицина», 560 с.
- Пампура А.Н., Чебуркин А.А., Смолкин Ю.С. Современные подходы к терапии атопического дерматита. Леч. врач, 2000, № 4, с. 28-32.
- Lever R. Staphylococcal colonization in atopic dermatitis and the effect of topical mupirocin therapy. Br. J. Dermatol., 1988, v. 119 (2), p. 189-98.
- Stalder J.F., Fleury M., Sourisse M. et al. Local steroid therapy and bacterial skin flora in atopic dermatitis. Br. J. Dermatol., 1994, Oct, v. 131 (4), p. 536-40.
- Faergemann J. A pilot study on the efficacy of mometasone furoate fatty cream on clinical parameters, time to relapse and microbal flora in atopic dermatitis. J. European Acad Dermatol. Venerol., 1997, v. 8,p. 217.
- Adachi J. The effecy of antibiotics on the production of superantigen from Staphylococcus aureus isolated from atopic dermatitis. J. Dermatol. Sci., 2002, v. 28 (1), p. 76-83.
- Nilsson E., Henning C., Hjorleifsson M.L. Density of the microflora in hand eczema before and after topical treatment with a potent corticosteroid. J. Am. Acad. Dermatol., 1986, v. 15 (2Pt 1), p. 192-197.
- Remitz A., Kyllonen H., Granlund H., Reitamo S. Tacrolimus ointment reduces staphylococcal colonization of atopic dermatitis. J. of Allergy and Clin. Immunol., 2001, v. 107 (1), p. 196-19.
- Yoshimura-Mishima M., Akamatsu H., Nomura S., Horio T. Suppressive effect of ultraviolet (UVA and PUVA) radiation on superantigen production by Staphylococcus aureus. J. Dermatol. Sci., 1999, v. 19 (1), p. 31-36.