Features of sensitization to widespread allergens in residents of St. Petersburg and the Leningrad region with common allergic deseases



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Abstract

Background. To identify differences in sensitization to widespread allergens in patients with common allergic diseases: allergic rhinitis, bronchial asthma, angioedema, allergic urticaria and atopic dermatitis. Materials and methods. Determination of sIgE in serum using commercial and domestic reagent kits («AllergoI-FA-specific IgE» and biotinylated allergens of «Alcor Bio», St. Petersburg) was conducted in patients with allergic rhinitis, bronchial asthma, angioedema, allergic urticaria and atopic dermatitis. Results. There was a significant similarity between the spectrum of sensitization in patients with allergic rhinitis and asthma In atopic dermatitis patients the increasing of frequency of food and especially mold sensitization was estimated. The high degree of correlation between the moulds, plants and food allergens in atopic dermatitis was observed. Conclusion. The results obtained in the study can be interesting for physicians in allergological examination and for the researchers to identify new cross-reactive allergens.

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About the authors

O V Aak

North-Western State Medical University named after I.I. Mechnikov

Email: oleg_aak@yahoo.com
Kashkin's Research Institute of Medical Mycology St. Petersburg

A V Sobolev

North-Western State Medical University named after I.I. Mechnikov

Kashkin's Research Institute of Medical Mycology St. Petersburg

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