The prevalence of allergy to fish in children in Tomsk region

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Objective. To investigate the prevalence and clinical manifestations of FA to fish in children in Tomsk region. Patients and methods. In the screening stage the crosssectional study based on screening questionnaires in random samples of children aged 7-10 years (n=13 010) was performed as a part of EuroPrevall project (EuroRrevall, № FP62006TTCTU5 Proposal 045 879). Those, who reported adverse reactions to food in the screening stage were considered as cases (n=652), children without reported reactions were controls (n=636). The casecontrol stage included the completion of a clinical questionnaire, skinprick test to fish (ALK Abellö, Spain), measurement of serum total and specific IgE to fish, componentresolved diagnostics: Cyp c 1, Gad m 1 (ImmunoCAP, ISAC, Phadia, Sweden). Results. The prevalence of verified FA to fish in children 7-10 years in the Tomsk region amounted to 0,32%; in urban children - 0,32%, in rural children - 0,31% (p=0,9). The main manifestations were skin symptoms, oral allergy syndrome, gastrointestinal symptoms. Anaphylactic shock developed in 15% of children with FA to fish. Conclusion. Fish is one of the main triggers of FA in children in Tomsk region, which leads to severe clinical manifestations , including lifethreatening conditions.

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About the authors

O S Fedorova

Siberian State Medical University, Ministry of health of the Russian Federation


L M Ogorodova

Siberian State Medical University, Ministry of health of the Russian Federation

M M Fedotova

Siberian State Medical University, Ministry of health of the Russian Federation

F I Petrovskiy

Yugra Khanty-Mansiysk State Medical Academy

T A Evdokimova

Russian Medical Academy of Postgraduate Education, Ministry of health of the Russian Federation

I I Balasheva

Siberian State Medical University, Ministry of health of the Russian Federation


  1. Boyce J.A., Assa’a A., Burks A.W. et al. NIAID-Sponsored Expert Panel. Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. J. Allergy Clin. Immunol. 2010, v. 126, р. 1-58.
  2. Огородова Л.М., Федорова О.С., Евдокимова Т.А. Молекулярная характеристика пищевых аллергенов животного происхождения. Рос. Аллергол. Журн. 2011, № 5, с. 3-9.
  3. Muraro A., Agache I., Clark A. et al. EAACI food allergy and anaphylaxis guidelines: managing patients with food allergy in the community. Allergy. 2014, v. 69, р. 1046-1057.
  4. Есакова Н.В., Пампура А.Н. Пищевая анафилаксия у детей: триггеры и распространенность. Рос. Аллергол. Журн. 2013, № 4, с. 33-38.
  5. Clark S., Bock S.A., Gaeta T.J. et al. Multicenter Airway Research Collaboration-8 Investigators. Multicenter study of emergency department visits for food allergies. J. Allergy Clin. Immunol. 2004, v. 113, р. 347-352.
  6. Соснина О.Б., Балаболкин И.И., Ботвиньева В.В., Филянская Е.Г. Клинические и иммунные проявления пищевой аллергии у подростков. Рос. педиатр. журнал. 2008, № 3, с. 14-17.
  7. Геппе Н.А., Примак Е.А., Субботина О.А. Пищевая аллергия на рыбу и морепродукты у детей с атопией. Леч. врач. 2010, № 8, с. 48-56.
  8. Федорова О.С., Огородова Л.М., Федотова М.М. и соавт. Распространенность пищевой аллергии у детей в мировом очаге описторхоза: планирование и методология эпидемиологического исследования EuroPrevall. Вестн. РАМН. 2013, № 4, с. 18-25.
  9. Wong G.W.K., Mahesh P.A., Ogorodova L. et al. The EuroPrevall-INCO surveys on the prevalence of food allergies in children from China, India and Russia: the study methodology Allergy. 2009, v. 65, р. 385-390.
  10. Connett G.J., Gerez I., Cabrera-Morales E.A. et al. A population-based study of fish allergy in the Philippines, Singapore and Thailand. Int. Arch. Allergy Immunol. 2012, v. 159, р. 384-390.
  11. Chiang W.C., Kidon M.I., Liew W.K. The changing face of food hypersensitivity in an Asian community. Clin. Exp. Allergy. 2007, v. 37, р. 1055-1061.
  12. Wu T.C., Tsai T.C., Huang C.F. et al. Prevalence of food allergy in Taiwan: a questionnaire-based survey. Intern. Med. J. 2012, v. 42, р. 1310-1315.
  13. Огородова Л.М., Фёдорова О.С., Федотова М.М., Евдокимова Т.А. Формирование пищевой сенсибилизации у детей на фоне инвазии Opisthorchis felineus. Вестн. РАМН. 2014, № 1-2, с. 64-68.
  14. Огородова Л.М., Пузырев В.П., Кобякова О.С. и соавт. Полиморфизм С-703т гена интерлейкина-5 и маркеры эозинофильного воспаления у больных бронхиальной астмой и их родственников. Пульмонология. 2003, № 5, с. 31-34.
  15. Огородова Л., Петровский Ф.И. Выбор оптимальной фармакотерапии астмы. Аллергология. 2005, № 4, с. 3-8.

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