The case of systemic mastocytosis in the practice of the allergist-immunologist

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Mastocytosis is a disease caused by excessive proliferation of mast cells, and it can lead to anaphylactoid reactions. Different mechanisms are involving in the development of anaphylactoid and anaphylactic reactions, however, these reactions have a similar clinical picture. Therefore, patients with mastocytosis can get into the field of view of an allergist-immunologist with suspects insect, food, drug allergy or anaphylaxis of unknown origin. It’s important not only to suggest the correct diagnosis, but also to give the patient the recommendation to reduce the risk of life-threatening reactions. In this article the case of systemic mastocytosis without skin manifestations, which has been regarded for a long time by physicians as drug hypersensitivity is considered.

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About the authors

L G Khludova

Institute of Immunology

T N Myasnikova

Institute of Immunology

Email: t

T S Romanova

Institute of Immunology

T V Latysheva

Institute of Immunology


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