Peculiarities of non-allergic rhinitis with eosinophilia syndrome



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Abstract

Nonallergic rhinitis with eosinophilia syndrome (NARES) is a syndrome containing the symptoms similar to allergic rhinitis, with absence of atopy and the presence of eosinophila more than 20% in smears from nasal mucosa. Pathophysiology of NARES has not been studied completely, but permanent eosinophilic inflammation is the keystone of NARES pathogenesis. This disease is marked by local eosinophilic infiltration without atopy, confirmed by negative skin tests, normal levels of total and specific IgE in serum, negative nasal provocation tests with allergens. Nowadays this nosology is considered to be poorly understood.

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About the authors

V A Utesheva

L.I. Sverzgevsky Moscow Research and Practical Center of Otorhynolaryngology

Email: uteshevalera88@mail.ru

G P Bondareva

Institute of Immunology

A I Kryukov

L.I. Sverzgevsky Moscow Research and Practical Center of Otorhynolaryngology

T G Barkhina

Institute of Human Morphology

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