Prospects for studying of FOXP3 and its isoforms expression in allergic diseases



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Abstract

In this review we describe FOXP3 (a specific marker of regulatory T-cells), nature of FOXP3 isoforms (with or without exon 2) expression and cooperation with other transcription factors under various immunopathological conditions and discuss the prospects for studying of FOXP3 isoforms expression in CD4+ T-cells in allergic diseases.

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About the authors

D S Smirnov

Institute of Immunology

Email: freeeezy@mail.ru

O M Kurbacheva

Institute of Immunology

S A Polner

Institute of Immunology

K S Pavlova

Institute of Immunology

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