Drug-induced anaphylaxis: prevalence, risk factors, triggers

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Abstract


Currently, there is a tendency to increase the prevalence of drug-induced anaphylaxis. Medicines occupy a leading position among the causes of the development of anaphylactic reactions in the adult group of patients and second place in children, the most significant in this matter are non-steroidal anti-inflammatory drugs, antibacterial drugs and X-ray contrast agents. The risk of developing of drug anaphylaxis in most cases is not predictable, while the frequency of severe and fatal reactions is extremely high. This article presents an analysis of current data regarding the prevalence, possible risk factors, and triggers of drug anaphylaxis.

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Natalia V Esakova

Academician Yu.E. Veltishchev Research Clinical Institute of Pediatrics N.I. Pirogov Russian National Research Medical University

Email: env007@rambler.ru

Alexander Nikolaevich Pampura

Academician Yu.E. Veltishchev Research Clinical Institute of Pediatrics N.I. Pirogov Russian National Research Medical University

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