Features of asthma treatment during pregnancy

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Study goal. To analyse asthma therapy in pregnant women with bronchial asthma at a period since 2002 to 2017. Materials and methods. 3890 pregnant women with asthma were examined and followed up during pregnancy at a period since 2002 to 2017. Comprehensive clinicalfunctional examination was conducted. Patients were under surveillance of the obstetriciangynecologist during the whole pregnancy, standard procedures were carried out, and the frequency of complications of pregnancy was estimated. Basic therapy of asthma was compared in groups with the persistent asthma duration, followed up since 2002 to 2009 (1 group) and since 2010 to 2017 (2 group). Also, frequency of pregnancy complications was estimated in these groups. Results. The second group (2010-2017) demonstrated reliably lower frequency of threatening abortion, hypertension and preeclampsia. At the same time the frequency of inhaled corticosteroids (ICS) administration as a part of the combined therapy increased from 21.79% to 63.87% (almost to three times) in comparison with the first group (2002-2009). Conclusions. Combined therapy with ICS/LABA provides most complete control of bronchial asthma, and decreases frequency of pregnancy complications in pregnant women with BA.

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About the authors

O V Lavrova

Pavlov First State Medical University

Email: loverova@bk.ru

M A Petrova

Pavlov First State Medical University

G B \\Fedoseev

Pavlov First State Medical University


  1. Лаврова ОВ, Петрова МА. Первые результаты анализа распространенности аллергических заболеваний у женщин детородного возраста в г. Санкт-Петербурге. Медицинский альянс. 2017;(4):88-92
  2. Charlton RA, Hutchison A., Davis KJ. Asthma Management in Pregnancy. PLoS One. 2013;8:e60247. doi: 10.1371/journal. pone.0060247.
  3. Rejno G., Lundholm C., Gong T., Larsson K., Saltvedt S., Almqvist C. Asthma during pregnancy in a population-based study - pregnancy complications and adverse perinatal outcomes. PLoS One. 2014;9:e104755. doi: 10.1371/journal. pone.0104755.
  4. Christensson C., Thoren A., Lindberg B. Safety of inhaled budesonide: clinical manifestations of systemic corticosteroid-related adverse effects. Drug Saf. 2008;31:965-988. doi: 10.2165/00002018-200831110-00002.
  5. Cossette B., Beauchesne MF, Forget A., Lemiere C., Larivee P., Rey E., Blais L. Relative perinatal safety of salmeterol vs formo-terol and fluticasone vs budesonide use during pregnancy. Ann Allergy Asthma Immunol. 2014;112:459-464. DOI: 10.1016/j. anai.2014.02.010.



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