Respirator naya virusnaya infektsiyai bro nkhoo bstruktivnye zabolevaniya



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Abstract

Обобщены данные о роли респираторной вирусной инфекции в формировании бронхиальной астмы,
провоцировании обострений, а также участие различных респираторных вирусов в патогенезе бронхо-
обструктивных заболеваний.

About the authors

M R Khaitov

S V Tsarev

References

  1. Kuypers J. Clinical Disease in Children Associated With Newly Described Coronavirus Subtypes. Pediatrics. 2007, v. 119, p. 70-76.
  2. Busse W.W. The role of respiratory viruses in asthma. In:
  3. Holgate S., ed. Asthma: physiology, immunopharmacology, and treatment. London: Academic Press. 1993, p. 345-352.Gern J.E., Lemanske R.F. Infectious triggers of pediatric asthma. Pediatr. Clin. North Am. 2003, v. 50 (3), p. 555-575.
  4. Johnston, S.L., Pattemore P.K, Sanderson G. et al. Community study of role of viral infections in exacerbations of asthma in 9-11 year old children. Br. Med. J. 1995, v. 310, p. 1225-1229.
  5. Nicholson, K.G., Kent J., Ireland D.C. Respiratory viruses and exacerbations of asthma in adults. Br. Med. J. 1993, v. 307, p. 982-986.
  6. Johnston, S.L., Pattemore P.K, Sanderson G. et al. The relationship between upper respiratory infections and hospital admissions for asthma: a time trend analysis. Am. J. Respir. Crit. Care Med. 1996, v. 154, p. 654-660.
  7. Campbell M.J., Holgate S.T., Johnston S. L. Trends in asthma mortality. Br. Med. J. 1997, v. 315, p. 1012.
  8. Shirakawa T., Enomot T., Shimazu S-I, Hopkin J.M. The inverse association between tuberculin responses and atopic disorder. Science. 1997, р. 275-277.
  9. Wark P.A., Johnston S. L., Moric I. Neutrophil degranulation and cell lysis is associated with clinical severity in virus-induced asthma. Evr. Respir. J. 2002, v. 19, p. 68-75.
  10. Duff A.L., Pomeranz E.S., Gelber L.E. et al. Risk factors for acute wheezing in infants and children: viruses, passive smoke, and IgE antibodies to inhalant allergens. Pediatrics. 1993, v. 92, p. 535-540.
  11. Proud D., Chow C.-W. Role of Viral Infections in Asthma and Chronic Obstructive Pulmonary Disease. American Journal of Respiratory Cell and Molecular Biology. 2006, v. 35, p. 513-518.
  12. Mallia P., Contoli M., Caramori G. et al. Exacerbations of asthma and chronic obstructive pulmonary disease (COPD): focus on virus induced exacerbations. Curr. Pharm. Des. 2007, v. 13 (1), p. 73-97.
  13. Traves S.L., Proud D. Viral-associated exacerbations of asthma and COPD. Curr Opin Pharmacol. 2007, v. 7 (3), p. 252-258.
  14. Johnston S.L. Overview of virus-induced airway disease. Proc.
  15. Am. Thorac Soc. 2005, v. 2 (2), p.150-156.
  16. Wedzicha J.A. Role of viruses in exacerbations of chronic obstructive pulmonary disease. Proc. Am. Thorac. Soc. 2004, v. 1 (2), p. 115-120
  17. Frick O.L., German D.F., Mills J. Development of allergy in children. I. Association with virus infections. J. Allergy Clin. Immunol. 1979, v. 63, p. 228-241.
  18. Балаболкин И.И. Бронхиальная астма у детей. М., «Медицина ». 2003, 320 с.
  19. Булгакова В.А., Балаболкин И.И., Сенцова Т.Б. Респираторная вирусная инфекция у детей и подростков с аллергической патологией. Детские инфекции. 2005, № 4, с. 17-24. 19. Jartti T, Lehtinen P, Vuorinen T. et al. Respiratory picornaviruses and respiratory syncytial virus as causative agents of acute expiratory wheezing in children. Emerg. Infect. Dis. 2004, v. 10, p. 1095-1101.
  20. Azevedo A.M., Durigon E.L., Okasima V. et al. Detection of influenza, parainfluenza, adenovirus and respiratory syncytial virus during asthma attacks in children older than 2 years old. Allergol Immunopathol (Madr). 2003, v. 31, p. 311-317.
  21. Mosser A.B, Vrtis R., Burchell L. et al. Quantitative and qualitative analysis of rhinovirus infection in bronchial tisues.Am. J. Respir. Crit. Care Med. 2005, 171, p. 645-651.
  22. Grissell T.V., Powell H., Shafren D.R. et al. Interleukin-10 Gene Expression in Acute Virus-induced Asthma. American Journal of Respiratory and Critical Care Medicine. 2005, v. 172. p. 433-439.
  23. Martinez F.D, Wright A.L, Taussig L.M. et al. Asthma and wheezing in the first six years of life. N. EngI. J. Med. 1995, v. 332 (3), p. 133-138.
  24. Stein R.T., Sherrill D., Morgan W.J. et al. Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years. Lancet. 1999, v. 354, p. 541-545.
  25. Johnston S.L. Viruses and asthma. Allergy. 1998, v. 53 (10), p. 922-932.
  26. Wu C.A., Puddington L., Whiteley H.E. et al. Cytome-galovirus Infection Alters Th1/Th2 Cytokine Expression, Decreases Airway Eosinophilia, and Enhances Mucus Production in Allergic Airway Disease. J. Immunol. 2001, v. 167 (5), p. 2798-2807.
  27. Ohnishi E., Iwata T., Inouye S. Interleukin-4 production in Epstein-Barr virus-transformed B cell lines from peripheral mononuclear cells of patient with atopic dermatitis. J. Interferon Cytokine Res. 1997, v. 17, p. 597-602.
  28. Sidorchuk A., Lagarde F., Pershagen G. Epstein-Barr virus infection is not associated with development of allergy in children. Pediatr. Infect. Dis. J. 2003, v. 22, p. 642-647.
  29. Харламова Ф.С., Легкова Т.П., Фельдфикс Л.И. и cоавт. Клинико-патогенетическое обоснование иммунокорригирующей и противовирусной терапии при персистирующей герпетической инфекции у детей с рецидивирующим крупом и обструктивным бронхитом. Детские инфекции. 2005, № 4, с. 10-17.
  30. Sigurs N., Bjarnason R., Sigurbergsson F., Kjellman B. Respiratory syncytial virus bronchiolitis in infancy is al important risk factor for asthma and allergy at the 7. Am. J. Respir. Crit. Care Med. 2000, 161, p. 1501-1507.
  31. Sigurs N. Epidemiologic and clinical evidence of a respiratory syncytial virus-reactive airway disease link. Am. J. Respir. Crit. Care Med., 2001, v. 163 (3), p. S2-S6.
  32. Ahmed R., Morrison L.A., Knipe D.M. Persistence of viruses. In Fields virology. B.N. Fields, D.M. Knipe, P.M. Howley, editors. Lippincott Williams & Wilkins. Philadelphia, Pennsylvania, USA. 1996, p. 219-249.
  33. Murray M., Webb M.S., O'Callaghan C. et al. Respirator status and allergy after bronchiolitis. Arch. Dis. Child. 1992, 67, p. 482-487.
  34. Pullan CR., Hey E.N. Wheezing, asthma, and pulmonary dysfunction 10 years after infection with respiratory syncytial virus in infancy. Br. Med. J. 1982, v. 284, p. 1665-1669.
  35. Sterk P. J. Virus-induced airway hyperresponsiveness in man. Eur. Respir. J. 1993. v. 6. p. 894-902.
  36. Martinez F.D., Morgan W.J., Wright A.L. et al. Diminished lung function as a predisposing factor for wheezing respiratory illness in infants. N. Engl. J. Med. 1988, v. 319, p. 1112-1117.
  37. Greenberg S.B. Respiratory viral infection in high-risk patients. Am. J. Respir. Crit. Care Med. 2004, v. 170, p. 1142-1143.
  38. Papi A., Luppi F., Franco F., Fabbri L.M. Pathophysiology of exacerbations of chronic obstructive pulmonary disease. Proc. Am. Thorac. Soc. 2006, v. 3, p. 245-251.
  39. Селькова Е.П. Современные подходы к профилактике и лечению острых респираторных вирусных инфекций. Рус. мед. журн. 2001, № 9, c. 960-962.
  40. Wilkinson T.M.A., Donaldson G.C., Johnston S.L. еt al. Respiratory syncytial virus, airway inflammation, and FEV1 decline in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 2006, v. 173, p. 871-876.
  41. Собченко С.А., Счетчикова О.С., Яковлева Н.В. Обострение неаллергической поздней астмы, индуцированное респираторной инфекцией. Пульмонология. 2005, № 1, с. 53-57.
  42. Shaheen, S.O. Changing patterns of childhood infection and the rise in allergic disease. Clin. Exp. Allergy. 1995, v. 25, p. 1034-1037.
  43. Shaheen, S.O., Aaby P., Hall A.J. et al. Measles and atopy in Guinea-Bissau. Lancet. 1996, v. 347, p. 1792-1796.
  44. Johnston S.L, Bardin P.G, Pattemore P.K. Viruses as precipitants of asthma symptoms. III. Rhinoviruses: Molecular biology and prospects for future intervention. Clin. Exp. Allergy. 1993, v. 23 (4), p. 237-246.
  45. von Mutius E., Martinez F.D, Fritzsch C. et al. Skin test reactivity and number of siblings. Br. Med. J. 1994, v. 308, p. 692-695.
  46. Strachan D.P., Harkins L.S., Johnston I.D.A., AndersonH.R. Childhood antecedents of allergic sensitization in young British adults. J Allergy Clin Immunol. 1997, v. 99, p. 6-12.
  47. Imani F., Proud.D., Griffin D.E. Measles virus infection synergizes with IL-4 in IgE class switching. J. Immunol. 1999, v. 162, p. 1597-1602.
  48. Alm, J.S., Lilja G., Pershagen G., Scheynius A. Early BCG vaccination and development of atopy. Lancet. 1997, v. 350, p. 400-403.
  49. Folkerts G., Busse W.W., Nijkamp F.P. et al. Virus-induced Airway Hyperresponsiveness and Asthma. Am. J. Respir. Crit. Care Med. 1998, V. 157 (6), p. 1708-1720.
  50. Femandez-Benitez M. The role of infection in asthma. J. Allergologia et immunologia. 2001, v. 29 (3), p. 147-151.
  51. Хаитов М.Р. Острые респираторные вирусные инфекции и бронхиальная астма. Клеточные и молекулярные аспекты проблемы. ЖМЭИ. 2002, № 4, с. 84-93.
  52. Dakhama A., Lee Y.M., Gelfand E. W Virus-induced airway dysfunction: pathogenesis and biomechanisms. Pediatr. Infect. Dis. 2005, v. 24 (suppl. II), p. S159-S169; discus.: S166-S167.
  53. Piedimonte G. Contribution of neuroimmune mechanisms to airway inflammation and remodeling during and after respiratory syncytial virus infection. Pediatr. Infect. Dis. 2003, v. 22 (suppl. 2), p. 66-74.
  54. Gern J.Е, Calhoun W.J., Swenson С. et al. Rhinovirus infection preferentially increases lower airway responsiveness in allergic subjects. Ibid. 1997, v. 155, p. 1872-1876.
  55. Empey D.W., Laitinen L.A., Jacobs L. et al. Mechanisms of bronchial hyperreactivity in normal subjects after upper respiratory tract infection. Am. Rev. Respir. Dis. 1976, v. 113, p. 131-139.
  56. Bardin P. G., Sanderson G., Robinson B. S. et al. Experimental rhinovirus infection in volunteers. Eur. Respir. J. 1996, v. 9, p. 2250-2255.
  57. Fraenkel, D.J., Bardin P.G., Sanderson G. et al. Lower airway inflammation during rhinovirus colds in normal and in asthmatic subjects. Am. J. Respir. Crit. Care Med. 1995, v. 151, p. 879-886.
  58. Lemanske R.F. Jr., Dick E.C., Swenson C.A. et al. Rhinovirus upper respiratory infection increases airway hyperreactivity and late asthmatic reactions. J. Clin. Invest. 1989, v. 83, p. 1-10.
  59. Angelini B., Van Deusen B.S, Doyle W.J. et al. Lower airway responses to rhinovirus in healthy subjects with and without allergy. J. Allergy Clin. Immunol. 1997, v. 99, p. 618-619.
  60. Skoner D.P., Doyle W. J., Seroky J., Fireman P. Lower airway responses to influenza A virus in healthy allergic and nonallergic subjects. Am. J. Respir. Crit. Care Med. 1996, v. 154, p. 661-664.
  61. Shwarze J., Hamelmann Е., Bradley К L. et al. Respiratory syncitial virus results in airway hyperresponsiveness and еnhanсеd airway sensitization to allergen. J. Clin. Invest. 1997, v. 100, p. 226-233.
  62. Henrickson K.J. Parainfluenza Viruses. Clin. Microbiol. Rev. 2003, v. 16, p. 242-64.
  63. Walter M. J., Morton J. D, Kajiwara N. et al. Viral induction of a chronic asthma phenotype and genetic segregation from the acute response. J. Clin. Invest. 2002, v. 110, p. 165-75.
  64. Peebles R.S., Sheller J.R., Johnson J.E. et al. Respiratory syncytial virus infection prolongs methacholine-induced airway hyperresponsiveness in ovalbumin sensitized mice. J. Med. Virol. 1999, v. 57, p. 186-192.
  65. Cheung D., Dick E. C., Timmers M.C. et al. Rhinovirus inhalation causes long-lasting excessive airway narrowing in response to methacholine in asthmatic subjects in vivo. Am. J. Respir. Crit. Care Med. 1995, v. 152, p. 1490-1496.
  66. Halperin, S.A., Eggleston P.A., Beasley P., et al. Exacerbations of asthma in adults during experimental rhinovirus infection. Am. Rev. Respir. Dis. 1985, v. 132, p. 976-98
  67. Пыцкий В.И. Некоторые дискуссионные проблемы аллергологии. ІІ. Взгляд на бронхиальную астму и атопию. Часть І. Рос. аллергол. журн. 2006, № 6, с. 42-58.
  68. Weiss S.T., Tager I.B., Munoz A., Speizer F.E. The relationship of respiratory infections in early childhood to the occurrence of increased levels of bronchial responsiveness and atopy. Am. Rev. Respir. Dis. 1985, v. 131 (4), p. 573-578.
  69. Schwarze J., Gelfand E.W. Respiratory virus infections as promoters of allergic sensitization and asthma in animal models. Eur. Respir. J. 2002, v. 19, p. 341-349.
  70. Гущин И.С. Аллергенная проницаемость барьерных тканей - стратегическая проблема аллергологии. Пульмонология. 2006, № 3, с. 5-13.
  71. Johnston S.L. Mechanisms of asthma exacerbation. Clin. Exp. Allergy. 1998, v. 28 (s5), p. 181-186.
  72. Martinez F.D. Viruses and atopic sensitization in the first years of life. Am. J. Respir. Crit Care Med. 2000, v. 162, p. 395-399.
  73. Ltibovitz E., Freihorst J., Piedra P.A., Ogra P.L. Modulation of systemic and mucosal immune responses to inhaled ragweed antigen in experimentally induced infection with respiratory syncytial virus implication in virally induced allergy. Int. Arch. Allergy Appl. Immunol. 1988, v. 86, p. 112-116.
  74. Freihorst J., Piedra P.A., Okamoto Y., Ogra PL Effect of respiratory syncytial virus infection on the uptake of immune response to other inhaled antigens. Proc. Soc. Exp. BioI. (N. Y). 1988, v. 188, p. 191-197.
  75. Riedel F., Krause A., Slenczka W., Rieger C.H. Parainfluenza-3-virus infection enhances allergic sensitization in the guinea-pig. Clin. Exp. Allergy. 1996, v. 26, p. 603-609.
  76. Dakhama A., Bramley A.M., Chan NG. et al. Effect of respiratory syncytial virus on subsequent allergic sensitization to ovalbumin in guinea-pigs. Eur. Respir. J. 1999, v 13, p. 976-982.
  77. Tsitoura D.C, Kim S., Dabbagh K. et al. Respiratory infection with influenza A virus interferes with the induction of tolerance to aeroallergens. J. Immunol. 2000, v. 165, p. 3484-3491.
  78. Yamamoto N., Suzuki S., Shirai A. et al. Dendritic cells are associated with augmentation of antigen sensitization by influenza A virus infection in mice. Eur. J. Immunol. 2000, v. 5, p. 316-326.
  79. Piedimonte G., Hoffman J.I.E., Husseini W.K. et al. NK1 receptors mediate neurogenic inflammatory increase in blood flow in rat airways. J. Appl. Physiol. 1993, v. 74, p. 2462-2468.
  80. Gern J.E, Galagan D.M., Janour N.N. et al. Detection of rhinovirus RNA in lower airway cells during experimentally-induced i n f e c t i o n . Am. J . R e s p i r. C n t . C a r e Me d . 1 9 9 7 , v. 155, p. 1159-1161.
  81. Proud D., Chow C.-W. Role of Viral Infections in Asthma and Chronic Obstructive Pulmonary Disease. American Journal of Respiratory Cell and Molecular Biology. 2006, v. 35, p. 513-518.
  82. Calhoun W.J., Dick E.C., Schwartz L.B., Busse W.W. A common cold virus, rhinovirus 16 potentiates airway inflammation after segmental antigen bronchoprovocation in allergic subjects. J. Clin. Invest. 1994, v. 94, p. 2200-2208.
  83. Skoner D.P., Doyle W.J., Tannery E.P. et al. Effect of rhinovirus 39 (RV-19) infection on immune and inflammatory parameters in allergic and non-allergic subjects. Clin. Exp. Allergy. 1995, v. 25, p. 561-563.
  84. Seminario M.C., Squillace D., Bardin P.G. et al. Increased levels of eosinophil major basic protein in nasal secretions in rhinovirus infection. J. Allergy Clin. Immunol. 1995, v. 95, p. 259-264.
  85. Volvovitz В., Welliver R.C., De Castro G. et al. The release of leukotrienes in the respiratory tract during infection with respiratory syncytial virus: Role in obstructive airway disease. Pediatr Res. 1988, v. 24, p. 504-506.
  86. Jarjour N.N., Gern J.E., Kelly E.A., Swenson C.A., Dick C.R., Busse W.W. The effect of an experimental rhinovirus 16 infection on bronchial lavage neutrophils. J. Allergy Clin. Immunol. 2000, v. 105, p. 1169-1177.
  87. Wark P.A., Johnston S.L., Moric I. et al. Neutrophil degranulation and cell lysis is associated with clinical severity in virus-induced asthma. Eur Respir. J. 2002, v. 19, p. 68-75.
  88. Norzila M.Z., Fakes K., Henry R.L. et al. Interleukin-8 secretion and neutrophil recruitment accompanies induced sputum eosinophil activation in children with acute asthma. Am. J. Respir. Crit. Care Med. 2000, v. 161, p. 769-774.
  89. Proud D., Gwaltney J.M., Hendley J.O. et al. Increased levels of interleukin-1 are detected in nasal secretions of volunteers during experimental rhinovirus colds. J. Infect. Dis. 1994, v. 169, p. 1007-1009.
  90. Linden M., Greiff L., Andersson M. et al. Nasal cytokines in common cold and allergic rhmitis. Clin. Exp. Allergy. 1995, v. 25, p.166-169.
  91. Grunberg K., Timmer M.C., Smits H.H. et al. Effect of experimental rhinovirus 16 colds on airway hyperrespon-siveness to histamine and interleukin-8 in nasal lavage in asthmatic subjects in vivo. Clin. Exp. Allergy. 1997, v. 27, p. 36-45.
  92. Einarsson, O., Geba G. P., Zhu Z. et al. Interleukin-11: stimulation in vivo and in vitro by respiratory viruses and induction of airways hyperresponsiveness. J. Clin. Invest. 1996, v. 97, p. 915-924.
  93. Caramori G., Ito K., Contoly M., Di Stefano A. et al. Molecular mechanisms of respiratory virus-induced asthma and COPD exacerbations and pneumonia. Curr. Med. Chem. 2006, v. 13 (19), p. 2267-2290.
  94. Teran L.M., Seminario M.C., Shute J.K. et al. RANTES, macrophage-inhibitory protein 1α, and the eosinophil product major basic protein are released into upper respiratory secretions during virus-induced asthma exacerbations in children. J. Infect. Dis. 1999, v.179, p.677-681.
  95. Oh JW, Lee HB, Park IK, Kang JO. Interleukin-6, interleukin -8, interleukin-11, and interferon-γ levels in nasopharyngeal aspirates from wheezing children with respiratory syncytial virus or influenza A virus infection. Pediatr. Allergy Immunol. 2002, v. 13, p. 350-356.
  96. Zhu, Z., Tang W., Wu Y. et al. Rhinovirus stimulation of interleukin-6 in vivo and in vitro: evidence for nuclear factor kappa B-dependent transcriptional activation. J. Clin. Invest. 1996, v. 97, p. 421-430.
  97. Barnes, P.J., I.M. Adcock. NF-kappa B: a pivotal role in asthma and a new target for therapy. Trends. Pharmacol. Sci. 1997, v. 18, p. 46-50.
  98. Thomas K.W., Monick M.M., J.M. Staber. et al. Respiratory syncytial virus inhibits apoptosis and induces NF-kappa B activity through a phosphatidylinositol 3-kinase-dependent pathway. J. Biol. Chem. 2002, v. 277 (1), p. 492-501.
  99. Oumouna M., Mapletoft J.W., Karvonen B.C. et al. Formulation with CpG oligodeoxynucleotides prevents induction of pulmonary immunopathology following priming with formalin-inactivated or commercial killed bovine respiratory syncytial virus vaccine. J. Virol. 2005, v. 79, p. 2024-2032.
  100. Gern J.E., Busse W.W. Role of Т. cells in virus-induced asthma. In: Liggett S.B., Meyers D.A. (Eds). The Genetics of Asthma, Marcel Dekker, New York. 1996, p. 39-66.
  101. Roman M., Calhoun W.J., Hinton K.L. et al. Respiratory syncytial virus infection in infants is associated with predominant Th2-like response. Am. J. Respir. Crit. Care Med. 1997, v. 156, p. 190-195.
  102. Menzies-Gow A., Robinson D.S. Eosinophils, eosinophilic cytokines (interleukin-5), and antieosinophilic therapy in asthma. Curr. Opin. Pulm. Med. 2002, v. 8, p. 33-38.
  103. Koga, T., Sardina E., Tidwell R.M. et al. Virus-inducible expression of a host chemokine gene relies on replication-linked mRNA stabilization. Proc. Natl. Acad. Sci. USA. 1999,v. 96, p. 5680-5685.
  104. Sampath D., Castro M., Look D.C., Holtzman M.J. Constitutive activation of an epithelial signal transducer and activator of transcription (Stat1) pathway in asthma. J. Clin. Invest. 1999. v. 103, p. 1353-1361.
  105. Walter M.J., Kajiwara N., Karanja P. et al.. IL-12 p 40 production by barrier epithelial cells during airway inflammation. J. Exp. Med. 2001. v. 193, p. 339-352.
  106. Walter M. J., Morton J. D., Kajiwara N. et al. Viral induction of a chronic asthma phenotype and genetic segregation from the acute response. J. Clin. Invest. 2002, v. 110, p. 165-175.
  107. Rager K.J., Langland J.O., Jacobs B.L. et al. Activation of antiviral protein kinase leads to immunoglobulin E class switching in human B cells. J. Virol. 1998, v. 72, p. 1171-1176.
  108. Welliver R.C., Kaul T.N., Ogra P.L. The appearance of cell-bound IgE in respiratory-tract epiffielium after respiratory-syncytial-virus infection. N. Engl. J. Med. 1980, v. 303, p. 1198.
  109. O'Donnel D.R., Openshaw Р.J.М. Anaphylactic sensitization to аеroаntigеn during respiratory virus infection. Clin. Ехр. Allergy. 1998, v. 57, p. 214-219.
  110. Dakhama A., Park J.-W., Taube C. et al. The Role of Virus-specific Immunoglobulin E in Airway Hyperresponsiveness. American Journal of Respiratory and Critical Care Medicine. 2004, v. 170, p. 952-959.
  111. Wood L.G. Persistent Airway Obstruction After Virus Infection Is Not Associated With Airway Inflammation. Chest. 2007, v. 131, p. 415-423.
  112. Graham B.S., Johnson T.R., Peebles R.S. Immune-mediated disease pathogenesis in respiratory syncytial virus infection. Immunopharmacology. 2000, v. 48, p. 237-247.
  113. Makela M.J., Tripp R., Dakhama A. et al. Prior airway exposure to allergen increases virus-induced airway hyperresponsiveness.J. Allergy Clin. Immunol. 2003, v. 112, p. 861-870.
  114. Ordonez C., Khashayar R., Wong H.H. et al. Mild and moderate asthma is associated with airway goblet cell hyperplasia and abnormalities in mucin gene expression. Am. J. Respir. Crit. Care Med. 2001, v. 163, p. 517-523.
  115. Chen Y., Thai P., Zhao Y.H. et al. Stimulation of airway mucin gene expression by interleukin 17 though IL-6 paracrine/autocrineloop. J. Biol Chem. 2003, v. 278, p. 17036-17043.
  116. Hoshino M., Morita S., Iwashita S. et al. Increased expression of the human Ca2+-activated Cl- channel 1 (CaCC1) gene in the asthmatic airway. Am. J. Respir. Crit. Care Med. 2002, v. 165, p. 1132-1136.
  117. Hashimoto K., Graham B.S., Ho S.B. et al. Respiratory syncytial virus in allergic lung inflammation increases Muc5ac and gob-5. Am. J. Respir. Crit. Care Med. 2004, v. 170 p. 306-312.
  118. Holtzman M.J., Tyner J.W., Kim E.Y. et al. Acute and chronic airway responses to viral infection: implications for asthma and chronic obstructive pulmonary disease. Proc. Am. Thorac Soc. 2005, v. 2 (2), p. 132-40.
  119. Sorkness R., J. J. Clough, W. L. Castleman, R. F. Lemanske. Virus-induced airway obstruction and parasympathetic hyperresponsiveness in adult rats. Am. J. Respir. Crit. Care Med. 1994, v. 150, p. 28-34.
  120. Fryer A.D., Jacoby D.B. Parainfluenza virus infection damages inhibitory M2 muscarinic receptors on pulmonary parasympathetic nerves in the guinea pig. Br. J. Pharmacol. 1991, v. 102, p. 267-271.
  121. Colasurdo, G.N., V.G. Hemming, G.A. Prince et al. Human respiratory syncytial virus affects nonadrenergic noncholinergic inhibition in cotton rat airways. Am. J. Physiol. (Lung Cell Mol. Physiol.) 1995, v. 12, p. L1006-L1011.
  122. Folkerts, G., H.J. van der Linde, F.P. Nijkamp. Virus- induced airway hyperresponsiveness in guinea pigs is related to a deficiency in nitric oxide. J. Clin. Invest., 1995, v. 95, p. 26-30.

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