Allergic bronchopulmonar aspergillosis in asthmatic patients



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Abstract

Allergic bronchopulmonary aspergillosis (ABPA) is a caused by hypersensitivity to Aspergillus spp. antigens, is the lung disease, which occurs in patients with asthma or cystic fibrosis and is characterized by poor control of background disease and development of respiratory failure. According to experts opinion the number of patients with ABPA is about four million people in the world and 175 000 persons in Russian Federation. The clinical course improvement, prevention of progression and prophylaxis of bronchiectasis depend on timely and correct diagnosis of the disease. International Society of Human and Animal Mycology (ISHAM) formed a working group «ABPA in patients with asthma» for worldwide collaboration with physicians and researchers. The working group proposed new diagnostic criteria. This report presents a clinical case of ABPA in asthmatic patient. The diagnosis is established according criteria proposed by R. Agarwal et al., 2013.

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About the authors

Y I Kozlova

North-Western State Medical University named after I.I. Mechnikov

Email: kozlova510@mail.ru

A V Sobolev

North-Western State Medical University named after I.I. Mechnikov

E V Frolova

North-Western State Medical University named after I.I. Mechnikov

O V Aak

North-Western State Medical University named after I.I. Mechnikov

E V Burygina

North-Western State Medical University named after I.I. Mechnikov

N N Klimko

North-Western State Medical University named after I.I. Mechnikov

References

  1. Agarwal R. Allergic bronchopulmonary aspergillosis. Chest. 2009, v. 135, р. 805-826.
  2. Hogan C., Denning D.W. Allergic bronchopulmonary aspergillosis and related allergic syndromes. Semin. Respir. Crit. Care Med. 2011, v. 32, р. 682-692.
  3. Agarwal R., Chakrabarti A., Shah A. et al. For the ABPA complicating asthma ISHAM working group Allergic bronchopulmonary aspergillosis: review of literature and proposal of new diagnostic and classification criteria. Clinical & Experimental Allergy. 2013, v. 43, р. 850-873.
  4. ABPA complicating asthma working group. http://www.abpaworkinggroup.org.
  5. Agarwal R., Chakrabarti A. Epidemiology ofallergic bronchopulmonary aspergillosis. In: Pasqualotto A.C. Aspergillosis: from diagnosis to prevention. New York, Springer. 2010, р. 671-688.
  6. Agarwal R., Aggarwal A.N., Gupta D., Jindal S.K. Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with bronchial asthma: systematic review and metaanalysis. Int. J. Tuberc. Lung. Dis. 2009, v. 13, р. 936-944.
  7. Fairs A., Agbetile J., Hargadon B. et al. IgE sensitization to Aspergillus fumigatus is associated with reduced lung function in asthma. Am. J. Respir. Crit. Care Med. 2010, v. 182, р. 1362-1368.
  8. Menzies D., Holmes L., McCumesky G. et al. Aspergillus sensitization is associated with airflow limitation and bronchiectasis in severe asthma. Allergy. 2011, v. 66, р. 679-685.
  9. Agarwal R., Noel V., Aggarwal A.N. et al. Clinical significance of Aspergillus sensitization in bronchial asthma. Mycoses. 2011, v. 54, р. 531-538.
  10. Agbetile J., Fairs A., Desai D. et al. Isolation of filamentous fungi from sputum in asthma is associated with reduced post-bronchodilator FEV(1). Clin. Exp. Allergy. 2012, v. 42, р. 782-791.
  11. Chowdhary A., Agarwal K., Kathuria S. et al. Allergic bronchopulmonary mycosis due to fungi other than Aspergillus: a global overview. Crit. Rev. Microbiol. 2013, doi: 10.3109/1040841X.2012.75 4401.
  12. Denning D.W., O’Driscoll B.R., Hogaboam C.M. et al. The link between fungi and severe asthma: a summary of the evidence. Eur. Respir. J. 2006, v. 27, р. 615-626.
  13. Denning D.W., O’Driscoll B.R., Powell G. et al. Randomized controlled trial of oral antifungal treatment for severe asthma with fungal sensitization: the Fungal Asthma Sensitization Trial (FAST) study. Respir. Crit. Care Med. 2009, v. 179, р. 11-18.
  14. Gergen P.J., Arbes S.J., Calatroni A. et al. Total IgE levels and asthma prevalence in the US population: results from the National Health and Nutrition Examination Survey 2005-2006. Allergy Clin. Immunol. 2009, v. 124, р. 447-453.
  15. Denning D.W., Pleuvry A., Cole D.C. Global burden of allergic bronchopulmonary aspergillosis with asthma and its complication chronic pulmonary aspergillosis in adults. Med. Mycol. 2013, v. 51, р. 361-370.
  16. Agorwal R., Denning D.W., Chakrabarti A. Estimation of the Burden of Chronic and Allergic Pulmonary Aspergillosis in India. PLoS One. 2014, v. 5, р. 1-10.
  17. Климко Н.Н., Козлова Я.И., Хостелиди С.Н. и соавт. Распространенность тяжелых и хронических микотических заболеваний в Российской Федерации по модели LIFE program. Проблемы медицинской микологии. 2014, № 1, с. 3-9.
  18. Moss R.B. Allergic bronchopulmonary aspergillosis and Aspergillus infection in cystic fibrosis. Curr. Opin. Pulm. Med. 2010, v. 16, p. 598-603.
  19. Kraemer R., Delosea N., Ballinari P. et al. Effect of allergic bronchopulmonary aspergillosis on lung function in children with cystic fibrosis. Respir. Crit. Care Med. 2006, v. 174, p. 1211-1220.
  20. Moss R.B. Practicalities of ABPA diagnosis and treatment. Pediatr. Pulmonol. 2009, v. 44, p. 201-202.
  21. Stevens D.A., Moss R.B., Kurup V.P. et al. Participants in the Cystic Fibrosis Foundation Consensus C. Allergic bronchopulmonary aspergillosis in cystic fibrosis-state of the art: Cystic Fibrosis Foundation Consensus Conference. Clin. Infect. Dis. 2003, v. 37, р. 225-264.
  22. Aimanianda V., Bayry J., Bozza S. et al. Surface hydrophobin prevents immune recognition of airborne fungal spores. Nature. 2009, v. 460, р. 1117-1121.
  23. Park S.J., Mehrad B. Innate immunity to Aspergillus species. Clin. Microbiol. Rev. 2009, v. 22, р. 535-551.
  24. Denning D.W., Pashley C., Hartl D. et al. Fungal allergy in asthma-state of the art and research needs. Clin. Transl. Allergy. 2014, doi: 10.1186/2045-7022-4-14.
  25. Agarwal R. Allergic bronchopulmonary aspergillosis: lessons learnt from genetics. Indian J. Chest. Dis. Allied. Sci. 2011, v. 53, p. 137-140.
  26. Knutsen A.P. Genetic and respiratory tract risk factors for aspergillosis: ABPA and asthma with fungal sensitization. Med. Mycol. 2006, v. 44, р. 61-70.
  27. Knutsen A.P., Kariuki B., Consolino J.D., Warrier M.R. IL-4 alpha chain receptor (IL-4 Ralpha) polymorphisms in allergic bronchopulmonary aspergillosis. Clin. Mol. Allergy. 2006, v. 4, р. 3.
  28. Sambatakou H., Pravica V., Hutchinson I.V., Denning D.W Cytokine profiling of pulmonary aspergillosis. Int. J. Immu-nogenet. 2006, v. 33, р. 297-302.
  29. Vaid M., Kaur S., Sambatakou H. et al. Distinct alleles of mannose-binding lectin (MBL) and surfactant proteins A (SP-A) in patients with chronic cavitary pulmonary aspergillosis and allergic bronchopulmonary aspergillosis. Clin. Chem. Lab. Med. 2007, v. 45, p. 183-186.
  30. Agarwal R., Khan A., Aggarwal A.N., Gupta D. Link between CFTR mutations and ABPA: a systematic review and meta-analysis. Mycoses. 2012, v. 55, р. 357-365.
  31. Vicencio A.G., Chupp G.L., Tsirilakis K. et al. CHIT1 mutations: genetic risk factor for severe asthma with fungal sensitization? Pediatrics. 2010, v. 126, р. 982-985.
  32. Muro M., Mondejar-Lopez P., Moya-Quiles M.R. et al. HLA-DRB1 and HLADQB1 genes on susceptibility to and protection from allergic bronchopulmonary aspergillosis in patients with cystic fibrosis. Microbiol. Immunol. 2013, v. 57, p. 193-197.
  33. Moss R.B. Pathophysiology and immunology of allergic bronchopulmonary aspergillosis. Med. Mycol. 2005, v. 43, р. 203-206.
  34. Murdock B.J., Shreiner A.B., McDonald R.A. et al. Coevolution of TH1, TH2, and TH17 responses during repeated pulmonary exposure to Aspergillus fumigatus conidia. Infect. Immun. 2011, v. 79, p. 125-135.
  35. Agarwal R., Chakrabarti A. Clinical manifestations and natural history of allergic bronchopulmonary aspergillosis. New York, Springer. 2010, р. 707-724.
  36. Agarwal R., Gupta D., Aggarwal A.N. et al. Clinical significance of hyperattenuating mucoid impaction in allergic bronchopulmonary aspergillosis: an analysis of 155 patients. Chest. 2007, v. 132, р. 1183-1190.
  37. Agarwal R., Gupta D., Aggarwal A.N. et al. Allergic bronchopulmonary aspergillosis: lessons from 126 patients attending a chest clinic in north India. Chest. 2006, v. 130, р. 442-448.
  38. Agarwal R., Singh N., Gupta D. Pulmonary hypertension as a presenting manifestation of allergic bronchopulmonary aspergillosis. Indian J. Chest. Dis. Allied. Sci. 2009, v. 51, р. 37-40.
  39. Agarwal R., Khan A., Garg M. et al. Chest radiographic and computed tomographic manifestations in allergic bronchopulmonary aspergillosis. World J. Radiol. 2012, v. 4, р. 141-150.
  40. Agarwal R., Aggarwal A.N., Gupta D. et al. Case report: a rare cause of miliary nodules - allergic bronchopulmonary aspergillosis. Br. J. Radiol. 2009, v. 82, p. 151-154.
  41. Agarwal R., Reddy C., Gupta D. An unusual cause of hilar lymphadenopathy. Lung India. 2006, v. 23, р. 90-92.
  42. Madan K., Bal A., Agarwal R. Pleural effusion in a patient with allergic bronchopulmonary aspergillosis. Respir. Care. 2012, v. 57, р. 1509-1513.
  43. Agarwal R., Srinivas R., Agarwal A.N., Saxena A.K. Pulmonary masses in allergic bronchopulmonary aspergillosis: mechanistic explanations. Respir. Care. 2008, v. 53, р. 1744-1748.
  44. Madan K., Guleria R. Vanishing lung mass in a patient with asthma. Thorac. Dis. 2013, v. 5, р. 45-49.
  45. Agarwal R., Aggarwal A.N., Gupta D. High-attenuation mucus in allergic bronchopulmonary aspergillosis: another cause of diffuse high-attenuation pulmonary abnormality. Roentgenol. 2006, v. 186, р. 904.
  46. Baxter C.G., Denning D.W., Jones A.M. et al. Performance of two Aspergillus IgG EIA assays compared with the precipitin test in chronic and allergic aspergillosis. Clin. Microbiol. Infect. 2013, v. 19, р. 197-204.
  47. Guazzelli L.S., Xavier M.O., Oliveira F.D., Severo L.C. Chronic cavitary pulmonary aspergillosis and fungal balls. New York, Springer. 2009, р. 585-620.
  48. Agarwal R., Khan A., Aggarwal A.N. et al. Clinical relevance of peripheral blood eosinophil count in allergic bronchopulmonary aspergillosis. Infect. Public Health. 2011, v. 4, р. 235-243.
  49. Agarwal R., Khan A., Gupta D. et al. An alternate method of classifying allergic bronchopulmonary aspergillosis based on high-attenuation mucus. PLoS ONE. 2010, doi: 10.1371/ journal.pone.0015346.
  50. Agarwal R., Aggarwal A.N., Garg M. et al. Allergic bronchopulmonary aspergillosis with aspergilloma: an immunologically severe disease with poor outcome. Mycopathologia. 2012, v. 174, р. 193-201.
  51. Moss R.B. Critique of trials in allergic bronchopulmonary aspergillosis and fungal allergy. Med. Mycol. 2006, v. 44, р. 269-272.
  52. Agarwal R., Gupta D., Aggarwal A.N. et al. Clinical significance of decline in serum IgE Levels in allergic bronchopulmonary aspergillosis. Respir. Med. 2010, v. 104, р. 204-210.
  53. Agarwal R., Garg M., Aggarwal A.N. et al. Serologic allergic bronchopulmonary aspergillosis (ABPA-S): long-term outcomes. Respir. Med. 2012, v. 106, р. 942-947.
  54. Agarwal R. What is the current place of azoles in allergic bronchopulmonary aspergillosis and severe asthma with fungal sensitization. Expert Rev. Respir. Med. 2012, v. 6, р. 363-371.
  55. Denning D.W., Park S., Lass-Florl C. et al. High-frequency triazole resistance found in nonculturable Aspergillus fumigatus from lungs of patients with chronic fungal disease. Clin. Infect. Dis. 2011, v. 52, р. 1123-1129.
  56. Burgel P.R., Baixench M.T., Amsellem M. et al. High prevalence of azole resistant Aspergillus fumigatus in adults with cystic fibrosis exposed to itraconazole. Antimicrob. Agents Chemother. 2012, v. 56, р. 869-874.

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