Contact dermatitis as a result of the aggression of the environment. How to treat?

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Background. To estimate the efficiency, tolerability of mometasone furoate cream «Momat» in treating of allergic contact dermatitis. Methods. There were involved 42 patients suffering from allergic contact dermatitis. The patients were applying mometasone furoate cream 1 time per day during 2-3 weeks according to the submitted written instructions. Index SCOREPI (SCOre de Reparation de l’EPIderme) and 5D-scale assessment of pruritus (index shows changes in the sensation of pruritus over time) have been used as the methods of estimation of the efficiency of therapy. Results. In 98% of participants compliance with prescribed therapy was achieved. This corresponds to a global data about the impact of various factors on adherence of patients suffering from allegic contact dermatitis. Researchers evaluated the tolerability of «Momat» cream as «good» in the majority of cases and «very good» or «excellent» in 93% of patients. Conclusion. According to the study it can be concluded that application of «Momat» cream once a day during 2 weeks is effective and safe.

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Y K Kuznetsova

Sechenov First Moscow State Medical University



  1. Смирнов В.С., Саватеева-Любимова Т.Н., Саватеев А.В. Влияние комбинированного препарата глицирризиновой кислоты и глутамил-триптофана на течение контактного дерматита у крыс. Вестник дерматологии и венерологии. 2013, № 5, с. 125-131.
  2. Rand G., Petrocelli S. Fundamental of Aquatic Toxicology. New York. Hemisphere Publishing Corporation. 1985, 666 р.
  3. Nosbaum A., Vocanson M., Rozieres A., Hennino A., Nicolas J.F. Allergic and irritant contact dermatitis. Eur. J. Dermatol. 2009, v. 19, р. 325-332.
  4. Kadyk D.L., McCarter K., Achen F. et al. Quality of life in patients with allergic contact dermatitis. J. Am. Acad. Dermatol. 2003, v. 49, р. 1037-1048.
  5. Roggenkamp D., Falkner S., Stäb F. et al. Atopic keratinocytes induce increased neurite out-growth in a coculture model of porcine dorsal root ganglia neurons and human skin cells. J. Invest. Dermatol. 2012, v. 132, р. 1892-1900.
  6. Катунина О.Р., Чикин В.В., Знаменская Л.Ф., Иноятова Л.А. Роль нейромедиаторов в развитии воспаления в коже больных атопическим дерматитом. Вестник дерматологии и венерологии. 2013, № 5, с. 91-101.
  7. Steinhoff M., Stander S., Seelinger S. et al. Modem aspects of cutaneous neurogenic inflammation. Arch. Dermatol. 2003, v. 139, р. 1479-1488.
  8. Адаскевич В.П. Диагностические индексы в дерматологии. М., «Издательство Бином». 2014, с. 132-134.
  9. Slodownik D., Lee A., Nixon R. Irritant contact dermatitis: a review. Australas J. Dermatol. 2008, v. 49, р. 1-9.
  10. Weston W.L. The use and abuse of topical steroids. Contemp. Pediatr. 1988, v. 5, р. 57-66.
  11. Barton B.E., Jakway J.P., Siegel V.I. Cytokine Inhibition by a Novel Steroid, Mometasone Furoate. Immunopharmacollmmunotoxicol. 1991, v. 13, р. 251-261.
  12. Garcia Ponte L., Ebert U. Frontiers of rapid itch relief: a review of methylprednisolone aceponate. J. Eur. Acad. Dermatol. Venereol. 2012, v. 26, р. 9-13.
  13. Blume-Peytavi U., Metz M. Atopic dermatitis in children: management of pruritus. J. Eur. Acad. Dermatol. Venereol. 2012, v. 26, р. 2-8.
  14. Ahluwalia A. Topical glucocorticoids and the skin--mechanisms of action: an update. Mediators Inflamm. 1998, v. 7, р. 183-193.
  15. Ahluwalia A., Newbold P., Brain S.D., Flower R.J. Topical glucocorticoids inhibit neurogenic inflammation: involvement of lipocortin 1. Eur. J. Pharmacol. 1995, v. 283, р. 193-198.
  16. Свирщевская Е.В., Матушевская Е.В. Сравнительный анализ эффективности и безопасности фторированных и хлорированных топических глюкокортикостероидов. Современные проблемы дерматовенерологии, иммунологии и врачебной косметологии. 2010, № 3, с. 75-78.



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