The house dust mites significance in the development of atopy

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access

Abstract


Background. Knowledge of the structure and particularity of sensitization in the region allows us to choose the correct tactics of treatment and prevention of atopic reactions. Objective. To study the structure of sensitization to inhalation allergens in Moscow and Moscow region since 2009 to 2017 and to determine significance of sensitization to house dust mites Dermatophagoides pteronyssinus (Der p) and Dermatophagoides farinae (Der f) in it. Methods. Blood serum of Moscow region patients with atopy (n=2546) was examined by RIDA AllergyScreen method in the period from 2009 to 2017. Results. The allergosensitisation structure was determined. It was revealed that there was no decreasing of the frequency of house dust mites (Der р and Der f) sensitization in observation period. The features of monovalent, polyvalent and combined sensitization among patients with IgE reactions to Der р and Der f were analyzed. Conclusions. According to our research 20% of patients with atopy in Moscow region have sensitization to Der р and/or Der f. The percentage of allergosensitisation to Der р is higher than to Der f. Most often house dust mites sensitization combined with pollen sensitization.

Restricted Access

S Yu Petrova

Mechnikov Research Institute of Vaccines and Sera

Email: laball@yandex.ru

S V Khlgatian

Mechnikov Research Institute of Vaccines and Sera

V M Berzhets

Mechnikov Research Institute of Vaccines and Sera

  1. Grieger JA, Clifton VL, Tuck AR, Wooldridge AL, Robertson SA, Gatford KL. In utero Programming of Allergic Susceptibility. Int. Arch. Allergy Immunol. 2016; 169: 80-92. doi: 10.1159/000443961.
  2. Курбачёва ОМ, Козулина И.Е. И. вновь об аллергии: эпидемиология и основы патогенеза, диагностики, терапии. Российская ринология. 2014; (4): 46-50 DOI: 10.17116/ rosrino201422446-50.
  3. Ferreira MAR, Vonk JM, Baurecht H., Marenholz I., Tian C., Hoffman JD et al. Eleven loci with new reproducible genetic associations with allergic disease risk. J. Allergy Clin Immunol. 2018; 360. Available from: https://p.360pubmed.com/pubmed/29679657 doi: 10.1016/j.jaci.2018.03.012.
  4. Custovic А., Simpson А. The Role of Inhalant Allergens in Allergic Airways Disease. Journal of Investigational Allergology and Clinical Immunology. 2012; 22: 393-401.
  5. Коровкина ЕС, Мокроносова М.А. Аллергия к клещам домашней пыли с позиций молекулярной аллергологии. Медицинская иммунология. 2012; (4-5): 280-282 doi: 10.15789/1563-06252012-4-5-279-288.
  6. Литвенкова И.А. Биолого-акарологическая характеристика акарофауны жилых помещений севера Беларуси. Вестник ВГУ. 2011; (63): 45
  7. Ксенофонтова ВА, Бержец ВМ, Федоскова Т.Г. Аллер-ген-специфическая иммунотерапия аллергенами клещей домашней пыли. Иммунопатология, Аллергология, Инфектология. 2013; (3): 47-53
  8. Ахапкина ИГ, Жёлтикова Т.М. Сравнительный анализ содержания клещей домашней пыли и их аллергенов в жилых помещениях г. Москвы. Иммунология. 2013; (2): 109
  9. Жёлтикова ТМ, Антропова АБ, Мокроносова М.А. Многолетняя динамика акарокомплекса домашней пыли и структуры сенсибилизации к бытовым аллергенам у атопических больных. Иммунология. 2016; (1): 26 doi: 10.18821/0206-4952-2016-37-1-25-28.
  10. Гланц С. Медико-биологическая статистика. М.: Практика. 1999

Views

Abstract - 29

PDF (Russian) - 0

PlumX

Dimensions

Refbacks

  • There are currently no refbacks.

Copyright (c) 2018 Russian Allergological Journal

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies