Current view on studying of the role of tropomyiosin in the development of crossallergic reactions

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Abstract


Cross-reactivity to proteins is the issue of the day due to the severity of clinical symptoms, high prevalence of this phenomenon and the absence of preventive measures . Cross-reactivity is found in pollen, house dust, insects, food allergy, helminthes etc. Multiple studies have confirmed the important role of the protein tropomyosin in the development of sensitization to house dust mites allergens, food allergens and insects. The presence of tropomyosin is detected in the allergen spectrum of many arthropods, in particular insects and crustaceans. The researchers have noted the possibility of development of various cross-allergic reactions to tropomyosin protein. Arthropods are the main type of the Earth’s fauna. Clinical symptoms of allergic reactions to Arthropods differ in severity; this is the issue of studying of the the cross-reactivity to tropomyosin protein.

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T G Fedoskova

NRC Institute of Immunology FMBA of Russia

Email: tatger@mail.ru

A I Martynov

NRC Institute of Immunology FMBA of Russia

N V Kobizskaya

NRC Institute of Immunology FMBA of Russia

D V Shabanov

NRC Institute of Immunology FMBA of Russia

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