CELL AND HUMORAL IMMUNITY IN PATIENTS WITH ALZHEIMER’S DISEASE AND MILD COGNITIVE IMPAIRMENT

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Abstract

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About the authors

I K Malashenkova

National Research Center «Kurchatov Institute» FSCC of physical-chemical medicine FMBA of Russia Moscow, Russia

N A Hailov

National Research Center «Kurchatov Institute» Moscow, Russia

G V Kazanova

National Research Center «Kurchatov Institute» Moscow, Russia

S A Krynskiy

National Research Center «Kurchatov Institute» FSCC of physical-chemical medicine FMBA of Russia Moscow, Russia

D P Ogurtsov

National Research Center «Kurchatov Institute» FSCC of physical-chemical medicine FMBA of Russia Moscow, Russia

N D Selezneva

Mental Health Research Center Moscow, Russia

Y B Fedorova

Mental Health Research Center Moscow, Russia

E V Ponomareva

Mental Health Research Center Moscow, Russia

I V Kolyhalov

Mental Health Research Center Moscow, Russia

S I Gavrilova

Mental Health Research Center Moscow, Russia

I A Kompaneetz

FSCC of physical-chemical medicine FMBA of Russia Moscow, Russia

M A Zharova

FSCC of physical-chemical medicine FMBA of Russia Moscow, Russia

N A Didkovsky

FSCC of physical-chemical medicine FMBA of Russia Moscow, Russia

References

  1. Takeda S., Sato N., Morishita R. Systemic inflammation, blood-brain barrier vulnerability and cognitive/non-cognitive symptoms in Alzheimer disease: relevance to pathogenesis and therapy. Front Aging Neurosci. 2014, v. 29, p. 6-171.
  2. Gonzalez-Quintela A., Alende R., Gude F. et al. Serum levels of immunoglobulins (IgG, IgA, IgM) in a general adult population and their relationship with alcohol consumption, smoking and common metabolic abnormalities. Clin. Exp. Immunol. 2008, v. 151, p. 42-50.
  3. Marsh S.E., Abud E.M., Lakatos A. et al. The adaptive immune system restrains Alzheimer’s disease pathogenesis by modulating microglial function. Proc. Natl. Acad. Sci. USA. 2016, v. 113, p. 1316-1325.

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