FEATURES OF CLINICAL COURSE AND TREATMENT STRATEGY FOR PATIENTS SUFFERING FROM BRONCHIAL ASTHMA IN COMBINATION WITH OBESITY

Background. Obesity is considered to be one of the risk factors for the development of bronchial asthma (BA) and the reasons for lack of control can probably influence on inflammation of respiratory tract. However, the nature of these relationships needs to be clarified. The aim of the research was to characterise it clinically, functionally, allergologically and endocrinologically, to highlight the features of the course and to define the tactics of treating patients suffering from bronchial asthma in combination with obesity. Methods. The research was made on the basis of the National Research Center - Institute of Immunology of Federal Medical-Biological Agency of Russia: both in outpatient and inpatient conditions. A statistical analysis of 367 patients treated in inpatient conditions due to exacerbation of asthma of various severity and different BMI was performed. 40 patients with BA who satisfied all inclusion criteria and did not have exclusion criteria were treated in outpatient conditions. Patients were divided into two groups. The main group consisted of 20 patients suffering from asthma and having a BMI of more than 30 kg/m2. A control group consisted of 20 patients suffering from asthma and having a normal BMI. Results. When the data of the research was analyzed, it was found that the prevalence of obesity among the 367 patients with asthma and being treated in inpatient conditions in 2013-2015 was 44,9% of patients, which is comparable to the prevalence of obesity among the population in general. Conclusions. The data of the patients suffering from asthma and obesity treated both in inpatient and outpatient conditions, was analyzed and it is set that obesity does not affect the severity of the clinical course of asthma. It is shown that obesity does not affect the control of symptoms of asthma.

bronchial asthma, metabolic syndrome, obesity, body mass index, VRI-diagnostics