Russian Journal of AllergyRussian Journal of AllergyРоссийский Аллергологический Журнал1810-88302686-682XPublishing House ABV Press8710.36691/RJA87ArticlesСтатьиResearch ArticleThe modern view of the role of innate and adaptive immunity in bronchial asthmaСовременные представления о роли врожденного и приобретенного иммунитета при бронхиальной астмеGalitskayaM AГалицкаяМариола Александровна

аспирант отделения бронхиальной астмы

galitskaya.mariola@yandex.ruKurbachevaO MКурбачеваОксана Михайловна

доктор медицинских наук, профессор, зав. отделением бронхиальной астмы

NRC Institute of Immunology FMBA of RussiaФГБУ «ГНЦ Институт иммунологии» ФМБА России14122018156NO6 (2018)№6 (2018)71710032020Copyright ©; 2018, Pharmarus Print MediaCopyright ©; 2018, Фармарус Принт Медиа2018Pharmarus Print MediaФармарус Принт Медиаhttps://rusalljournal.ru/raj/article/view/87

This article provides an overview of international data about immunological aspects of the pathophysiology of bronchial asthma (BA). The relationship between innate and adaptive immunity, as well as participation of various interleukins and cells in the development of inflammation in BA are presented. The possibility of the creation of new therapeutic molecules for the treatment of BA is substantiated.

Проведен анализ современной литературы по иммунологическим аспектам патофизиологии бронхиальной астмы (БА). Описана взаимосвязь врожденного и приобретенного иммунитета при БА, участие различных интерлейкинов и клеток иммунной системы в развитии воспаления при БА. Обосновывается возможность создания новых молекул с потенциалом лечебных средств для терапии БА.

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