Russian Journal of AllergyRussian Journal of AllergyРоссийский Аллергологический Журнал1810-88302686-682XPublishing House ABV Press81410.36691/RJA814ArticlesСтатьиH1-ANTIHISTAMINES FOR THE TREATMENT OF CHILDREN WITH ALLERGIC DISEASEАНТИГИСТАМИННЫЕ ПРЕПАРАТЫ В ЛЕЧЕНИИАЛЛЕРГИЧЕСКИХ ЗАБОЛЕВАНИЙ У ДЕТЕЙPampuraA NПампураА Н

ФГУ «Московский НИИ педиатрии и детской хирургии» М инзравсоцразвития России

PampuraА N

Federal state organization «Moscow Research Institute of Pediatrics and Child Surgery»

ФГУ «Московский НИИ педиатрии и детской хирургии» М инзравсоцразвития РоссииFederal state organization «Moscow Research Institute of Pediatrics and Child Surgery»1510201185NO5 (2011)№5 (2011)545810032020Copyright ©; 1970, Pharmarus Print MediaCopyright ©; 1970, Фармарус Принт Медиа1970Pharmarus Print MediaФармарус Принт Медиаhttps://rusalljournal.ru/raj/article/view/814

The article is devoted to modern approaches of H1-antihistamines for the treatment of children with allergic disease.

Статья отражает современные подходы к использованию блокаторов Н1-гистаминовых рецепторов в лечении аллергических заболеваний у детей.

allergic diseasesantihistamineschildrentherapyаллергические заболеванияантигистаминные препаратыдетитерапияNagai H., Teramachi H., Tuchiya Т. Recent Advances in the Development of Anti-allergic Drugs. Allergology International. 2006, v. 55, p. 35-42.Benedetti M.S., Plisnier M., Kaise J. et al. Absorption, distribution, metabolism and excretion of levocetirizine, the R-enantiomer of cetirizine, in healthy volunteers. Eur. J. Clin. Pharmacol. 2001, v. 57, p. 571-582.Cranswick N., Turzikova J., Hulhoven R. Levocetirizine in one-to two-year-old children: pharmacokinetic and pharmacokinetic profile. Int. J. Clin. Pharmacol. Therap. 2005, v. 43, p. 172-177.Adam K., Oswald I. The hypnotic effects of an antihistamine: promethazine. Br. J. Clin. Pharmacol. 1986, v. 22, p. 715-717.Druce H.M., Thoden W.R., Mure P. et al. Brompheniramine, loratadine, and placebo in allergic rhinitis: a placebocontrolled comparative clinical trial. J. Clin. Pharmacol. 1998, v. 38, p. 382-389.Scadding G. Optimal management of nasal congestion caused by allergic rhinitis in children: safety and efficacy of medical treatments. Paediatr. Drugs. 2008, v. 10, p. 151-162.Walker S., Khan-Wasti S., Fletcher M. et al. Seasonal allergic rhinitis is associated with a detrimental effect on examination performance in United Kingdom teenagers: case-control study. J. Allergy. Clin. Immunol. 2007, v. 120, p. 381-387.Walsh G.M. The anti-inflammatory effects of levocetirizine are they clinically relevant or just an interesting additional effect? Allergy Asthma Clin. Immunol. 2009, v. 17, p. 14.Ciprandi G., Cirillo I., Vizzaccaro A., Tosca M.A. Levocetirizine improves nasal obstruction and modulates cytokine pattern in patients with seasonal allergic rhinitis: a pilot study. Clin. Exp. Allergy. 2004, v. 34, p. 958-964.Simons F.E.R. Prospective, long-term safety evaluation of the HI-receptor antagonist cetirizine in very young children with atopic dermatitis. ETAC Study Group. Early Treatment of the Atopic Child. J. Allergy Clin. Immunol. 1999, v. 104, p. 433-440.Simons F.E.R. Early Prevention of Asthma in Atopic Children (EPAAC) Study Group. Safety of levocetirizine treatment in young atopic children: an 18-month study. Pediatr. Allergy Immunol. 2007, v. 18, p. 535-542.Grimfeld A., Holgate S.T., Canonica G.W. et al. Prophylactic management of children at risk for recurrent upper respiratory infections: the Preventia I Study. Clin. Exp. Allergy. 2004, v. 34, p. 1665-1672.Church K., Maurer M., Simons F. E. R. First-generation H1-antihistamines-more risk than expected . Allergy. 2010, p. 459-466.Ружицкая E.A, Потапова О.Н., Виноградова Т.В. и соавт. Клиническая эффективность левоцетиризина у детей с сезонным аллергическим ринитом и его влияние на количественный состав и морфологические показатели эозинофилов периферической крови. Педиатр. фармакол. 2009, № 3, с. 53-59.Hampel F., Ratner P., Haeusler J.M.C. Safety and tolerability of levocetirizine dihydrochloride in infants and children with allergic rhinitis or chronic urticaria. Allergy Asthma Proc. 2010, v. 31, p. 290-295.Sheikh A., ten Broek V.M., Brown S.G.A., Simons F.E.R. H1-antihistamines for the treatment of anaphylaxis with and without shock. Cochrane Database Syst. Rev. 2007, v. 1, CD006160.Starke P.R., Weaver J., Chowdhury B.A. Boxed warning added to promethazine labeling for pediatric use [letter]. N. Engl. J. Med. 2005, v. 352, p. 2653.Феденко Е.С. Основы рациональной терапии атопического дерматита. Рос. Аллергол. Журн. 2005, № 6, с. 32-41.Wahlgren C.F., Hagermark O., Bergstrom R. The antipruritic effect of a sedative and non-sedative antihistamine in atopic dermatitis. Br. J. Dermatol. 1990, v. 122, p. 545-551.Heyer G.R., Hornstein O.P. Recent studies of cutaneous nociception in atopic and non-atopic subjects. J. Dermatol. 1999, v. 26 (2), p. 77-86.21. Гребенченко Е.И., Гущин И.С., Феденко Е.С. Фармакологический контроль холинергической составляющей кожного зуда у больных атопическим дерматитом. Рос. Аллергол. Журн. 2009, № 5, с. 3-10.