Russian Journal of AllergyRussian Journal of Allergy1810-88302686-682XFarmarus Print Media77610.36691/RJA776Bronchial asthma «masks» are not always easy to recognize.Case reportIsakovaI Isapolner@yandex.ruPol'nerS A-GushchinI S-IsakovaI IInstitute of Immunology-PolnerS AInstitute of Immunology-GushchinI SInstitute of Immunology-Institute of Immunology1512201186172010032020Copyright © 1970, Pharmarus Print Media1970Clinical case of Churg-Strauss syndrome was described in 36-year old female patient in the course of its
development since the disease suggested start. Churg-Strauss syndromes manifestations were characterized
by high peripheral blood eosinophilia and multiple organ lesions, here include airways, heart (exudative
pericarditis), and skin (urticaria). The prescribed therapy involved cytostatic agents and pulse therapy with
glucocorticoids slowly reducing up to maintaining dose. In the course of the therapy a stable clinical disease
remission was registered. Maximally fast diagnostics of the given syndrome provides immediate start of therapy
and holds up autoimmune process. Both contribute to significant decrease of cases with severe forms and possible
complications.HypereosinophiliaChurg-Strauss syndromebronchial asthmapneumoniaangiitisгиперэозинофилиясиндром Чёрджа-Страуссбронхиальная астмапневмонияангиит[Чучалин А.Г. Гиперэозинофилия при заболеваниях органов дыхания. Тер. архив. 2003, № 3, с. 5-15.][Овчаренко С.И., Капустина В.А., Морозова Н.В. Сложности диагностики синдрома Чёрджа-Страусс. Трудный пациент. 2009, № 4-5, с. 35-38.][Churg J., Strauss L. Allergic granulomatosis, allergic angiitis, and periarteriitis nodosa. Am. J. Pathol. 1951, v. 27, p. 277-301.][Watts R.A., Carruthers D.M. Scott D.G. Epidemiology of systemic vasculitis: changing incidence of definition? Semin. Arthr. Rheum. 1995, v. 25, p. 28-34.][Клинические рекомендации для практикующих врачей. М., «Геотар-Мед.». 2010, с. 590-597.][Guillevin L. Guittard T. Bletry O. et al. Systemic necrotizing vasculitis with asthma: causes and precipitating factors in 43 cases. Lung. 1987, v. 165, p. 165-172.][Haas C., Geneau C., Odinot J.M. et al. L'angeite allergigue avec granulomatose: syndrome de Churg-Strauss. Etude retrospective de 16 observations. Ann. Med. Interne (Paris). 1991, v. 142, p. 335-342.][Churg A.M.D. Resent advances in the diagnosis of Churg-Strauss syndrome. Mod. Pathol. 2001, v. 14, p. 1284-1293.][Гордеев А.В., Мутовина З.Ю. Розанова И.В. Клиническая картина болезни Чёрджа-Страусс. Клин. мед. 2005, № 5, с. 55-60.]