Russian Journal of AllergyRussian Journal of Allergy1810-88302686-682XFarmarus Print Media73310.36691/RJA733Research ArticleTHERAPEUTIC APPROACHES TO THE URTICARIA TREATMENTShvetsS Msmshvets@gmail.comInstitute of Immunology1504201292616410032020Copyright © 2012, Pharmarus Print Media2012Urticaria is a heterogenic disorder, requires elimination of triggers and symptomatic treatment. The basic medications are antihistaminics of the second generation.крапивницаантигистаминные препараты[EAACI/GA2LEN/EDF/WAO guideline: management of urticaria Allergy. 2009, v. 64, р. 1427-1443.][Российский национальный согласительный документ. Крапивница и ангиоотек. Рекомендации для практических врачей. М., «Фармарус Принт Медиа», 2007, 128 с.][EAACI/GA2LEN/EDF guideline: management of urticaria Allergy. 2006, v. 61, p. 321-331.][EAACI/GA2LEN/EDF/WAO guideline: definition, classification and diagnosis of urticaria. Allergy. 2009, v. 64, р. 1417-1426.][Church M.K., Mauer M., Simons F.E. et Risk of first-generation H,-antihistamines: a GA2LEN position paper. Allergy 2010, v. 65, p. 459-466.][Гущин И.С. Аллергическое воспаление и его фармакологический контроль. М., «Фармарус Принт». 1998, 252 с.][Gillman S., Gillard M., Strolin Benedetti M. The concept of receptor occupancy to predict clinical efficacy: a comparison of second generation H,-antihistamines. Allergy Asthma Proc. 2009, v. 30 (4), p. 366-376.][Jauregui I., Ferrer M., Montoro L. et al. Anyihistamines in the treatment of chronic urticaria. J. Investig. Allergol. Clin. Immunol. 2007, v. 17, Suppl. 2, p. 41-52.][Nettis E., Colanardi M.C., Barra L. et al. Levocetirizine in the treatment of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study. J. Dermatol. 2006, v. 154 (3), p. 533-538.][Potter P.C., Kapp A., Maurer M. et al. Comparison of the efficacy of levocetirizine 5 mg and desloratadine 5 mg in chronic idiopathic urticaria patients. Allergy. 2009, v. 64 (4), p. 596-604.]