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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Allergy</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Allergy</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский Аллергологический Журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1810-8830</issn><issn publication-format="electronic">2686-682X</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">718</article-id><article-id pub-id-type="doi">10.36691/RJA718</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">EFFECT OF MULTILEVEL AIR CLEANING FOR PATIENTS WITH SEASONAL ALLERGIC RHINITIS AND ASTHMA</article-title><trans-title-group xml:lang="ru"><trans-title>ЭФФЕКТ МНОГОУРОВНЕВОЙ ОЧИСТКИ ВОЗДУХА С ПРИМЕНЕНИЕМ ТЕХНОЛОГИИ HyperHEPA У БОЛЬНЫХ СЕЗОННЫМ АЛЛЕРГИЧЕСКИМ РИНИТОМ И БРОНХИАЛЬНОЙ АСТМОЙ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Averyanov</surname><given-names>A V</given-names></name><name xml:lang="ru"><surname>Аверьянов</surname><given-names>Александр Вячеславович</given-names></name></name-alternatives><email>averyanovav@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Elisyutma</surname><given-names>O G</given-names></name><name xml:lang="ru"><surname>Елисютина</surname><given-names>О Г</given-names></name></name-alternatives><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Fedenko</surname><given-names>E S</given-names></name><name xml:lang="ru"><surname>Феденко</surname><given-names>Е С</given-names></name></name-alternatives><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sokurenko</surname><given-names>S I</given-names></name><name xml:lang="ru"><surname>Сокуренко</surname><given-names>С И</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Borisova</surname><given-names>T V</given-names></name><name xml:lang="ru"><surname>Борисова</surname><given-names>Т В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ilina</surname><given-names>N I</given-names></name><name xml:lang="ru"><surname>Ильина</surname><given-names>Н И</given-names></name></name-alternatives><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Federal Research Clinical Center FMBA of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий» ФМБА России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Institute of Immunology</institution></aff><aff><institution xml:lang="ru">ФГБУ «ГНЦ Институт иммунологии» ФМБА России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2012-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2012</year></pub-date><volume>9</volume><issue>5</issue><issue-title xml:lang="en">NO5 (2012)</issue-title><issue-title xml:lang="ru">№5 (2012)</issue-title><fpage>60</fpage><lpage>68</lpage><history><date date-type="received" iso-8601-date="2020-03-10"><day>10</day><month>03</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, Pharmarus Print Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, Фармарус Принт Медиа</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">Pharmarus Print Media</copyright-holder><copyright-holder xml:lang="ru">Фармарус Принт Медиа</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2014-12-15"/></permissions><self-uri xlink:href="https://rusalljournal.ru/raj/article/view/718">https://rusalljournal.ru/raj/article/view/718</self-uri><abstract xml:lang="en"><p>A randomized placebo-controlled study to evaluate the effectiveness of the air cleaning technology with device IQAir HealthPro Series Model 250 (Switzerland) for comprehensive treatment of patients with seasonal allergic rhinitis and bronchial asthma was carried out. The significant reduction in the number of pollen grains in the air space and the clinical improvement was demonstrated, but no effect on lung function, blood and nasal mucus eosinophilia was revealed.</p></abstract><trans-abstract xml:lang="ru"><p>Проведено рандомизированное, плацебо-контролируемое исследование по оценке эффективности применения технологии очистки воздуха при помощи системы IQAir серии HealthPro модель 250 (Швейцария) при включении в комплексную схему лечения больных сезонным аллергическим ринитом и бронхиальной астмой. Доказано значительное уменьшение числа пыльцевых зерен в воздухе помещения, угнетение клинических симптомов заболевания, но отсутствие эффекта на показатели функции дыхания, эозинофилию крови и назальной слизи.</p></trans-abstract><kwd-group xml:lang="en"><kwd>seasonal allergic rhinitis</kwd><kwd>asthma</kwd><kwd>air cleaner</kwd><kwd>hypoallergenic environment</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>сезонный аллергический ринит</kwd><kwd>бронхиальная астма</kwd><kwd>очиститель воздуха</kwd><kwd>гипоаллергенная среда</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Klepeis N.E., Nelson W.C., Ott W.R. et al. The National Human Activity Pattern Survey (NHAPS): a resource for assessing exposure to environmental pollutants. J. Expo Anal. Environ Epidemiol. 2001, v. 11 (3), p. 231-252.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Diette G.B., McCormack M.C., Hansel N.N. et al. 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