The purpose of the research: to study the clinic-economical efficiency of the program of observation the patients with a bronchial asthma (POPB) in the district polyclinic of the Central City Hospital №6 in Yekaterinburg. Materials and methods. The research was carried out in 2004-2005. The direct cost for the bronchial asthma (BA) treatment during a year before and a year after the POPB introduction was analyzed. The group under study (n=70; women - 41, men - 29, mean age - 52,6 year.) was formed by random selection of 164 asthmatics who were registered in 2005. Results. The costs on dispensary drug therapy (43%) and hospital treatment (31%) have prevailed among the direct costs before the POPB introduction. The treatment of severe BA needed the maximum costs (1, 070 $ for one asthmatic in a year), the treatment of mild intermittent bronchial asthma needed minimal costs (37 $ for one asthmatic in a year). The costs of dispensary drug therapy increased to 72% and the costs of hospital treatment decreased 7% after a year of the POPB introduction. The decrease of the costs of mild intermittent bronchial asthma treatment (2.3 times) was observed comparing the severe ВА (1,2 times). Conclusions. The direct costs of the BA treatment were 462$ for one asthmatic in a year. The POPB introduction brought to the reduction of direct costs 1,4 times (334$ for one asthmatics in a year) at the expense of the decrease the costs of hospitalization (6,5 times) and calls the emergency service (5.7 times). The denominated decrease of costs for mild intermittent bronchial asthma, by comparison the severe BA, was noted.