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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Allergy</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Allergy</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский Аллергологический Журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1810-8830</issn><issn publication-format="electronic">2686-682X</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">681</article-id><article-id pub-id-type="doi">10.36691/RJA681</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Allergy to latex - current state of problem</article-title><trans-title-group xml:lang="ru"><trans-title>Аллергия к латексу - современное состояние проблемы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Evdokimova</surname><given-names>T A</given-names></name><name xml:lang="ru"><surname>Евдокимова</surname><given-names>Татьяна Алексеевна</given-names></name></name-alternatives><email>et2005@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Fedorova</surname><given-names>O S</given-names></name><name xml:lang="ru"><surname>Федорова</surname><given-names>О С</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Fedotova</surname><given-names>M M</given-names></name><name xml:lang="ru"><surname>Федотова</surname><given-names>М М</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Siberian State Medical University</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО СибГМУ Минздравсоцразвития России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2012-02-15" publication-format="electronic"><day>15</day><month>02</month><year>2012</year></pub-date><volume>9</volume><issue>1</issue><issue-title xml:lang="en">NO1 (2012)</issue-title><issue-title xml:lang="ru">№1 (2012)</issue-title><fpage>5</fpage><lpage>11</lpage><history><date date-type="received" iso-8601-date="2020-03-10"><day>10</day><month>03</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, Pharmarus Print Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, Фармарус Принт Медиа</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">Pharmarus Print Media</copyright-holder><copyright-holder xml:lang="ru">Фармарус Принт Медиа</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2014-12-15"/></permissions><self-uri xlink:href="https://rusalljournal.ru/raj/article/view/681">https://rusalljournal.ru/raj/article/view/681</self-uri><abstract xml:lang="en"><p>During the last 20 years the incidence of sensitization to latex proteins is growing. Allergy to latex is found predominantly in persons, professionally contacting with latex products: medical workers, workers employed in the manufacture of rubber products and food workers. This review describes the main clinical symptoms of latex allergy, characteristics of structural proteins and their basic biological functions. Modern methods of diagnostics and approaches to the application of specific immunotherapy for allergy to latex are presented.</p></abstract><trans-abstract xml:lang="ru"><p>В течение последних 20 лет во всем мире отмечается рост сенсибилизации к протеинам латекса. Аллергия к латексу встречается преимущественно у лиц, профессионально контактирующих с изделиями из латекса: медицинских работников, рабочих, занятых на производстве резинотехнических изделий, и работников пищевой промышленности. В настоящем обзоре описаны основные клинические проявления латексной аллергии, дана характеристика структурных протеинов и их основных биологических функций. Представлены современные методы диагностики и подходы к применению аллерген-специфической иммунотерапии аллергии к латексу.</p></trans-abstract><kwd-group xml:lang="en"><kwd>allergy to latex</kwd><kwd>sensitization</kwd><kwd>structural proteins of latex</kwd><kwd>syndrome of cross reactivity</kwd><kwd>allergen-specific immunotherapy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>аллергия к латексу</kwd><kwd>сенсибилизация</kwd><kwd>структурные протеины латекса</kwd><kwd>синдром перекрестной реактивности</kwd><kwd>аллерген-специфическая иммунотерапия</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Васильева О.С., Казакова Г.А., Батын С.З. Латексная аллергия. Пульмонология. 2002, № 2, с. 93-100.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Hepner D.L., Castells M.C. Latex Allergy: An Update. Anesth. 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