Russian Journal of AllergyRussian Journal of AllergyРоссийский Аллергологический Журнал1810-88302686-682XPublishing House ABV Press62510.36691/RJA625ArticlesСтатьиResearch ArticleTARGET THERAPY OF BRONCHIAL ASTHMA WITH LEUKOTRIENE RECEPTOR AGONISTSЦЕЛЕВАЯ ТЕРАПИЯ БРОНХИАЛЬНОЙ АСТМЫ С ПОМОЩЬЮ АНТАГОНИСТОВ ЛЕЙКОТРИЕНОВЫХ РЕЦЕПТОРОВNenashevaN MНенашеваН М1444031@gmail.comRussian medical Academy for Postgraduate EducationГБОУ ДПО Российская медицинская академия последипломного образования15102013105NO5 (2013)№5 (2013)465410032020Copyright ©; 2013, Pharmarus Print MediaCopyright ©; 2013, Фармарус Принт Медиа2013Pharmarus Print MediaФармарус Принт Медиаhttps://rusalljournal.ru/raj/article/view/625

This article describes the features of asthma phenotypes such as asthma in smokers and asthma and obesity. The role of cysteinyl leukotrienes is discussed in the formation of inflammation in these phenotypes of asthma. The leukotriene receptor antagonists, including montelukast are effective in therapy of this category of patients.

В настоящей статье рассмотрены особенности фенотипов бронхиальной астмы в сочетании с ожирением и астмы курящих пациентов. Обсуждается участие цистеиниловых лейкотриенов в формировании воспаления при этих вариантах астмы и эффективность антагонистов лейкотриеновых рецепторов, в частности монтелукаста, у курящих пациентов, страдающих астмой, и больных астмой с ожирением.

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