Russian Journal of AllergyRussian Journal of AllergyРоссийский Аллергологический Журнал1810-88302686-682XPublishing House ABV Press59010.36691/RJA590ArticlesСтатьиReview ArticleMODERN VIEW ON THE PROBLEM OF HOUSE DUST MITES SENSITIZATIONСОВРЕМЕННЫЙ ВЗГЛЯД НА ПРОБЛЕМУ СЕНСИБИЛИЗАЦИИ К АЛЛЕРГЕНАМ КЛЕЩЕЙ ДОМАШНЕЙ ПЫЛИKurbachevaO MКурбачеваО МKurbacheva@gmail.comPavlovaK SПавловаК СMelnikovaE AМельниковаЕ АInstitute of ImmunologyФГБУ «ГНЦ Институт иммунологии» ФМБА РоссииA.I. Evdokimov Moscow State Medical and Stomatological UniversityМГМСУ им. А.И. Евдокимова15102013105NO5 (2013)№5 (2013)31210032020Copyright ©; 2013, Pharmarus Print MediaCopyright ©; 2013, Фармарус Принт Медиа2013Pharmarus Print MediaФармарус Принт Медиаhttps://rusalljournal.ru/raj/article/view/590

Dermatophagoides pteronissinus, Dermatophagoides farinea and their products of vital activity are the main allergenic components of house dust. The only pathogenetic and effective method of treatment of patients with house dust mites induced allergic rhinitis and atopic bronchial asthma according to positions of evidencebased medicine is allergenspecific immunotherapy (ASIT) with house dust mites (Dermatophagoides pteronissinus, Dermatophagoides farinea) allergens. Modern data on prevalence of a sensitization to house dust mites at patients with respiratory manifestations of allergy are presented in the review, questions of carrying out ASIT by various methods with application of the standardized allergens, its efficiency and safety are discussed.

Dermatophagoides pteronissinus и Dermatophagoides farina и продукты их жизнедеятельности являются основными аллергенными компонентами домашней пыли. на сегодняшний день единственным патогенетически значимым и эффективным методом терапии больных аллергическим ринитом и атопической бронхиальной астмой с бытовой сенсибилизацией с позиций доказательной медицины является аллерген-специфическая иммунотерапия (АСИТ) аллергенами клещей домашней пыли (Der p 1, Der p 2, Der f 1, Der f 2).

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