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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Allergy</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Allergy</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский Аллергологический Журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1810-8830</issn><issn publication-format="electronic">2686-682X</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">587</article-id><article-id pub-id-type="doi">10.36691/RJA587</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">IMMUNOGENETICS AND BIOMEDICINE</article-title><trans-title-group xml:lang="ru"><trans-title>ИММУНОГЕНЕТИКА И БИОМЕДИЦИНА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Khaitov</surname><given-names>R M</given-names></name><name xml:lang="ru"><surname>Хаитов</surname><given-names>Р М</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Alexeev</surname><given-names>L P</given-names></name><name xml:lang="ru"><surname>Алексеев</surname><given-names>Л П</given-names></name></name-alternatives><email>l.p.alexeev@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Institute of Immunology</institution></aff><aff><institution xml:lang="ru">ФГБУ «ГНЦ Институт иммунологии» ФМБА России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-02-15" publication-format="electronic"><day>15</day><month>02</month><year>2013</year></pub-date><volume>10</volume><issue>1</issue><issue-title xml:lang="en">NO1 (2013)</issue-title><issue-title xml:lang="ru">№1 (2013)</issue-title><fpage>5</fpage><lpage>14</lpage><history><date date-type="received" iso-8601-date="2020-03-10"><day>10</day><month>03</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, Pharmarus Print Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, Фармарус Принт Медиа</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">Pharmarus Print Media</copyright-holder><copyright-holder xml:lang="ru">Фармарус Принт Медиа</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2015-12-15"/></permissions><self-uri xlink:href="https://rusalljournal.ru/raj/article/view/587">https://rusalljournal.ru/raj/article/view/587</self-uri><abstract xml:lang="en"><p>Review is devoted to recent achievements in human immunogenetics, physiology of HLA, genetic basis of predisposition to diseases and susceptibility to adverse environment factors implication of immunogenetics in practical medicine.</p></abstract><trans-abstract xml:lang="ru"><p>Обзор современных представлений об иммуногенетике человека, физиологической роли системы HLA, генетических основах предрасположенности к заболеваниям и чувствительности к неблагоприятным факторам внешнего воздействия, применении достижений иммуногенетики в медицинской практике.</p></trans-abstract><kwd-group xml:lang="en"><kwd>HLA</kwd><kwd>immunity</kwd><kwd>immunogenetics</kwd><kwd>HLA</kwd><kwd>polymorphism</kwd><kwd>biomedicine</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>иммунитет</kwd><kwd>иммуногенетика</kwd><kwd>полиморфизм</kwd><kwd>биомедицина</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Алексеев Л.П. 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