Russian Journal of AllergyRussian Journal of AllergyРоссийский Аллергологический Журнал1810-88302686-682XPublishing House ABV Press52710.36691/RJA527ArticlesСтатьиResearch ArticleRUPATADINE FUMARATE: NEW FORMULA - NEW THERAPEUTIC EFFICACYРупатадина фумарат: новая формула - новый терапевтический эффектMokronosovaM AМокроносоваМ Аmmokronosova@mail.ruMechnikov's Research Institute for vaccines and sera, Department of Clinical AllergologyФГБУ НИИ вакцин и сывороток им И.И. Мечникова15122014116NO6 (2014)№6 (2014)586210032020Copyright ©; 2014, Pharmarus Print MediaCopyright ©; 2014, Фармарус Принт Медиа2014Pharmarus Print MediaФармарус Принт Медиаhttps://rusalljournal.ru/raj/article/view/527

Rupatadine is a newly synthesized formula combining molecules selectively inhibiting peripheral H 1 receptors and the receptors for the platelet-activating factor. This unique combination allows suppressing the early and late phases of allergic reactions. High efficacy, non-sedating properties, possibility of high doses treatment, absence of side effects of rupatadine has been investigated for treatment of allergic rhinitis and chronic idiopathic urticaria in adults and adolescents in several controlled studies, showing a rapid onset of action and a good safety profile even in prolonged treatment periods.

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