Russian Journal of AllergyRussian Journal of AllergyРоссийский Аллергологический Журнал1810-88302686-682XPublishing House ABV Press49910.36691/RJA499ArticlesСтатьиReview ArticleBRONCHOLITIC THERAPY IN BRONCHIAL ASTHMA: PROPER CHOICEБРОНХОЛИТИЧЕСКАЯ ТЕРАПИЯ ПРИ БРОНХИАЛЬНОЙ АСТМЕ. КАК ПРАВИЛЬНО СДЕЛАТЬ ВЫБОР?KurbachevaO MКурбачеваОксана Михайловнаkurbacheva@gmail.comPolnerS AПольнерС АSmirnovD SСмирновД СInstitute of ImmunologyФГБУ «ГНЦ Институт иммунологии» ФМБА России15102014115NO5 (2014)№5 (2014)283510032020Copyright ©; 2014, Pharmarus Print MediaCopyright ©; 2014, Фармарус Принт Медиа2014Pharmarus Print MediaФармарус Принт Медиаhttps://rusalljournal.ru/raj/article/view/499

In this article the problems of improving the control of bronchial asthma through optimization of bronchodilator therapy are discussed. Cholinergic mechanisms in the pathogenesis of asthma and the possibilities of use of long-acting m-anticholinergic - tiotropium (via liquid inhaler R espimat) - in the treatment of this disease are shown. Pharmacological properties of bronchodilators are discussed to identify the main groups of patients who need tiotropium therapy.

В статье рассматривается проблема улучшения контроля над бронхиальной астмой с помощью оптимизации бронхолитической терапии. В частности, рассмотрены холинергические механизмы в патогенезе астмы и возможности применения длительно действующего м-холинолитика - тиотропия бромида (с помощью жидкостного ингалятора Респимат) - в лечении данного заболевания. Рассмотрены фармакологические свойства бронхолитических препаратов, определены основные группы пациентов, которым показана терапия тиотропиумом.

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