Russian Journal of AllergyRussian Journal of AllergyРоссийский Аллергологический Журнал1810-88302686-682XPublishing House ABV Press48210.36691/RJA482ArticlesСтатьиReview ArticleEosinophils and allergyЭозинофилы и аллергияChernyakB AЧернякБ Аba.chernyak@gmail.comVorzhevaI IВоржеваИ ИIrkutsk State Medical Academy of Postgraduate EducationГБОУ ДПО иркутская государственная медицинская академия последипломного образования15082013104NO4 (2013)№4 (2013)31210032020Copyright ©; 2013, Pharmarus Print MediaCopyright ©; 2013, Фармарус Принт Медиа2013Pharmarus Print MediaФармарус Принт Медиаhttps://rusalljournal.ru/raj/article/view/482

The results of the modern scientific researches regarding a new view on a role of eosinophils in allergy as multifunctional cells are colligated in the review. First of all, it concerns participation of eosinophils in regulation of Th2type of the immune response, in formation of allergic inflammation and tissue damage. Their role in outcome of these processes - reparation or chronization of illness, including mechanisms of tissue remodeling is also very important.

В обзоре обобщены результаты современных научных исследований, позволяющих по-новому взглянуть на роль эозинофилов при аллергии в качестве полифункциональных клеток. Прежде всего это касается участия эозинофилов в регуляции Тh2-типа иммунного ответа, в формировании аллергического воспаления и тканевом повреждении. Не менее значима их роль в исходах этих процессов - репарации или хронизации болезни, включая механизмы тканевого ремоделирования.

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