Russian Journal of AllergyRussian Journal of AllergyРоссийский Аллергологический Журнал1810-88302686-682XPublishing House ABV Press42810.36691/RJA428ArticlesСтатьиResearch ArticleCurrent strategies of allergen-specific immunotherapyСовременные стратегии АСИТ больных поллинозом с гиперчувствительностью к пыльце луговых травPavlovaK SПавловаК Сksenimedical@gmail.comKurbachevaO MКурбачеваО МInstitute of immunologyФГБУ «ГНЦ «Институт иммунологии» ФМВА России15082015124NO4 (2015)№4 (2015)162610032020Copyright ©; 2015, Pharmarus Print MediaCopyright ©; 2015, Фармарус Принт Медиа2015Pharmarus Print MediaФармарус Принт Медиаhttps://rusalljournal.ru/raj/article/view/428

The article discusses the principles of the optimal allergovaccine choice for allergen-specific immunotherapy (ASIT) for grass-pollen-allergy patients; reviewed efficacy and safety studies of the standardized mixt five-grass-pollen extract. Relatively grass sensitization is preferred use mixt grass-pollen extract is thus more suitable for specific immunotherapy, as it contains a broader repertoire of the epitopes, which approximate to the natural exposure conditions.

В статье обсуждаются принципы выбора оптимальной аллерговакцины для проведения аллерген-специфической иммунотерапии у больных поллинозом с гиперчувствительностью к луговым травам, представлен обзор исследований, посвященных изучению эффективности и безопасности стандартизованного микст-аллергенов пяти луговых трав. Относительно сенсибилизации к аллергенам пыльцы злаковых (луговых) трав предпочтительным является применение микст-аллергена с наиболее полным антигенным представительством, приближенным к естественным условиям экспозиции.

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