Russian Journal of AllergyRussian Journal of AllergyРоссийский Аллергологический Журнал1810-88302686-682XPublishing House ABV Press35610.36691/RJA356ArticlesСтатьиResearch ArticleModern view on immunopathogenesis of asthmaСовре менный взгляд на иммунопатогенез бронхиальной астмыKurbachevaO MКурбачеваО МZhestkovA VЖестковА Вavzhestkov2015@yandex.ruNagatkinD AНагаткинД АKulaginaV VКулагинаВ ВNagatkinaO VНагаткинаО ВInstitute of immunologyФГБУ «ГНЦ институт иммунологии» ФМБА РоссииSamara State Medical UniversityГБОУ высшего профессионального образования «Самарский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииGSKSamara Regional Clinical HospitalГосударственное бюджетное учреждение здравоохранения Самарская областная клиническая больница им. В.Д. Середавина15042016132NO2 (2016)№2 (2016)101410032020Copyright ©; 2016, Pharmarus Print MediaCopyright ©; 2016, Фармарус Принт Медиа2016Pharmarus Print MediaФармарус Принт Медиаhttps://rusalljournal.ru/raj/article/view/356

The modern approaches to the understanding of inflammation in the lower airways in asthma are discussed in the article. we present some recent studies that demonstrate the variety of mechanisms of the inflammatory response and the heterogeneity of patients with bronchial asthma. the immunological particularities of asthma endotypes and phenotypes are shown in this article.

В статье рассмотрены современные подходы к пониманию процессов воспаления в нижних дыхательных путях при бронхиальной астме. Приводится ряд современных исследований, которые демонстрируют многообразие механизмов воспалительной реакции и гетерогенность пациентов, страдающих бронхиальной астмой. Рассматриваются фенотипы и эндотипы бронхиальной астмы с позиции иммунологии.

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