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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Allergy</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Allergy</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский Аллергологический Журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1810-8830</issn><issn publication-format="electronic">2686-682X</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">313</article-id><article-id pub-id-type="doi">10.36691/RJA313</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Principles of selecting therapy for patients with mild asthma. RAACI and RRO agreed recommendations</article-title><trans-title-group xml:lang="ru"><trans-title>Принципы выбора терапии для больных легкой астмой Согласованные рекомендации РААКИ и РРО</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Avdeev</surname><given-names>S N</given-names></name><name xml:lang="ru"><surname>Авдеев</surname><given-names>С Н</given-names></name></name-alternatives><email>pulmo_fmba@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Aysanov</surname><given-names>Z R</given-names></name><name xml:lang="ru"><surname>Айсанов</surname><given-names>З Р</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Arkhipov</surname><given-names>V V</given-names></name><name xml:lang="ru"><surname>Архипов</surname><given-names>В В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Belevskiy</surname><given-names>A S</given-names></name><name xml:lang="ru"><surname>Белевский</surname><given-names>А С</given-names></name></name-alternatives><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Viesel</surname><given-names>A A</given-names></name><name xml:lang="ru"><surname>Визель</surname><given-names>А А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Demko</surname><given-names>I V</given-names></name><name xml:lang="ru"><surname>Демко</surname><given-names>И В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff5"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Emelyanov</surname><given-names>A V</given-names></name><name xml:lang="ru"><surname>Емельянов</surname><given-names>А В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff6"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ilina</surname><given-names>N I</given-names></name><name xml:lang="ru"><surname>Ильина</surname><given-names>Н И</given-names></name></name-alternatives><xref ref-type="aff" rid="aff7"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kurbacheva</surname><given-names>O M</given-names></name><name xml:lang="ru"><surname>Курбачёва</surname><given-names>О М</given-names></name></name-alternatives><xref ref-type="aff" rid="aff7"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Leshchenko</surname><given-names>I V</given-names></name><name xml:lang="ru"><surname>Лещенко</surname><given-names>И В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff8"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nenasheva</surname><given-names>N M</given-names></name><name xml:lang="ru"><surname>Ненашева</surname><given-names>Н М</given-names></name></name-alternatives><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ovcharenko</surname><given-names>S I</given-names></name><name xml:lang="ru"><surname>Овчаренко</surname><given-names>С И</given-names></name></name-alternatives><xref ref-type="aff" rid="aff9"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Fassahov</surname><given-names>R S</given-names></name><name xml:lang="ru"><surname>Фассахов</surname><given-names>Р С</given-names></name></name-alternatives><xref ref-type="aff" rid="aff10"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">FGBU «NRI of pulmonology» FMBA of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «НИИ пульмонологии» ФМБА России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">FGBOU DPO RMAPO Ministry of health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ДПО РМАНПО Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Russian national research medical University named after N.I. Pirogov Ministry of health of Russia</institution></aff><aff><institution xml:lang="ru">ФУВ РНИМУ им. Н.И. Пирогова Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">FGBOU VO «Kazan state medical University MOH» Ministry of health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Казанский ГМУ МЗ РФ» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff5"><aff><institution xml:lang="en">PO FGBOU VO «Krasnoyarsk state medical University Named after In. F. VoynoYasenetsky» Ministry of health of Russia</institution></aff><aff><institution xml:lang="ru">ПО ФГБОУ ВО «КрасГМУ им. проф. В.Ф. Войно-Ясенецкого» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff6"><aff><institution xml:lang="en">FGBOU VO «Northwestern state medical University Named after I.M. Mechnikov» Ministry of health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И.М. Мечникова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff7"><aff><institution xml:lang="en">Institute of Immunology</institution></aff><aff><institution xml:lang="ru">ФГБУ «ГНЦ Институт иммунологии» ФМБА России</institution></aff></aff-alternatives><aff-alternatives id="aff8"><aff><institution xml:lang="en">FGBOU VO «Ural state medical University» Ministry of health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Уральский государственный медицинский университет» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff9"><aff><institution xml:lang="en">FGAOU «First MSMU named after I.M. Sechenov» Ministry of health of Russia</institution></aff><aff><institution xml:lang="ru">ФГАОУ «Первый МГМУ им. И.М. Сеченова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff10"><aff><institution xml:lang="en">GBOU DPO «Kazan state medical Academy» - a branch of FGBOU DPO RMAPO Ministry of health of Russia</institution></aff><aff><institution xml:lang="ru">ГБОУ ДПО «Казанская государственная медицинская академия»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2017</year></pub-date><volume>14</volume><issue>3</issue><issue-title xml:lang="en">VOL 14, NO3 (2017)</issue-title><issue-title xml:lang="ru">ТОМ 14, №3 (2017)</issue-title><fpage>55</fpage><lpage>63</lpage><history><date date-type="received" iso-8601-date="2020-03-10"><day>10</day><month>03</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Pharmarus Print Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, Фармарус Принт Медиа</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Pharmarus Print Media</copyright-holder><copyright-holder xml:lang="ru">Фармарус Принт Медиа</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2019-12-15"/></permissions><self-uri xlink:href="https://rusalljournal.ru/raj/article/view/313">https://rusalljournal.ru/raj/article/view/313</self-uri><abstract xml:lang="en"><p>The recommendations represent the rating scheme of the assessment and selection of therapy for patients with mild asthma. The variety of therapeutic options for the treatment of easy asthma can provide the achievement of the disease control, or if it is impossible to create a good continuity with the next steps of therapy. Fixed IGX/ KDBA and IGX/DBA combinations increase the compliance and effectiveness of therapy. The creation of therapy algorithms of mild asthma will be an important step to optimize medical care and to attract the attention of doctors to the problem of easy asthma. The goal of recommendations. To provide clinicians with based on the results of controlled clinical trials algorithms for mild asthma treatment.</p></abstract><trans-abstract xml:lang="ru"><p>В настоящих рекомендациях представлена рейтинговая схема оценки и выбора терапии больных легкой астмой. Многообразие терапевтических опций для терапии легкой астмы позволяет чаще добиваться контроля над заболеванием, а если это невозможно, создать хорошую преемственность с последующими шагами терапии. Так, лечение фиксированными комбинациями ингаляционных глюкокортикостероидов (ИГКС) агонистов β2-адренорецепторов короткого действия (КДБА) и ИГКС/агонистов β2-адренорецепторов длительного действия (ДДБА) позволяет увеличить комплаентность, повысить эффективность терапии и создать у больного навыки для возможного перехода на прием ИГКС/формотерола в режиме единого ингалятора. Авторы полагают, что создание детальных алгоритмов терапии легкой астмы станет важным шагом для оптимизации медицинской помощи и дополнительно привлечет внимание врачей к проблеме легкой астмы. Цель рекомендаций. Предоставить врачам разных специальностей современные, взвешенные и основанные на результатах контролируемых клинических исследований рекомендации по выбору фармакотерапии больных легкой астмой. В зависимости от методологии исследования к легкой астме можно отнести от 50 до 75% от общего числа больных.</p></trans-abstract><kwd-group xml:lang="en"><kwd>asthma</kwd><kwd>pharmacotherapy</kwd><kwd>mild asthma</kwd><kwd>inhaled corticosteroids</kwd><kwd>inflammation</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>бронхиальная астма</kwd><kwd>фармакотерапия</kwd><kwd>легкая астма</kwd><kwd>ингаляционные глюкокортикостероиды</kwd><kwd>воспаление</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention, 2016. Available from: www. ginasthma.org.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Djukanovic R., Wilson J.W, Britten K.M. et al. Effect of an inhaled corticosteroid on airway inflammation and symptoms in asthma. Am. Rev. Respir. 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