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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Allergy</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Allergy</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский Аллергологический Журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1810-8830</issn><issn publication-format="electronic">2686-682X</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">184</article-id><article-id pub-id-type="doi">10.36691/RJA184</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Target immunotherapy of atopic dermatitis</article-title><trans-title-group xml:lang="ru"><trans-title>Таргетная иммунотерапия атопического дерматита</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Elisyutina</surname><given-names>O G</given-names></name><name xml:lang="ru"><surname>Елисютина</surname><given-names>Ольга Гурьевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, старший научный сотрудник, врач аллерголог-иммунолог отделения аллергологии и иммунопатологии кожи.</p></bio><email>El-olga@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">NRC Institute of Immunology FMBA ofRussia</institution></aff><aff><institution xml:lang="ru">ФГБУ «ГНЦ Институт иммунологии» ФМБА России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-02-15" publication-format="electronic"><day>15</day><month>02</month><year>2018</year></pub-date><volume>15</volume><issue>1</issue><issue-title xml:lang="en">VOL 15, NO1 (2018)</issue-title><issue-title xml:lang="ru">ТОМ 15, №1 (2018)</issue-title><fpage>7</fpage><lpage>15</lpage><history><date date-type="received" iso-8601-date="2020-03-10"><day>10</day><month>03</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2018, Pharmarus Print Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2018, Фармарус Принт Медиа</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="en">Pharmarus Print Media</copyright-holder><copyright-holder xml:lang="ru">Фармарус Принт Медиа</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2020-12-15"/></permissions><self-uri xlink:href="https://rusalljournal.ru/raj/article/view/184">https://rusalljournal.ru/raj/article/view/184</self-uri><abstract xml:lang="en"><p>The data about novel immunopathogenetic mechanisms of AD that may be a therapeutic targets for the new immune therapy are presented in the review. The current results of modern clinical trials of targeted biological agents in AD are summarized.</p></abstract><trans-abstract xml:lang="ru"><p>В обзоре представлены данные литературы, отражающие современный взгляд на иммунопатогенетические механизмы развития атопического дерматита, которые могут являться терапевтической мишенью для применения новых иммунотропных препаратов. Кратко приведены результаты основных современных клинических исследований таргетных биологических препаратов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>atopic dermatitis</kwd><kwd>immunopathogenetic mechanisms</kwd><kwd>immunotherapy</kwd><kwd>target therapy</kwd><kwd>biological therapy</kwd><kwd>monoclonal antibodies</kwd><kwd>interleukins</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>атопический дерматит</kwd><kwd>иммунопатогенетические механизмы</kwd><kwd>иммунотерапия</kwd><kwd>биологическая терапия</kwd><kwd>таргетная терапия</kwd><kwd>моноклональные антитела</kwd><kwd>интерлейкины</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Bieber T. Atopic dermatitis 2.0: from the clinical phenotype to the molecular taxonomy and stratified medicine. Allergy. 2012;67:1475-1482. 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