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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Allergy</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Allergy</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский Аллергологический Журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1810-8830</issn><issn publication-format="electronic">2686-682X</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1524</article-id><article-id pub-id-type="doi">10.36691/RJA1524</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Clinical practice guidelines</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические рекомендации</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Allergic rhinitis</article-title><trans-title-group xml:lang="ru"><trans-title>Аллергический ринит</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7691-4584</contrib-id><contrib-id contrib-id-type="spin">9941-7013</contrib-id><name-alternatives><name xml:lang="en"><surname>Astafieva</surname><given-names>Natalia G.</given-names></name><name xml:lang="ru"><surname>Астафьева</surname><given-names>Наталья Григорьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>astang@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3987-8112</contrib-id><contrib-id contrib-id-type="spin">3570-1806</contrib-id><name-alternatives><name xml:lang="en"><surname>Baranov</surname><given-names>Alexander A.</given-names></name><name xml:lang="ru"><surname>Баранов</surname><given-names>Александр Александрович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor, Academician of the Russian Academy of Sciences</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, академик РАН</p></bio><email>baranov@pediatr-russia.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7398-0562</contrib-id><contrib-id contrib-id-type="spin">1109-2810</contrib-id><name-alternatives><name xml:lang="en"><surname>Vishneva</surname><given-names>Elena A.</given-names></name><name xml:lang="ru"><surname>Вишнева</surname><given-names>Елена Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med)</p></bio><bio xml:lang="ru"><p>д.м.н.</p></bio><email>vishneva.e@yandex.ru</email><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5636-5082</contrib-id><contrib-id contrib-id-type="spin">6943-2426</contrib-id><name-alternatives><name xml:lang="en"><surname>Daihes</surname><given-names>Nikolay  A.</given-names></name><name xml:lang="ru"><surname>Дайхес</surname><given-names>Николай  Аркадьевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>admin@otolar.ru</email><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3960-830X</contrib-id><contrib-id contrib-id-type="spin">2765-9617</contrib-id><name-alternatives><name xml:lang="en"><surname>Zhestkov</surname><given-names>Alexander V.</given-names></name><name xml:lang="ru"><surname>Жестков</surname><given-names>Александр Викторович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>avzhestkov2015@yandex.ru</email><xref ref-type="aff" rid="aff5"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3556-969X</contrib-id><contrib-id contrib-id-type="spin">6715-5650</contrib-id><name-alternatives><name xml:lang="en"><surname>Ilina</surname><given-names>Natalya I.</given-names></name><name xml:lang="ru"><surname>Ильина</surname><given-names>Наталья Ивановна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>instimmun@yandex.ru</email><xref ref-type="aff" rid="aff6"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5721-1699</contrib-id><contrib-id contrib-id-type="spin">5461-1031</contrib-id><name-alternatives><name xml:lang="en"><surname>Karneeva</surname><given-names>Olga  V.</given-names></name><name xml:lang="ru"><surname>Карнеева</surname><given-names>Ольга  Витальевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Associate Professor</p></bio><bio xml:lang="ru"><p>д.м.н., доцент</p></bio><email>olya.karneeva@yandex.ru</email><xref ref-type="aff" rid="aff4"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4062-8957</contrib-id><contrib-id contrib-id-type="spin">1089-0533</contrib-id><name-alternatives><name xml:lang="en"><surname>Karpova</surname><given-names>Elena P.</given-names></name><name xml:lang="ru"><surname>Карпова</surname><given-names>Елена Петровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>edoctor@mail.ru</email><xref ref-type="aff" rid="aff7"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1078-6388</contrib-id><contrib-id contrib-id-type="spin">7493-1032</contrib-id><name-alternatives><name xml:lang="en"><surname>Kim</surname><given-names>Irina A.</given-names></name><name xml:lang="ru"><surname>Ким</surname><given-names>Ирина Анатольевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. 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(Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>lorcentr@mtu-net.ru</email><xref ref-type="aff" rid="aff8"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3250-0694</contrib-id><contrib-id contrib-id-type="spin">5698-6436</contrib-id><name-alternatives><name xml:lang="en"><surname>Kurbacheva</surname><given-names>Oksana M.</given-names></name><name xml:lang="ru"><surname>Курбачева</surname><given-names>Оксана Михайловна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>kurbacheva@gmail.com</email><xref ref-type="aff" rid="aff6"/><xref ref-type="aff" rid="aff9"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7806-9484</contrib-id><contrib-id contrib-id-type="spin">8937-1230</contrib-id><name-alternatives><name xml:lang="en"><surname>Meshkova</surname><given-names>Raisa Y.</given-names></name><name xml:lang="ru"><surname>Мешкова</surname><given-names>Раиса Яковлевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>Meshkova.raisa@yandex.ru</email><xref ref-type="aff" rid="aff10"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2209-7531</contrib-id><contrib-id contrib-id-type="spin">1312-2147</contrib-id><name-alternatives><name xml:lang="en"><surname>Namazova-Baranova</surname><given-names>Leyla S.</given-names></name><name xml:lang="ru"><surname>Намазова-Баранова</surname><given-names>Лейла Сеймуровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor, Academician of the Russian Academy of Sciences</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, академик РАН</p></bio><email>leyla.s.namazova@gmail.com</email><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3162-2510</contrib-id><contrib-id contrib-id-type="spin">3363-6170</contrib-id><name-alternatives><name xml:lang="en"><surname>Nenasheva</surname><given-names>Natalia M.</given-names></name><name xml:lang="ru"><surname>Ненашева</surname><given-names>Наталья Михайловна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>1444031@gmail.com</email><xref ref-type="aff" rid="aff7"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7571-5460</contrib-id><contrib-id contrib-id-type="spin">6289-0209</contrib-id><name-alternatives><name xml:lang="en"><surname>Novik</surname><given-names>Gennadiy A.</given-names></name><name xml:lang="ru"><surname>Новик</surname><given-names>Геннадий Айзикович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>ga_novik@mail.ru</email><xref ref-type="aff" rid="aff11"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3897-8384</contrib-id><contrib-id contrib-id-type="spin">8054-9615</contrib-id><name-alternatives><name xml:lang="en"><surname>Nosulya</surname><given-names>Evgeny V.</given-names></name><name xml:lang="ru"><surname>Носуля</surname><given-names>Евгений Владимирович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>Nosulya@bk.ru</email><xref ref-type="aff" rid="aff8"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4164-4094</contrib-id><contrib-id contrib-id-type="scopus">7004658159</contrib-id><contrib-id contrib-id-type="researcherid">P-9255-2017</contrib-id><contrib-id contrib-id-type="spin">7593-0838</contrib-id><name-alternatives><name xml:lang="en"><surname>Pavlova</surname><given-names>Ksenia S.</given-names></name><name xml:lang="ru"><surname>Павлова</surname><given-names>Ксения Сергеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.), PhD, Leading Researcher, Asthma Department</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук, ведущий научный сотрудник, отделение Бронхиальной астмы</p></bio><email>ksenimedical@gmail.com</email><xref ref-type="aff" rid="aff6"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5039-8473</contrib-id><contrib-id contrib-id-type="spin">9722-7961</contrib-id><name-alternatives><name xml:lang="en"><surname>Pampura</surname><given-names>Alexander N.</given-names></name><name xml:lang="ru"><surname>Пампура</surname><given-names>Александр Николаевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>apamputa1@mail.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7414-1293</contrib-id><contrib-id contrib-id-type="spin">9040-5720</contrib-id><name-alternatives><name xml:lang="en"><surname>Svistushkin</surname><given-names>Valery M.</given-names></name><name xml:lang="ru"><surname>Свистушкин</surname><given-names>Валерий Михайлович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>svvm3@yandex.ru</email><xref ref-type="aff" rid="aff12"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3678-7939</contrib-id><contrib-id contrib-id-type="spin">5508-1689</contrib-id><name-alternatives><name xml:lang="en"><surname>Selimzyanova</surname><given-names>Liliya R.</given-names></name><name xml:lang="ru"><surname>Селимзянова</surname><given-names>Лилия Робертовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.), Associate Professor</p></bio><bio xml:lang="ru"><p>к.м.н., доцент</p></bio><email>lilysir@mail.ru</email><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff12"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4961-9640</contrib-id><contrib-id contrib-id-type="spin">3199-9803</contrib-id><name-alternatives><name xml:lang="en"><surname>Khaitov</surname><given-names>Musa R.</given-names></name><name xml:lang="ru"><surname>Хаитов</surname><given-names>Муса Рахимович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>mr.khaitov@nrci.ru</email><xref ref-type="aff" rid="aff6"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1829-0424</contrib-id><contrib-id contrib-id-type="spin">4004-6561</contrib-id><name-alternatives><name xml:lang="en"><surname>Khaitov</surname><given-names>Rakhim M.</given-names></name><name xml:lang="ru"><surname>Хаитов</surname><given-names>Рахим Мусаевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor, Academician of the Russian Academy of Sciences</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, академик РАН</p></bio><email>rm.khaitov@nrcii.ru</email><xref ref-type="aff" rid="aff6"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Saratov State Medical University named after V.I. Razumovsky</institution></aff><aff><institution xml:lang="ru">Саратовский государственный медицинский университет имени В.И. Разумовского</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Research Institute of Pediatrics and Children’s Health of Central Clinical Hospital of the Russian Academy of Sciences</institution></aff><aff><institution xml:lang="ru">Научно-исследовательский институт педиатрии и охраны здоровья детей ЦКБ РАН</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Pirogov Russian National Research Medical University</institution></aff><aff><institution xml:lang="ru">Российский национальный исследовательский медицинский университет имени Н.И. Пирогова</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">The National Medical Research Center for Otorhinolaryngology of the Federal Medico-Biological Agency of Russia</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр оториноларингологии Федерального медико-биологического агентства</institution></aff></aff-alternatives><aff-alternatives id="aff5"><aff><institution xml:lang="en">Samara State Medical University</institution></aff><aff><institution xml:lang="ru">Самарский государственный медицинский университет</institution></aff></aff-alternatives><aff-alternatives id="aff6"><aff><institution xml:lang="en">National Research Center ― Institute of Immunology Federal Medical-Biological Agency of Russia</institution></aff><aff><institution xml:lang="ru">Государственный научный центр «Институт иммунологии» Федерального медико-биологического агентства</institution></aff></aff-alternatives><aff-alternatives id="aff7"><aff><institution xml:lang="en">Russian Medical Academy of Continuous Professional Education</institution></aff><aff><institution xml:lang="ru">Российская медицинская академия непрерывного профессионального образования</institution></aff></aff-alternatives><aff-alternatives id="aff8"><aff><institution xml:lang="en">The Sverzhevskiy Otorhinolaryngology Healthcare Research Institute</institution></aff><aff><institution xml:lang="ru">Научно-исследовательский клинический институт оториноларингологии имени Л.И. Свержевского</institution></aff></aff-alternatives><aff-alternatives id="aff9"><aff><institution xml:lang="en">Moscow State University of Medicine and Dentistry named after A.I. Evdokimov</institution></aff><aff><institution xml:lang="ru">Московский государственный медико-стоматологический университет имени А.И. Евдокимова</institution></aff></aff-alternatives><aff-alternatives id="aff10"><aff><institution xml:lang="en">Smolensk State Medical University</institution></aff><aff><institution xml:lang="ru">Смоленский государственный медицинский университет</institution></aff></aff-alternatives><aff-alternatives id="aff11"><aff><institution xml:lang="en">Saint Petersburg State Pediatric Medical University</institution></aff><aff><institution xml:lang="ru">Санкт-Петербургский государственный педиатрический медицинский университет</institution></aff></aff-alternatives><aff-alternatives id="aff12"><aff><institution xml:lang="en">First Sechenov Moscow State Medical University (Sechenov University)</institution></aff><aff><institution xml:lang="ru">Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет)</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2022-02-23" publication-format="electronic"><day>23</day><month>02</month><year>2022</year></pub-date><pub-date date-type="pub" iso-8601-date="2022-04-06" publication-format="electronic"><day>06</day><month>04</month><year>2022</year></pub-date><volume>19</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>100</fpage><lpage>141</lpage><history><date date-type="received" iso-8601-date="2022-02-16"><day>16</day><month>02</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-02-17"><day>17</day><month>02</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Pharmarus Print Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, Фармарус Принт Медиа</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Pharmarus Print Media</copyright-holder><copyright-holder xml:lang="ru">Фармарус Принт Медиа</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2024-04-06"/></permissions><self-uri xlink:href="https://rusalljournal.ru/raj/article/view/1524">https://rusalljournal.ru/raj/article/view/1524</self-uri><abstract xml:lang="en"><p>Allergic rhinitis is one of the most common diseases (~10%–24% of the population experience allergic rhinitis in the Russian Federation) occurring in the population regardless of sex and age. The urgency of the problem is associated with an increase in the number of patients and the fact that allergic rhinitis is considered a risk factor for the development of asthma.</p> <p>The clinical allergic rhinitis guideline aimed to optimize patient care, up-to-date information about the epidemiology, and disease etiology and pathogenesis. Herein, we present the actual data about the allergic rhinitis classification and its clinical signs and modern (clinical, laboratory, and instrumental) and differential diagnostics. Studies reported allergic rhinitis treatment, rehabilitation, and prevention in the guidelines. The authors describe in detail the existing healthcare options for patients with allergic rhinitis, diagnostic features, and care in partial groups of population (children and pregnant women). The clinical guidelines are recommended for medical doctors (independently from qualification), under- and postgraduate students, universities tutors, residents, and researchers.</p></abstract><trans-abstract xml:lang="ru"><p>Аллергический ринит ― одно из наиболее распространённых заболеваний (около 10–24% населения страдают аллергическим ринитом в Российской Федерации), встречающихся в популяции независимо от пола и возраста. Актуальность проблемы связана с увеличением количества больных и тем фактом, что аллергический ринит рассматривается как фактор риска развития бронхиальной астмы.</p> <p>Представленные клинические рекомендации содержат актуальную информацию по эпидемиологии, этиологии и патогенезу заболевания; в них раскрыты особенности классификации, клинической картины и течения, современные методы клинической, лабораторной и инструментальной диагностики, а также подходы к дифференциальному диагнозу аллергического ринита. Описаны методы лечения, медицинской реабилитации и профилактики. Изложены порядок оказания медицинской помощи и особенности течения у разных групп больных (дети; беременные).</p> <p>Клинические рекомендации, целью которых является оптимизация помощи больным, предназначены для практикующих врачей всех специальностей, студентов, преподавателей медицинских вузов, ординаторов, аспирантов и научных работников.</p></trans-abstract><kwd-group xml:lang="en"><kwd>allergic rhinitis</kwd><kwd>clinical practice guidelines</kwd><kwd>epidemiology</kwd><kwd>pathogenesis</kwd><kwd>clinical presentation</kwd><kwd>diagnostics</kwd><kwd>therapy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>аллергический ринит</kwd><kwd>клинические рекомендации</kwd><kwd>эпидемиология</kwd><kwd>патогенез</kwd><kwd>клиническая картина</kwd><kwd>диагностика</kwd><kwd>терапия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Allergology and Immunology: National guidelines. 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