Russian Journal of AllergyRussian Journal of AllergyРоссийский Аллергологический Журнал1810-88302686-682XPublishing House ABV Press14910.36691/RJA149ArticlesСтатьиResearch ArticleAnaphylaxis in infantsАнафилаксия у детей раннего возрастаEsakovaN VЕсаковаНаталья Владиславовна

аучный сотрудник отдела аллергологии и клинической иммунологии.

env007@rambler.ruKonjukovaN GКонюковаНаталья Георгиевна

врач аллерголог-иммунолог отделения аллергологии и клинической иммунологии.

Academician Yu.E. Veltishchev Research Clinical Institute of Pediatrics N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian FederationОСП «Научно-исследовательский клинический институт педиатрии им. акад. Ю.Е. Вельтищева» ФГБОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России15062018153VOL 15, NO3 (2018)ТОМ 15, №3 (2018)354210032020Copyright ©; 2018, Pharmarus Print MediaCopyright ©; 2018, Фармарус Принт Медиа2018Pharmarus Print MediaФармарус Принт Медиаhttps://rusalljournal.ru/raj/article/view/149

Anaphylaxis is defined as a serious generalized allergic or hypersensitivity reaction that is rapid in onset and might cause death. Number of patients with anaphylaxis is increased over the last years in all age groups. However, data of anaphylaxis in infants is limited. The knowledge of anaphylaxis in this group of patients is based only on the description of clinical case-report, a retrospective analysis of registers for severe allergic reactions of emergency treatment units. However, children of the first years of life are extremely vulnerable and they have clinical features of the development of anaphylaxis. This article summarizes information on various aspects of anaphylaxis in infants.

Анафилаксия представляет собой остро развивающуюся аллергическую реакцию, которая возникает внезапно и может явиться причиной смерти. За последние годы отмечается отчетливая тенденция увеличения количества больных во всех возрастных группах, страдающих анафилаксией. Однако работ, посвященных пациентам первых лет жизни, очень мало, поэтому знания об анафилаксии в этой группе пациентов базируются лишь на описании отдельных клинических случаев, ретроспективном анализе данных регистров по тяжелым аллергическим реакциям отделений неотложной терапии. В свою очередь именно дети первых лет жизни крайне уязвимы и имеют ряд характерных особенностей развития анафилаксии. В настоящей статье предпринята попытка обобщения имеющихся сведений по различным аспектам анафилаксии у детей раннего возраста.

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