Russian Journal of AllergyRussian Journal of Allergy1810-88302686-682XFarmarus Print Media1237Research ArticleRemission of atopic bronchial asthma in adults: a characteristic of functional and laboratory parametersZhorinaY Vjuliamart24@mail.ruAbramovskikhO Sjuliamart24@mail.ruIgnatovaG Ljuliamart24@mail.ruFederal State Budgetary Educational Institution of Higher Education «South-Urals State Medical University» of the Ministry of Healthcare of the Russian Federation15122019161S525502042020Copyright © 2019, Pharmarus Print Media2019<p>.</p>[Romagnani P., Annunziato F., Piccinni M.P. et al. Th1/ Th2 cells, their associated molecules and role in pathophysiology. Eur Cytokine Netw. 2000; 11(3): 510-511.][Global Initiative for asthma - NHLBI/WHO Workshop Report/National Heart Lung Blood Institute Updated 2016. https://ginasthma.org/ (дата обращения : 19.09.2018).][Guerra S. Clinical remission of asthma: what lies beyond? Thorax. 2005; 60(1): 5-6. DOI: 10.1136/ thx.2004.033480][Cazzoletti L., Corsico A., Albicini F. The Course of Asthma in Young Adults: A Population-Based Nine-Year Follow-Up on Asthma Remission and Control. PLoS One. 2014; 9(1): e86956. DOI: 10.1371/journal. pone.0086956.][Taylor D.R., Bateman E.D., Boulet L.P. et al. A new perspective on concepts of asthma severity and control. Eur Respir J. 2008; 32(3): 545-54. DOI: 10.1183/09031936.00155307.][Bateman E.D., Bousquet J., Busse W.W. et al. Stability of asthma control with regular treatment: an analysis of the Gaining Optimal Asthma controL (GOAL) study. Allergy. 2008; 63(7): 932-938. DOI: 10.1111/j.1398-9995.2008.01724.x.][Upham J.W., James A.L. Remission of asthma: The next therapeutic frontier? Pharmacol Ther. 2011; 130(1): 3845. DOI: 10.1016/j.pharmthera.2011.01.002.][Koh Y.Y., Sun Y.H., Lim H.S., Kim C.K., Hong S.J. Effect of inhaled budesonide on bronchial hyperresponsiveness in adolescents with clinical remission of asthma. Chest. 2001; 120(4):1140-1146. DOI: 10.1378/ chest.120.4.1140][Tiomisto L.E., Ilmarinen P., Kankaanranta H. Prognosis of new-onset asthma diagnosed in adult age. Respir Med. 2015; 109(8): 944-954. DOI: 10.1016/j. rmed.2015.05.001.][Javed A., Yoo K.H., Agarwal K. et al. Characteristics of children with asthma who achieved remission of asthma. J Asthma. 2013; 50(5): 472-479. DOI: 10.3109/02770903.2013.787625.][Covar R.A., Strunk R., Zeiger R.S. et al. Predictors of remitting, periodic, and persistent childhood asthma. J Allergy Clin Immunol. 2010; 125: 359-366.e3. DOI: 10.1016/j.jaci.2009.10.037.][Sears M.R. Predicting asthma outcomes. J Allergy Clin Immunol. 2015; 136(4): 829-836. DOI: 10.1016/ j.jaci.2015.04.048.][Чучалин А.Г., Айсанов З.Р., Чикина С.Ю., Черняк А.В., Калманова Е.Н. Федеральные клинические рекомендации Российского респираторного общества по использованию метода спирометрии. Пульмонология. 2014; 6: 11-23. [Chuchalin A.G., Aysanov Z.R., Chikina S.YU., Chernyak A.V., Kalmanova E.N. Federal guidelines of Russian Respiratory Society on spirometry. Russian Pulmonology. 2014; 6: 11-23. (In Russ.)] DOI: 10.18093/0869-0189-2014-0-6-11-24][Koh Y.Y., Kang H., Nah K.M. et al. Absence of association of peripheral blood eosinophilia or increased eosinophil cationic protein with bronchial hyperresponsiveness during asthma remission. Ann Allergy Asthma Immunol. 2003; 91(3): 297-302. DOI: 10.1016/S1081-1206(10)63533-8][Waserman S., Nair P., Snider D. et al. Local and systemic immunological parameters associated with remission of asthma symptoms in children. Allergy Asthma Clin Immunol. 2012; 8(1): 16. DOI: 10.1186/1710-1492-8-16][Kerstjens H.A., Brand P.L., de Jong P.M., Koeter G.H., Postma D.S. Influence of treatment on peak expiratory flow and its relation to airway hyperresponsiveness and symptoms. Thorax. 1994; 49(11): 1109-1115. DOI: 10.1136/thx.49.11.1109][Toorn L.M., Overbeek S.E., Prins J.B. et al. Asthma remission : does it exist? Curr Opin Pulm Med. 2003; 9 (1): 15-20. DOI: 10.1097/00063198-200301000-00003]