Russian Journal of AllergyRussian Journal of Allergy1810-88302686-682XFarmarus Print Media1218Research ArticleProblems caused unwanted immunogenicity of therapeutic proteinsAvdeevaZh Iavd-cytok@yandex.ruSoldatovA Aavd-cytok@yandex.ruBondarevV Pavd-cytok@yandex.ruMedunitsynN Vavd-cytok@yandex.ruFederal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian Federation15122019161S111202042020Copyright © 2019, Pharmarus Print Media2019<p>.</p>[Hermeling S., Crommelin D. Structure-immunogenicity relationships of therapeutic proteins. Pharm. Res. 2004; 21(6): 897-903]