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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Allergy</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Allergy</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский Аллергологический Журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1810-8830</issn><issn publication-format="electronic">2686-682X</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1201</article-id><article-id pub-id-type="doi">10.36691/RJA1201</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Current approaches to diagnostics and treatment of angioedema in pediatric patients</article-title><trans-title-group xml:lang="ru"><trans-title>Современные подходы к диагностике и лечению ангиоотеков в педиатрии</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Denisova</surname><given-names>A R</given-names></name><name xml:lang="ru"><surname>Денисова</surname><given-names>Анита Робертовна</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, ассистент кафедры детских болезней, зам. главного внештатного специалиста детского пульмонолога ДЗ г. Москвы, главный внештатный специалист детский аллерголог-иммунолог ЦАО г. Москвы</p></bio><email>D@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pampura</surname><given-names>A N</given-names></name><name xml:lang="ru"><surname>Пампура</surname><given-names>Александр Николаевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, главный внештатный специалист детский аллерголог-иммунолог ДЗ г. Москвы</p></bio><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">The State Education Institution of Higher Professional Training The First Sechenov Moscow State Medical University under Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">Федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский Университет)</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Research and Clinical Institute for Pediatrics named after Academician Yuri Veltischev of the Pirogov Russian National Research Medical University of the Russian Ministry of Health</institution></aff><aff><institution xml:lang="ru">ОСП «Научно-исследовательский клинический институт педиатрии им. академика Ю.Е. Вельтищева» ФГБОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2019-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2019</year></pub-date><volume>16</volume><issue>2</issue><issue-title xml:lang="en">VOL 16, NO2 (2019)</issue-title><issue-title xml:lang="ru">ТОМ 16, №2 (2019)</issue-title><fpage>75</fpage><lpage>81</lpage><history><date date-type="received" iso-8601-date="2020-04-02"><day>02</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2019, Pharmarus Print Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2019, Фармарус Принт Медиа</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="en">Pharmarus Print Media</copyright-holder><copyright-holder xml:lang="ru">Фармарус Принт Медиа</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2021-04-15"/></permissions><self-uri xlink:href="https://rusalljournal.ru/raj/article/view/1201">https://rusalljournal.ru/raj/article/view/1201</self-uri><abstract xml:lang="en"><p>Angioedema often occurs in childhood. The effectiveness of the management of children with angioedema is determined by understanding the pathogenesis of the disease and the selection of personalized therapy. This article provides information on the classification, clinical manifestations, diagnostics and therapy of both bradykinin and histaminergic angioedema.</p></abstract><trans-abstract xml:lang="ru"><p>Ангиоотеки довольно часто встречаются в детском возрасте. Эффективность ведения детей с ангиоотеками определяется пониманием патогенеза заболевания и подбором персонифицированной терапии. В статье представлены сведения о классификации, клинических проявлениях, диагностике и терапии как брадикинин-, так и гистаминергических ангиоотеков.</p></trans-abstract><kwd-group xml:lang="en"><kwd>angioedema</kwd><kwd>hereditary angioedema</kwd><kwd>children</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ангиоотек</kwd><kwd>наследственный ангиоотек</kwd><kwd>дети</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Zuraw BL. Urticaria and angioedema. In: Leung DYM, Szefler SJ, Bonilla FA, Akdis CA, Sampson HA, ed. Pediatric allergy: principles and practice. Oxford: Elsevier. 2016.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Madsen F, Attermann J, Linneberg A. Epidemiology of nonhe-reditary angioedema. Acta Derm Venereol. 2012;92:475-479. 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